Arthrosis (A) are the degenerative-dystrophic disease of the peripheral ankles. Etiology is unknown. The genetic factor and external factors, mostly of a mechanical nature are the crucial ones, however, in the literature more emphasis is put on the infection factor and participation of immunity in the etiology of the patogenesis A. We have treated 42 patients sicked of the gonarthrosis. A majority of them is not , as expected, is in their old age, but between 40-50 old. Out of total number, 12 % has had symptoms of early sinovitis while 17% has had symptoms of reactive synovitis. Early sinovitis is characterized in lymphocytes and plasmocytes, rare neutrophils with no fibrile layers. Reactive (later) sinovitis is characterized by rare neutrophils, crystals of appatite and abundant detritus. It is most probably that an early synovitis has an immunological and later one reactive character.

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