Poremećaj podnošenja proteina kravljeg mleka se javlja kod 2-6% dece, uglavnom u dojenačkoj dobi. Cilj rada je bio da se prikažu iskustva i zapažanja u vezi sa kliničkim simptomima i znacima nepodnošenja proteina kravljeg mleka kod odojčadi. U istraživanje je bilo uključeno 121 odojče kod kojih je nepodnošenje proteina kravljeg mleka dijagnostikovano u uzrastu od petnaest dana do devet meseci. U kliničkoj prezentaciji nepodnošenja proteina kravljeg mleka dominirale su kutane smetnje, koje su utvrđene kod 88 bolesnika (72,72%), potom digestivne smetnje, zabeležene kod 68 odojčeta (56,20%), dok su respiracione tegobe bile najređe (14,87%). Ni kod jednog ispitanika nije zabeležen anafilaktički šok. Rezultati istraživanja pokazuju da u poremećaju podnošenja proteina kravljeg mleka kod odojčadi preovlađuju kutane i kutano-digestivne smetnje, dok su respiracione tegobe relativno retke.
Host A. Frequency of cow’s milk allergy in childhood. *Ann Allergy Asthma Immunol*. 2002;89(6 Suppl 1):33–7.
2.
Wood RA. The natural history of food allergy. *Pediatrics*. 2003;111(6 Pt 3):1631–7.
3.
Walker-Smith JA. Diagnostic criteria for gastrointestinal food allergy in childhood. *Clin Exp Allergy*. 1995;25 Suppl 1:20–2.
4.
Vandenplas Y, Brueton M, Dupont C, Hill D, Isolauri E, Koletzko S, et al. Guidelines for the diagnosis and management of cow’s milk protein allergy in infants. *Archives of Disease in Childhood*. 2007;92(10):902–8.
5.
Thomson M. Disorders of the esophagus and stomach in infants. *Baillers Clin Gastroenterol*. 1997;11:547–57.
6.
Shah U, Walker AW. Food allergy. In: *Pediatric Gastroenterology and Nutrition in Clinical Practice*. 2002. p. 601–13.
7.
Radlović N. Alergija na proteine kravljeg mleka. In: *Pedijatrija*. 2010. p. 275–8.
8.
Penín M, Leal M, Carrasco J, González P, Frías GE. A retrospective study of allergic diseases in children with food hypersensitivity. *Allergologia et Immunopathologia*. 2009;37(5):275–7.
Kemp AS, Hill DJ, Allen KJ, Anderson K, Davidson GP, Day AS, et al. Guidelines for the use of infant formulas to treat cows milk protein allergy: an Australian consensus panel opinion. *Medical Journal of Australia*. 2008;188(2):109–12.
11.
Johansson SGO, Bieber T, Dahl R, Friedmann PS, Lanier BQ, Lockey RF, et al. Revised nomenclature for allergy for global use. Report of the Nomenclature Review Committee of the World Allergy Organization. 2004;113(5):832–6.
12.
Host A, Halken S, Jacobsen HP, Christensen AE, Herskind AM, Plesner K. Clinical course of cow’s milk protein allergy/intolerance and atopic diseases in childhood. *Pediatric Allergy and Immunology*. 2002;13(s15):23–8.
13.
Diagnostic criteria for food allergy with predominantly intestinal symptoms. The European Society for Paediatric Gastroenterology and Nutrition Working Group for the Diagnostic Criteria for Food Allergy. *J Pediatr Gastroenterol Nutr*. 1992;14(1):108–12.
14.
Høst A, Husby S, Hansen LG, Osterballe O. Bovine beta-lactoglobulin in human milk from atopic and non-atopic mothers. Relationship to maternal intake of homogenized and unhomogenized milk. *Clinical and Experimental Allergy*. 1990;20(4):383–7.
15.
Host A. Cow’s milk protein allergy and intolerance in infancy. Some clinical, epidemiological and immunological aspects. *Pediatr Allergy Immunol*. 1994;5(5 Suppl):1–36.
16.
Hill DJ, Hosking CS. The cow milk allergy complex: Overlapping disease profiles in infancy. *Eur J Clin Nutr*. 1995;49 Suppl 1:1–12.
17.
Hill DJ, Heine RG, Cameron DJ, Francis DE, Bines JE. The natural history of intolerance to soy and extensively hydrolyzed formula in infants with multiple food protein intolerance. *J Pediatr*. 1999;135(1):118–21.
18.
Heine RG, Elsayed S, Hosking CS, Hill DJ. Cow’s milk allergy in infancy. *Curr Opin Allergy Clin Immunol*. 2002;2(3):217–25.
19.
Friedman NJ, Zeiger RS. The role of breast-feeding in the development of allergies and asthma. *Journal of Allergy and Clinical Immunology*. 2005;115(6):1238–48.
20.
Boissieu D, Matarazzo P, Rocchiccioli F, Dupont C. Multiple food allergy: A possible diagnosis in breastfed infants. *Acta Paediatr*. 1997;86(10):1042–6.
21.
Chapman JA, Bernstein IL, Lee RE, Oppenheimer J, Nicklas RA, Portnoy JM, et al. Food allergy: A practice parameter. *Ann Allergy Asthma Immunol*. 2006;96(3 Suppl 2):1–68.
22.
Bock SA. Prospective appraisal of complaints of adverse reactions to foods in children during the first 3 years of life. *Pediatrics*. 1987;79(5):683–8.
23.
Bishop JM, Hill DJ, Hosking CS. Natural history of cow milk allergy: Clinical outcome. *J Pediatr*. 1990;116(6):862–7.
24.
Alvarado MI, Alonso E, Âlvarez GM, MT IMDL. Persistencia de sensibilizacion a proteinas de leche de vaca: estudio clinico. *Allergol et Immunopathol*. 2000;28(3):189.
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