Autors reports 20 ten old boy received penetrating vulns thorasic with naif at midle linea.subksifoid area. Patient with angina pectoris, hypovolemic shock end cardiac arrest received at department intensive care Clinic hospital centre Prishtine in Gracanica. In cardiogenic arrest under reanimation is introduction in general endotracheal anestesy and intervention surgery. Maden midle sternotomy and verification laesio pericardii under right cordis longth of 20 mm,hematopericard and vulnus at parietis diaphragmalis right ventricular in area septoapicalis.Past evacuation sangui from pericard heart mobilisation and made compresion phingin.Placement closure laesion with cardiorraphia prolen 0000 sec.Cooley.Lesion right pleurae mediastinalis and placement drain in right torasic cavum and drain mediastine in restrosternal area i aspiration undervother sec. Bilay. Fixation sternum with fillum metalicum sec. Kurschner. Reanimation intensive care all time and past realisation complete haemostasis along linae sutturae heart folow up substitution adecquat failure volumen total sangui plasm and cristolid. Realisation total stability hemodinamic and patient move at department intensive care. Control EKG, echocardiography and cardiac ensims 5 and 10 dely psotoperative show fingins corectly. Not signs ischemic laesaoin and disfunction conducti and arrhythmi. Haert pariets is all corectly viability and cinesy.

Endometrial carcinoma is still one of the most common malignant tumor of the female genital system in the most industrialized countries. Endometrial cancer is due to 3,9% of all female malignant tumors. The occurence of endometrial cancer varies with age. In 75% of all cases endometral carcinoma tipically occurs in postmenopausal women, with the highest incidence between 50 and 59 year. The high frequence of endometrial carcinoma in younger age is also found in women with ovarian estrogen-secreting tumors. About 10% of all endometrial carcinomas also in association with a genetic predisposition, but the most cases of endometrial carcinomas are sporadic. The most important prognostic factors for endometral carcinomas are: clinical stage, age, histopathological type and grade, as wel as hormonal receptors. Younger nulliparous women with early detected well-diferentiated endometrial carcinoma are usually treated by high doses of progesterone. Older women with endometrial carcinoma are usually treated by hysterectomy. Administration of postoperative radiation and chemiotherapy depends on clinical stage.

Helical ventricula myocardial bend of Torrent-Guasp is the revolutionary new concept in understanding global, three-dimansional, functional architecture of the ventricular myocardium. Anatomy of the VMB, and recent proofs for its segmental electrical and mechanical activation, undoubtedly indicates that ventricular filling is the consequente of an active muscular contraction. Specific septal arrangment of the ascedent segments fibers, their interaction with adjacent descedent segment fibers, elastic elements and intracavitary blood volumen explein the physical principes involvel in this action. Understanding this mechanism cudld be of particular importance in our efforts to prevent and treat diastolic heart failure.

Modulation of potassium channels is a recent modern approach to experimental and clinical investigation of potential better tocolytic medications. Assuming that potassium channels are by far the largest category of cellular ion channels, they are of crucial importance for the regulation of uterine smooth muscle tone. In the vast category of potassium channels, Maxi-K and BKCa (highly conductive, calcium-activated channels) are considered the main channels in the myometrium. It is believed that those have a key role in the modulation of uterine contractility and the homeostasis of myometrial calcium. The total number of Maxi-K channels is doubled during the onset of labor, compared to their number in pregnant and non-pregnant myometrium. We also keep getting more familiar with the characterization and control of myometrial potassium channels. Certain effects of pharmacological potassium channel modulators in isolated parts of both human and animal, both pregnant and non-pregnant myometrium will be presented in this article. Even though there have been a lot of studies on this subject, not many of them mentioned the role and modulation of potassium channels during human labor. We are still looking for the substances that will perform best in the treatment of possible miscarriages and early labor; although the use of beta sympathomimetics and calcium channel antagonists has been a major breakthrough in treatment of these pregnancy disorders. Using new tocolytic medications and a selective approach to cases of early labor, along with the use of other adequate measures, could improve the treatment of early labor in the future.

The authors in this work presented the case of itterative Caesarean Section. In this intervention they had a complication of endotracheal anaesthetic. Although general anaesthetic, according report the most authors, generally appliance anaesthetic during Caesarean Section, this anaesthetic have a certain failure. This are: difficult intubation, intubation in oesophagus, insufficient relaxation on myometrium, risk of depression - foetal’s central nervous system, unadequate reaction on drugs etc. Some authors have a pioritydaju of regional method according safety. Because of that all we believe, that heed is necessary in work and everybody obstetrician must conscious of this risk, like as application generally anaesthetic such as and regional anaesthetic by woman who has just given birth. In this effect we suggest that knowledge and experience of anaesthesiologies are very important.

Obstructive jaundice presents partial or complete blockade in the gall way towards intestinal tract. This blockade is caused by mechanical obstruction in the extrahepatitic bilioductule system. Etiologic factors which cause obstruction of the extrahepatitic gall ways are numerous. One of the reasons of appearing obstructive jaundice is penetration of the cyst parts or cyst sprout into the gall ways. Echinococcus is zoonosis, parasitic disease, caused by echinococcus granulosus, E. multilocolaris, E. vogeli i E. oligarthus. At humans, cystic form of disease caused by E. granulosus appears most frequently, while the alveolar one caused by E. multilocolaris seu alveolaris appears rarely. Aim of the work is to show the importance of the echinococcus cyst of the liver at the appearing of the obstructive jaundice , penetrating the cyst parts or cyst sprout in the gall ways. The patient presented in the work is E.C., male, register number of the disease history 404/05.06.2007, 20 years old, hospitalized at Surgical Clinic because of the surgery of echinococcus cyst on the left liver lobe. Diagnosis was set by abdomen USG, CT of the abdomen, and laboratory analyses. Echinococcus cyst got complicated by its penetration into the gall ways, and manifested by jaundice, the signs of purulent cholangiitis, and bad general state of the patient, so the surgical treatment is absolutely indicated. During the surgery, after the done pericystectomia, cholendochotomia is done because of the enlarged cholangiitis, where the signs of purulent cholangiitis and 5 cyst sprouts are found and removed. Postoperative flow passed normally. Findings of done secondary cholangiography showed normal structure and transience of gall ways, so the T-drain was removed and the patient sent to further home care in a generally and locally good state.

An anonymous poll was conducted, targeting medics in health institutions in the area of Novi Sad, Bačka Palanka, Bač, Temerin and Odžak (south Bačka region). Doctors involved in this survey are representative sample of the total population. Aim of the survey was to analyse drugs prescription and use in modern medicine, as well as to determine the extent of compliance of general medicine doctors with modern pharmacotherapy requirements. Results show that more than a half of doctors feel that the positive list corresponds to real needs, and that the price of medicaments and participation is low. Also, they believe that the drug consumption exceeds real needs. The high percent of medics does not have sufficient knowledge of the modern pharmacotherapy attitude towards the certain drugs use, which demonstrates the lack of continuing education in the field.

Breast cancer is mostfreqency malignant tumor in womans, cardinal causer of death in malignant tumots with continous ascendig of incidence and mortality. Actual therapy of breast cancer is multidisclipinary to consist in surgical, irradiant, cytostatic, hormonal and imunological therapy with specific directive based in disease stage. Surgical therapy is now more effectiveness metod of therapy and base of multidisclipinary therapy. In aim of prognosis desease conclusion and risk ratio of local relapse in currency is prognostic factors. With combination a few factors derive prognostic indexes with whose can acquire more information aggainst biologic behaviour of each neoplasm.

One of the paradoxes of life on the Earth is that, on one side, oxygen is necessary for living of aerobic organisms. On the other side, increased contrencations of oxygen and especially its reactive metabolites (reactive oxygen species) may lead to the development of number diseases such as Alzheimer, Parkinson, ischemia-reperfusion injury, coronary atherosclerosis, diabetes mellitus, hypertension, and cancer genesis, as well as in the aging process (1, 2,3). Amajor source of free radicals in biological systems is molecular oxygen (O2). By interacting with fundamental cell structures and biomolecules, reactive oxygen species (ROS) can lead to the development of many pathophysiological disorders (4,5). Active principles from plant family Lamiaceae (flavonoids and phenolic compounds, polyphenols), like plant Mellitis melisophillum, may act as new potential antioxidants.

Epileptic status is one of the most urgent conditions in medicine, whose positive outcome is directly dependent of adequate treatment. The estimation of epileptic status incidence is not available. According to population studies, the incidence varies from 16 to 18 at a sample of 100000 people. The status treatment consists of a line of procedures whose goal is to stop it in as little time as possible. Medication therapy is the basis of it, and it is needed that intravenous medications are used urgently in an adequate dose, at an adequate speed (intravenous burden dose), with an adequate symptomatic therapy and correction of eventual provocation status factors. General medications used to initially treat the status are benzodiazepines, fenitoin and fenobarbiton. Randomized studies have shown that lorazepam has pharmacokinetic advantages over diazepam and that it doesn't initiate respiratory depression as often as midazolam. Also, it is more efficient than fenitoin, and more efficient than fenobarbiton. Medication treatment is confirmed to be efficient at breaking the status at nearly all of the patients, but the final outcome depends on the initial cause. If the status cannot be ended by application of conventional doses of basic medications, then a refractory status may be discussed. It may be treated by a prolonged anesthesia using barbiturates, midazolam or lorazepam.