The clinical and metabolic anomalies observed in patients with type 2 diabetes are associated with high risk of cardiovascular disease (particulary coronary heart disease), witch is responsible for 75% of all death in diabetic patients. Diabetic people have cardiovascular risk factors comparable to those of nondiabetics who have had myocardial infarction or stroke. To determine main risk factors for coronary heart desease (CHD) and differentes among diabetics we analyzed 86 patients.Patients in this study attended in Institute of endocrynology,diabetes and matabolic disorders in Belgrade. The diagnosis was based on typical clinical manifestation: high levels of glucose (higher than 6,1mmol/l), high cholesterol and tryglicerides, hypertension and overweight. In the control group we have had 20 adult, healty people without metabolic disorders. We found that diabetics with coronary heart disease have had the higest level of glucose (13,2mmol/l), cholesterol (6,96mmol/l),tryglicerides (2,84mmol/l). Arterial hypertension in the group of diabetic patientes with CHD have had 72,7 %, or 40 patients of 55 patients of whole group. Type 2 diabetes and hypertension share certain risk factors such as overweight, visceral obesity,and possibly insulin resistence. This study strenthgenes the hypothesis that cholesterol and the arterial hypertension have central role in develpoment of CHD, but in non-insulin depended diabetics they associated with metabolic disorders witch play an important role in increasing the risk of coronary heart disease.

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