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REACTIVE OXYGEN SPECIES
Institute of biochemistry, Medical faculty Priština , Kosovska Mitrovica , Kosovo*
Institute of biochemistry, Medical faculty Priština , Kosovska Mitrovica , Kosovo*
Institute of biochemistry, Medical faculty Priština , Kosovska Mitrovica , Kosovo*
Institute of biochemistry, Medical faculty Priština , Kosovska Mitrovica , Kosovo*
Published: 01.01.2006.
Volume 34, Issue 1 (2006)
pp. 73-78;
Abstract
Reactive products of oxygen are among the most potent and omnipresent threats faced by the living organism. Intracellular accumulation of reactive oxygen species such as superoxide anion, hydrogen peroxide, hydroxyl radical, and peroxy radical, can arise from toxic insults or normal metabolic processes. These species may perturb the cell's natural antioxidant defence systems, resulting in damage to all of the major classes of biological macromolecules, including nuclear acids, proteins, carbohydrates and lipids. Oxidative stress has been defined as a disturbance in the prooxidant-antioxidant balance, resulting in potential cell damage. It has been implicated in several biological and pathological processes like ageing, inflammation, carcinogenesis, ischemia-reperfusion and in diseases including diabetes mellitus, atherosclerosis, and/or neurodegenerative diseases
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