ROLE OF ENDURANCE TRAINING (CHRONIC STRESS) ON ANTIOXIDANT SYSTEM ADAPTATION

Lj. Popović ,
Lj. Popović

Institute of pathophysiology, Medical faculty Priština , Kosovska Mitrovica , Kosovo*

R.N. Mitić ,
R.N. Mitić

Institute of pathophysiology, Medical faculty Priština , Kosovska Mitrovica , Kosovo*

I. Radić ,
I. Radić

Institute of pathophysiology, Medical faculty Priština , Kosovska Mitrovica , Kosovo*

D. Mirić ,
D. Mirić

Institute of biochemistry, Medical faculty Priština , Kosovska Mitrovica , Kosovo*

B. Krdžić
B. Krdžić

Internal clinic, Medical faculty Priština , Kosovska Mitrovica , Kosovo*

Published: 01.01.2010.

Volume 38, Issue 1 (2010)

pp. 1-6;

https://doi.org/10.70949/pramed201001317P

Abstract

It is well known that intensive physical activity increase the production of reactive species of O and N (RONS), but 2 it is also known that moderate and regular physical activity has influence on antioxidative system adaptation and help in repairing process of oxidative damage. In this paper we estimated markers of lipid peroxidation (MDA, % ind MDA), and antioxidant status (Asc, DHA/A, GSH, CAT, Pex) for 30 students (control group), and 30 professional football players (regular intensive physical activity). In the group of professional sportsman there were significant increase of lipid peroxidation markers (MDA ↑, % ind MDA ↑), which was also followed by an increased antioxidant activity (Asc ↑, DHA/A ↑, GSH ↑, Pex ↑, CAT ≈). We can conclude that chronic physical activity significantly improves antioxidant status using the adaptation process.

Keywords

References

1.
Aslan R, Sekeroglu MR, Tarakcioglu M, Bayiroglu F, Meral I. Effect of acute and regular exercise on antioxidative enzymes, tissue damage markers, and membrane lipid peroxidation of erythrocytes in sedentary students. Tr J Med Sci. 28:411–4.
2.
Svensson MB, Ekblom B, Cotgreave IA, Norman B, Sjöberg B, Ekblom Ö, et al. Adaptive stress response of glutathione and uric acid metabolism in man following controlled exercise and diet. Acta Physiol Scand. 176(1):43–51.
3.
Dalton TP, Li Q, Bittel D, Liang L, Andrews GK. Oxidative stress activates metal-responsive transcription factor-1 binding activity: Occupancy in vivo of metal response elements in the metallothionein-I gene promoter. J Biol Chem. 271(42):26233–41.
4.
Janssen YM, Sen CK. Nuclear factor kappa B activity in response to oxidants and antioxidants. Methods Enzymol. 300:363–74.
5.
Davies KJA. Oxidative stress, antioxidant defenses, and damage removal, repair, and replacement systems. IUBMB Life. 50(4–5):279–89.

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