Dysplasio epiphysialis is congenital disorder of ossification and development of epiphysis that lead to deformation of epiphyses. This disorder of is not so frequent (1). Etiology is unknown. It appears in both sexes in the same percent, sporadically, but in the several members of one family also (2). It appears in two forms, polyarticular and oligoarticular. Clinical feature characterize low growing (150-160 cm) with short clumsy fingers, incrassate joints and limited mobility. Especially characteristic of this disorder is discrepancy between low degree of subjective complaints and marked radiological changes. (1). Laboratory findings most often are not specific. Metabolism of calcium and phosphorus is not changed (2). Radiological is characteristic irregular aspect of joint flanges and articulating surfaces and narrowing of the joint spaces, cartilage sclerosis, cystic changes in joints and, not so often periarticular chondromatosis. Vertebral joints if geared manifest platispondilia and ragged of vertebral joints surfaces (2). Conclusion: Dysplasio epiphysialis multiplex is characterized with specific clinical and radiological feature and appearance in jung ages; it is often substitute with primary generalized osteoarthrosis or rheumatoid arthritis (our case). From those reasons it is very important to recognize the specific nature of this disease for the therapeutic and prognostic purpose.

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