Although there is generally world trend in decreasing of number of smokers, expecially in developed part of world, smoking cigarettes still have large importance in morbidity and mortality of modern human population. Taking anamnestics data about smoking habit instruct anaesthesiologist to apply special strategy in general anaesthesia for a reason of possible complications provoked bby a chronic influence of nicotin and other tobbaco ingredients on different organs. In this article we wanted to examine influence of chronic tobbaco smoke exposing on arterial oxygen saturation SaO2 during and short period after general anaesthesia. Research was evaluated on patients in Emergency Center of Clinical Center of Serbia. Patients were divided in two groups (ASAI and II): group I smokers (n=40) and group II nosmokers (n=40). Our investigation has shown no statistical significant difference on SaO2 during general anaesthesia between two experimental groups. Immediately after general anaesthesia and extubation in postoperative period SaO2 dicreases (p<0.001) during transport from operating room to recovery room in both groups of patients,but the level of hypoxemia was significantly higher in smokers group. In this study we demonstrated that tobbaco smoking corellate with postoperative decrease of SaO2 after general anaesthesia, proposing an additional oxygen therapy in early postoperative period.

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