FLOW/ PRESSURE AND FLOW/ VOLUME CURVES IN DIFFERENTIATION OF THE OBSTRUCTIVE CHANGES IN TRACHEOBRONCHIAL TREE

N. Matinić ,
N. Matinić

Institute of Pathophysiology, Medical faculty Priština , Kosovska Mitrovica , Kosovo*

Lj. Popović ,
Lj. Popović

Institute of Pathophysiology, Medical faculty Priština , Kosovska Mitrovica , Kosovo*

M. Mirić ,
M. Mirić

Institute of Pathophysiology, Medical faculty Priština , Kosovska Mitrovica , Kosovo*

T. Đokić
T. Đokić

Institute of Pathophysiology, Medical faculty Priština , Kosovska Mitrovica , Kosovo*

Published: 01.01.2009.

Volume 37, Issue 1 (2009)

pp. 11-18;

https://doi.org/10.70949/pramed200901263M

Abstract

Conducting research in the field of respiratory function, by using measuring and testing, has many purposes. First of all, it could show us how lungs function as a whole, but also, it could lead us to the exact location of a disorder. The aim of this paper is to, by employing accurate correlation of the measured variables of the flow/volume and flow/pressure curves, determine the location of the obstruction process in the tracheobronchial tree, in central-upper airways, as well as in a segment of small airways, so called 'silent zones' of the lungs, smaller than 2 mm in internal diameter. This research included 115 healthy people and 106 patients with chronic obstructive lungs disease, of both genders. The following values of the measured lungs' function parameters were found among healthy people (% of predicted value): FVC- 93%; FEV - 91,1 %; 1 FEV x 100/ FVC- 98,7%; MEF - 107,9%; MEF - 87,5%; MEF-98,9%; Rt-147,1%; ITGV-103,3%; SRt- 130,7%. 1 25%FVC 50%FVC Among the patients with chronic obstructive bronchitis, the following results of the examined parameters were gained: FVC- 66,3%; FEV - 54,2%; FEV x 100/ FVC- 80,7%; MEF - 19,3%; MEF - 23,1%; MEF- 40,5%; Rt- 51,2%; 1 1 25%FVC 50%FVC ITGV- 162,1%; SRt- 36,2%. Finally, there was a certain number of the healthy examinees who showed that direct indicators of the air flow resistance (Rt, SRt) were not significantly changed, while indirect indicators of the respiratory tracts obstruction (MEF , MEF ) were reduced, comparing to the expected tabular results.

Keywords

References

1.
Joseph K. General Approach to the Patient With COPD. In: Clinical Management of Chronic Obstructive Pulmonary Disease. p. 89–100.
2.
Celli BR, MacNee W. Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. Eur Respir J. 23:932–46.
3.
Bates DV, Macklem PT, Cristie RV. Respiratory Function in Disease.
4.
Enright PL, Johnson LR, Connett JE, Voelker H, Buist AS. Spirometry in the Lung Health Study. 1. Methods and quality control Am Rev Respir Dis. 143:1215–23.
5.
Mead J, J.M. T, P.T. M, J.B L. Significance of the relationship between lung recoil and maximum expiratory flow. J Appl Physiol. 22:95–108.
6.
Knudson RJ, Slatin RC, Lebowitz MD, Burrows B. The maximal expiratory flow-volume curve. Normal standards, variability, and effects of age. Am Rev Respir Dis. 113:587–600.
7.
Đokić TD. Promene mehanike disanja u hroničnoj opstruktivnoj bolesti pluća s posebnim osvrtom na mehanizme kontrole bronhomotornog tonusa i ventilacije. Doktorska disertacija.
8.
McN W. Diagnosis/Differential Diagnosis/Staging of Severity, Lung Function Testing, and Radiology. In: Clinical Management of Chronic Obstructive Pulmonary Disease. p. 53–86.
9.
Sturton G, Persson C, Barnes PJ. Small airways: an important but neglected target in the treatment of obstructive airway diseases. Trends Pharmacol Sci. 29(7).
10.
Epidemiology JK. Risk Factors, and Economic Costs of COPD. In: Clinical Management of Chronic Obstructive Pulmonary Disease. p. 17–27.

Citation

Copyright

Article metrics

Google scholar: See link

The statements, opinions and data contained in the journal are solely those of the individual authors and contributors and not of the publisher and the editor(s). We stay neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Most read articles

Indexed by