Bone and joints tuberculosis is a secondary infection of locomotor system, caused by a Mycobacterium Tuberculo- sis. Low incidence of tuberculosis has been maintained for a long period of time due to use of efficient chemotherapy. Howe- ver, in recent years increasing number of newly registered cases is seen, due to wide use of immunosuppressive therapy, spread of HIV, aging population. Those factors influence mycobacterium more likely to become drug resistant. The objecti- ve of the study is to review epidemiological, clinical,radiology and laboratory findings of bone and joints tuberculosis in our patients, and treatment efficiency. In 15 years of prospective study, 107 different ages male and female adult patients, were treated. In most cases spinal tuberculosis was registered (24%), then hip tuberculosis (17%), knee tuberculosis (16%) and tu- berculosis of sacroiliac joint (7%). Non operative treatment with antitubercular drugs was performed in all patients, while in 41% we used operative treatment. Early diagnosis of bone and joints tuberculosis, while treated with non operative (anti tu- berculosis drugs) and operative methods are preconditions to achieve high percentages of long term remission.

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