Considering its importance in cell replication and differentiation, programmed cell death, DNA transcription, function of hormones, biological membranes and immunological system, zinc probably has a major role in enabling a properfunction of different tissues, organs and organic system in general. As an essential micronutrient wich is directly invo...

By Z. Stanojević, R. Mitić, S. Stević, Z. Bukumirić, B. Biševac, M. Miletić, S. Bulajić

Diabetes is the most common cause of end-stage renal disease .in United States , Europa and Japan. Approximately 40% of patients with type 1 diabetes and 5-15% of patients with type 2 diabetes eventually develop end-stage renal disease. Risk factors for development of diabetic nephropathy include hyperglycemia, hypertension, positive family history...

By T. Novaković, S. Jovanović, S. Sovtić, S. Pajović, R. Stolić

The pustula maligna is most often clinical form of antrax. Disease is today a relative Rarity, but its appearance (sporadic or in epidemia) always to be surprised, especially in the biology war. Antrax have a big significant and today, we analyzed clinical findings of pustula maligna and its differential diagnosis. ...

By M. Relić, C. Vujičić, L. Dejanović, N. Krstić, J. Ivanović

Klebsilla pneumoniae is the very rarely cause of osteomyelitis in adults, most commonly in the immunocompromised patients with extra-sceletal infections. Successful therapy of chronic refractory osteomyelitis included different orthopaedic methods of treatment, the long time antibiotics therapy and more and more freaquently treatment with adjuvant ...

By D. Mikić, G. Komljenović, S. Rudnjanin, S. Munitlak

Every anesthesiologist can meet during his/her work with the patients who are suffering from rare diseases and had to be treated with surgical procedures. In a large clinical centers availability of the equipment, mentors and continual professional education are factors that are making performances of anesthesiologist's much easier. Regional hospit...

By M. Cvetković, V. Cvetković, M. Nikolić, E. Vitić

One the of most importante charactersistics of drug is a drug safety. However, there is no absolute safety. Medicines are troughly tested in controlled clinical trials with limiting population and short duration. Experience has shown that much of our knowledge about a medicine becomes available during the subsequent prescribing practice. Therefore ...

By S. Janićijević-Hudomal, J. Rašić, R. Mitić, Z. Stanojević

The birthrate in Serbia has been falling and we are the last country in Europe according the number of newborn children. The aim of this study was to establish the birthrate trend during the period of five years on the territory of Central Kosovo and Metohija, according the data of Gynecology- Obstetrics Clinic/Gracanica, to indicate the importance...

By R. Perenić, R. Stolić, S. Kapetanović, D. Stolić

Hypokaliaemia can be cause for beginning cardiac arrhythmias in patients with acute myocardial infarction. The aim of this investigation is to determine correlation between kalium level in serum and cardiac arrhythmias and conveying, to note down in first 24 hours in patients with acute myocardial infarction (AMI). Patients in this study attended i...

By N. Vujačić

Dendritic cells (DCs) are antigen presenting cells which trace origin from bone marrow cells. These cells are discovered and described by Steinman i Cohn (1973) in peripheral lymphoid organs of mice. The cellular membrane of DCs are place of expression of plenty immunoregulatory molecules such as MHC class I and II, co stimulatory, and adhesion mol...

By Z. Anðelković, S. Leštarević, N.B. Mitić, I. Bubanović, D. Marjanović

Reactive products of oxygen are among the most potent and omnipresent threats faced by the living organism. Intracellular accumulation of reactive oxygen species such as superoxide anion, hydrogen peroxide, hydroxyl radical, and peroxy radical, can arise from toxic insults or normal metabolic processes. These species may perturb the cell's natural ...

By B. Kisić Božović, D. Mirić, M. Dragojević, I. Dragojević