Syndroma Stevens-Johnson - toxic epidermal necrolysis overlap associated with carbamazepine in patient with secondary epilepsy caused by brain tumor (Glioblastoma multiforme)

A. Vojvodic ,
A. Vojvodic
M. Dinic ,
M. Dinic
K. Kostic
K. Kostic

Published: 01.06.2015.

Volume 44, Issue 2 (2015)

pp. 83-87;

https://doi.org/10.5937/pramed1502083v

Abstract

Stevens-Johnson syndrome (SJS) is a severe, episodic, acute mucocutaneous reaction that is most often elicited by drugs and occasionally by infections. The drugs commonly implicated as the cause of SJS are anticonvulsants, sulfonamides, non-steroidal anti-inflammatory drugs and antibiotics. Carbamazepine has been commonly implicated in SJS. We report a case of SJS-TEN overlap syndrome developing in patient who was prescribed carbamazeine after epileptic attack during radiotherapy for the purpose of treatment Glioblastoma multiforme, patients underlying disease, whose symptomatology deteriorated patients condition.

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References

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