SERUM VITAMIN D ANALYSIS IN ACUTE VIRAL BRONCHIOLITIS

Zorica Vujnović Živković ,
Zorica Vujnović Živković

Faculty of Medicine, University of Priština - Kosovska Mitrovica , Mitrovica , Kosovo

Snežana Marković Jovanović ,
Snežana Marković Jovanović

Faculty of Medicine, University of Priština - Kosovska Mitrovica , Mitrovica , Kosovo

Jovan Živković ,
Jovan Živković

Faculty of Medicine, University of Priština - Kosovska Mitrovica , Mitrovica , Kosovo

Mirjana Čukalović ,
Mirjana Čukalović

Faculty of Medicine, University of Priština - Kosovska Mitrovica , Mitrovica , Kosovo

Mirjana Čukalović ,
Mirjana Čukalović

Faculty of Medicine, University of Priština - Kosovska Mitrovica , Mitrovica , Kosovo

Tatjana Novaković ,
Tatjana Novaković

Faculty of Medicine, University of Priština - Kosovska Mitrovica , Mitrovica , Kosovo

Dragana Stamatović ,
Dragana Stamatović

Pediatric Clinic “ Primum Vivere” , Krusevac , Serbia

Jelena Krdzić ,
Jelena Krdzić

Faculty of Medicine, University of Priština - Kosovska Mitrovica , Mitrovica , Kosovo

Jadranka Mitić ,
Jadranka Mitić

Faculty of Medicine, University of Priština - Kosovska Mitrovica , Mitrovica , Kosovo

Radica Ristić ,
Radica Ristić

Faculty of Medicine, University of Priština - Kosovska Mitrovica , Mitrovica , Kosovo

Aleksandra Ilić ,
Aleksandra Ilić

Faculty of Medicine, University of Priština - Kosovska Mitrovica , Mitrovica , Kosovo

Predrag Živković
Predrag Živković

Faculty of Technical Sciences, University of Priština - Kosovska Mitrovica , Mitrovica , Kosovo

Published: 01.01.2019.

Volume 48, Issue 1 (2019)

pp. 9-14;

https://doi.org/10.70949/pramed201901417V

Abstract

Bronchiolitis is an acute viral disease of lower respitatory pathways in children under 2 years of age. It is manifested by coughing, whistling and refusing food intake. The most common cause of bronchiolitis is a respiratory syncytial virus. Vitamin D is a steroid hormone which is synthesized in the skin after sun exposure or food intake. With discovery of Vitamin D receptors and hydroxylated enzymes in immune cells, a potential role for Vitamin D in maintaining immune homeostasis was seen. It has been established that Vitamin D induces a change of the antimicrobial polypeptide, cathelicidin, which has both antibacterial and antiviral roles.

Keywords

References

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Clinical Practice Guideline: The Diagnosis, Management, and Prevention of Bronchiolitis. Pediatrics. 134.
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originally published online October 27.
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Wainwright C. Acute viral bronchiolitis in children— a very common condition with few therapeutic options. Paediatr Respir Rev. 11(39–45):45.
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Murray J, Bottle A, Sharland M, Modi N, Aylin P, Majeed A, et al. Medicines for Neonates Investigator G. Risk factors for hospital admission with RSV bronchiolitis in England: a population-based birth cohort study. PLoS One. 9.
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Thompson WW, Shay DK, Weintraub E, Brammer L, Cox N, Anderson LJ, et al. Mortality associated with influenza and respiratory syncytial virus in the United States. JAMA. 289:179–86.

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