EFFECTOFGLUCAGON ON HEMODYNAMIC VARIABLES, CATECHOLAMINE LEVELAND ELECTROLYTE LEVELIN THE CANINE SERA

Z. Milanović ,
Z. Milanović

Institute of Physiology, Faculty of Medicine, Medical faculty Pristina , Коsоvsка Мitrovica , Kosovo*

A. Pavlović ,
A. Pavlović

Clinic of surgery, Faculty of Medicine, Medical faculty Pristina , Коsоvsка Мitrovica , Kosovo*

P. Jovanović ,
P. Jovanović

Clinic of surgery, Faculty of Medicine, Medical faculty Pristina , Коsоvsка Мitrovica , Kosovo*

D. Radović ,
D. Radović

Institute of Physiology, Faculty of Medicine, Medical faculty Pristina , Коsоvsка Мitrovica , Kosovo*

S. Smiljić
S. Smiljić

Institute of Physiology, Faculty of Medicine, Medical faculty Pristina , Коsоvsка Мitrovica , Kosovo*

Published: 01.01.2006.

Volume 34, Issue 1 (2006)

pp. 7-13;

https://doi.org/10.70949/pramed200601123M

Abstract

Glucagon is polypeptide hormone derived from pancreas which in addition to its metabolic actions has also certain cardiovascular stimulatory effects. We've explored the effects of glucagon on hemodynamic variables (mean arterial pressure, heart rate and central venous pressure) and on catecholamine level and the electrolite level in the kanine sera. It was estimated that glucagon expressed the positive chronotropic effect and significantly lowers the central venous pressure while inconsiderably inceases mean arterial blood pressure. It also leads to transient (short-lasting) hipokaliemia and nonsignificant hipocalcemia. As the result of the action of the glucagone, the serum adrenaline concentrations were significantly increased while the serum noradrenaline concentratios were significantly decreased

Keywords

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