Scientific researches considering the effects of glucagon on cardiovascular system show that glucagon has a certain cardiostimulative potential. The fact that glucagon accomplishes its cardiostimulative effects by activating its own, highly specific glucagonic receptors is of most importance. That's the reason why we've wanted to give more details about the effects that glucagon has on cardiovascular system in terms of having more precise image of its effects on hemodynamics and changes which can be seen on electrocardiogram. The experiment included six dogs treated with intravenous glucagon injection. Electrocardiograph and hemodynamic parameters (middle arterial pressure, central venous pressure and heart st nd rd th th th th th frequency) have been recorded in 1 , 2 , 3 , 5 , 10 , 20 , 30 and 40 minute. Electrocardiograph and heart frequency have been recorded by continuous monitoring. Middle arterial pressure has been recorded through catheter placed into a. femoralis while central venous pressure has been recorded through central venous catheter placed into v. femoralis. Having received the intravenous injection, glucagon shows extremely positive chronotropic effect, followed by ephemeral increase of middle arterial pressure, while central venous pressure has a significant decrease. Having received intravenous injection, P-R, Q-Tand T-Pinterval have been significantly shorten.

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