CORRELATION OF CLINICAL AND RADIOLOGICAL FINDINGS IN HAEMODYALISED PATIENTS – SIGNIFICANCE IN RENAL OSTEODYSTROPHY TYPES DETERMINATION

R. Grbić ,
R. Grbić

Medical Faculty of Priština , Kosovska Mitrovica , Kosovo*

M. Grbić ,
M. Grbić

Secretariat of the UN TG on HIV/AIDS, Serbia Serbia

G. Šubarić-Gorgieva ,
G. Šubarić-Gorgieva

Medical Faculty of Priština , Kosovska Mitrovica , Kosovo*

D. Tabaković
D. Tabaković

Medical Faculty of Priština , Kosovska Mitrovica , Kosovo*

Published: 01.12.2010.

Volume 38, Issue 2 (2010)

pp. 51-56;

https://doi.org/10.70949/pramed201002360G

Abstract

Renal osteodystrophy is significant medical, economic and social problem. Over 90% of patients receiving chronic dialysis are facing some type of renal osteodystrophy. The objective of the study is to determine correlation between clinical and radiological findings in patients with renal osteodystrophy. Clinical study was performed in 60 adult patients, different sex and ages, receiving chronic dialysis, with developed renal osteodystrophy. All patients were having following symptoms: bone pain, muscle and joint pain. Muscle spasm were registered in 68.3% of patients, while proximal myopathy symptoms were registered in 86.6%.Dominant radiological findings were: subperiosteal resorption in 53.3% of patients, diffuse osteoporosis in 48.3%, rugger jersey in 33.3% and soft tissue calcification in 18.3%. We have registered statistically significant correlation of clinical and radiological findings. With this study we have confirmed that different types of renal osteodystrophy can be determined by comparing radiological, clinical and biochemical findings, especially in cases when bone biopsy cannot be performed.

Keywords

References

1.
S. R, MJ C. Diagnosis and Monitoring of Renal Osteodystrophy. Current Opinion in Nephrology and Hypertension. 9(6):675–81.
2.
Wittenberg A. The Rugger Jersey Spine Sign. Radiology. 230(2):491–2.
3.
Whyte MP. Extraskeletal (Ectopic) Calcification and Ossification. In: Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. p. 427–9.
4.
A. T, V. L, D. H. Bone Disease in Predialysis, Hemodialysis, and CAPD Patients: Evidence of a Better Bone Response to PTH. Kidney International. 47(5):1434–42.
5.
CM. S, G Y. Osteitis Fibrosa Cystica and Chronic Renal Failure. Journal of the American Podiatric Medical Association. 87(5):238–40.
6.
Silverman SL. The Clinical Consequences of Vertebral Compression Fracture. 13(Suppl 2):27–31.
7.
Shane E. Hypocalcemia: Pathogenesis, Differential Diagnosis, and Management. In: Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. p. 223–6.
8.
C. S, I. S, R O. Diagnosis of Renal Osteodystrophy. European Journal of Clinical Investigation. 36(Suppl 2):13–22.
9.
Rugger Jersey Spine. New York State Journal of Medicine. 80(11):1724–5.
10.
M. AG, M. C, W. S, J. B, K. K, T M. Brown Tumors of the Skull Base. Case Report and Review of the Literature Journal of Neurosurgery. 98(2):417–20.
11.
D. R, G N. Subchondral Resorption of Bone in Renal Osteodystrophy. Radiology. 118(2):315–21.
12.
Parfitt AM. Parathyroid Hormone and Periosteal Bone Expansion. Journal of Bone and Mineral Research. 17(10):1741–3.
13.
Jevtic V. Imaging of Renal Osteodystrophy. European Journal of Radiology. 46(2):85–95.
14.
AA. I, TW. O ’Neill, C. C. Mortality Associated with Vertebral Deformity in Men and Women: Results from the European Prospective Osteoporosis Study (EPOS. Osteoporosis International. 8(3):291–7.
15.
HK. G, J. L, CY. W, JA S. Vertebral Fractures in Osteoporosis: A New Method for Clinical Assessment. Journal of Clinical Densitometry. 3(3):281–90.
16.
I. F, JP. J, PL. DP, H S. Chronic Renal Failure Causing Brown Tumors and Myelopathy. Case Report and Review of Pathophysiology and Treatment Journal of Neurosurgery. 90(2 Suppl):242–6.
17.
CE. D, CJ H. Radiological Changes Associated with Certain Metabolic Bone Diseases. British Journal of Radiology. 27(323):605–18.
18.
GA. B, TE. HS, NW. L, FK P. Association of Serum Phosphorus and Calcium × Phosphate Product with Mortality Risk in Chronic Hemodialysis Patients: A National Study. American Journal of Kidney Diseases. 31(4):607–17.

Citation

Copyright

Article metrics

Google scholar: See link

The statements, opinions and data contained in the journal are solely those of the individual authors and contributors and not of the publisher and the editor(s). We stay neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Most read articles

Indexed by