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THE IMPORTANCE OF MEASUREMENT OF MYELOPEROXIDASE ACTIVITY IN ACUTE CORONARY SYNDROME
Institute of Biochemistry, Medical faculty, Pristina , Kosovska Mitrovica , Kosovo*
Institute of Biochemistry, Medical faculty, Pristina , Kosovska Mitrovica , Kosovo*
Institute of Biochemistry, Medical faculty, Pristina , Kosovska Mitrovica , Kosovo*
Institute of Biochemistry, Medical faculty, Pristina , Kosovska Mitrovica , Kosovo*
Published: 01.01.2011.
Volume 39, Issue 1 (2011)
pp. 23-25;
Abstract
In the last ten years significant progress has been made in understanding of role of neutrophil granulocytes and their enzyme myeloperoxidase in the evolution and complications of atherosclerosis. Myeloperoxidase plays the role in the development of vulnerable plaque associated with the development of acute coronary syndrome. There is much evidence that suggests the role of myeloperoxidase in the development of vulnerable plaque. We investigate the value of myeloperoxidase as marker of the presence of vulnerable plaques in patients with acute coronary syndrome. Myeloperoxidase activity was significantly high in serum of the patients with the diagnosis of acute coronary syndrome as reflection of the presence of vulnerable plaques. Increase in myeloperoxidase activity in serum of patients with the diagnosis of acute coronary syndrome precedes to myocardial damage.
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