INTRAHOSPITAL MORTALITY OF PATIENTS SUFFERING AN ACUTE MYOCARDIAL INFARCTION AND THE IMPORTANCE OF MYOCARDIAL REINFARCTION IN THE INTRAHOSPITAL PERIOD

Z. Marčetić ,
Z. Marčetić

Internal clinic, Medical faculty Pristina , Kosovska Mitrovica , Kosovo*

S. Sovtić ,
S. Sovtić

Internal clinic, Medical faculty Pristina , Kosovska Mitrovica , Kosovo*

Z. Stašević ,
Z. Stašević

CHC Pristina - Gracanica Bosnia and Herzegovina

T. Novaković ,
T. Novaković

Internal clinic, Medical faculty Pristina , Kosovska Mitrovica , Kosovo*

D. Đikić ,
D. Đikić

CHC Pristina - Gracanica Bosnia and Herzegovina

S. Vasić ,
S. Vasić

CHC Pristina - Gracanica Bosnia and Herzegovina

G. Antić ,
G. Antić

CHC Pristina - Gracanica Bosnia and Herzegovina

D. Rašić ,
D. Rašić

Internal clinic, Medical faculty Pristina , Kosovska Mitrovica , Kosovo*

S. Lazić ,
S. Lazić

Internal clinic, Medical faculty Pristina , Kosovska Mitrovica , Kosovo*

M. Šipić ,
M. Šipić

Internal clinic, Medical faculty Pristina , Kosovska Mitrovica , Kosovo*

V. Perić
V. Perić

Internal clinic, Medical faculty Pristina , Kosovska Mitrovica , Kosovo*

Published: 01.12.2008.

Volume 36, Issue 2 (2008)

pp. 17-23;

https://doi.org/10.70949/pramed200802243M

Abstract

Conclusion about efficacious of some medication can be given based on reducing morbidity and mortality in patients treated with that medication.. Aim of this work was to estimate intrahospital mortality in patients with acute myocardial infarction (AMI), role of myocardial reinfarction in that and side effects of medications in patients who were different treated in initial phase of AMI, based on what they were separated in three different therapeutic groups: group treated with thrombolytic therapy, group treated with beta-blockers and group treated with nitrates. It was shown that intrahospital mortality is highest in patients treated with nitrates but there was not significant difference between thera-peutic groups in frequency of myocardial reinfarction while frequency of complications and side effects were in range as in others similar studies.

Keywords

References

1.
M. H, P. T, H. CJ, V F. Prevention of Early and Late Rethrombosis and Further Strategies After Coronary Reperfusion. In: Thrombolysis in Cardiovasc Disease. p. 203–29.
2.
R. R, W. R, H. M. TIMI II-B Study): Immediate versus deferred beta-blockade following thrombolytic therapy in patients with acute myocardial infarction. Circulation. 83:422–37.
3.
Kažić T. Beta blokatori.
4.
ISIS-1 Collaborative Group: Randomized trial of intravenous atenolol among 16027 cases suspected acute myocardial infarction; ISIS-1. Lancet. :57–66.
5.
Z. M, G T. Radojičić S.: Kliničke karakteristike i prognoza netransmuralnog infarkta srca. Praxis Medica, Priština. 25. (br.1-2:42–6.
6.
sar VZ. Jednogodišnje praćenje bolesnika sa non-Q infarktom. Uticaj primenjene antiishemične terapije. U zborniku radova XI kongresa kardiologa Jugoslavije. 16. (Suppl. 1.
7.
P. R, H. B, K K. R.: Selective intracoronary thrombolysis in acute myocardial infarction and unstable angina pectoris. Circulation. 63:307–17.
8.
M. OE. Consequences of reocclusion after successful reperfusion therapy in acute myocardial infarction. Circulation. 82:781–91.
9.
H. SD. Reinfarction, recurrent angina, and reocclusion after thrombolytic therapy. Circulation. 76(suppl. II):57-62.
10.
J. RW. Return of left ventricular function after reperfusion in patients with myocardial infarction: importance of subtotal stenoses or intact collaterals. Circulation. 69:338–49.
11.
MIAMI: Metoprolol in acute myocardial infarction. Am J Cardiol. :56.
12.
S. SJ. Effects of dilatation of distal coronary arteries in the dog. Am J Cardiol. 43:219–24.
13.
P. SW, P W. Altered coronary flow responses to vasoactive drugs in the presence of coronary arterial stenosis in the dog. Am J Cardiol. 45(276).
14.
Santamore W. P.: Altered coronary flow responses in the presence of coronary arterial stenosis in the dog. Circulation. 63(61).
15.
R. F. Influence of Thrombolytic Therapy on Mortality and Cardiogenic Shock in Acute Myocardial Infarction. J Am Coll Cardiol. 4:663–70.
16.
J. BS, W. G, K CS. Cardiogenic Shock Following Acute Myocardial Infarction. Am J Cardiol. 58:168–75.
17.
H. GG. Meta-analysis of thrombolytic therapy for myocardial infarction. JAMA. 274:2134–9.
18.
W. BG. Efficacy of thrombolysis in acute myocardial infarction. Am J Cardiol. 66:237–42.
19.
L. NP. Effect of thrombolysis in acute myocardial infarction: a meta-analysis. Eur Heart J. 13:20–5.
20.
D. WW. Early thrombolysis with tissue plasminogen activator in acute myocardial infarction: A meta-analysis. J Am Coll Cardiol. 26:564–9.
21.
E. B, R K. A.: Myocardial reperfusion: A double-edged sword? J Clin Invest. 76(1713).
22.
H. CJ, G. K, R. R. Thrombolysis in myocardial infarction (TIMI) trial, Phase I: A comparison between intravenous plasminogen activator and intravenous streptokinase. Circulation. 76:142–54.
23.
The ISAM Study Group: A prospective trial of intravenous streptokinase in acute myocardial infarction. N Engl J Med. 314:1465–71.
24.
W. KJ, L. RJ, B. DK, L. SM, C. M, K FJ. The Western Washington myocardial infarction, A-12 month follow-up report. N Engl J Med. 312:1073–8.
25.
sar JG. Analiza intrahospitalnog mortaliteta u bolesnika sa akutnim infarktom miokarda lečenih intravenskom streptokinazom. U zborniku radova II kongresa kardiologa Srbije. 17. (Suppl. 1.
26.
sar SG. Desetogodišnje praćenje bolesnika sa akutnim infarktom miokarda lečenih intrakoronarnom streptazom. U zborniku radova XI kongresa kardiologa Jugoslavije. 16. (Suppl. 1.
27.
Marčetić Z. Vujović D.: Evolucija akutnog infarkta miokarda u bolesnicima tretiranim intravenskom streptokinazom. Anali, Priština. :62–70.
28.
J TE. Thrombolytic intervention. In: Textbook of interventional cardiology. p. 68–111.
29.
P DD. Should We Intervene Following Thrombolysis? The SWIFT trial of delayed elective intervention vs conservative treatment after thrombolysis with anistreplase in acute myocardial infarction. Eur Heart J. 10(253).
30.
F. M, M. DA, G. FM. In-hospital causes of death in patients admitted to the GISSI trial. G Ital Cardiol. 17:37–44.
31.
Gruppo Italiano per lo Studio della Streptochinasi nell Infarcto Miocardico (GISSI). Long-term effects of intravenous thrombolysis in acute myocardial infarction: final report of the GISSI study. Lancet. 2:871–4.
32.
J. SP, I. TRF, K. MJ. Sustained limitation of myocardial reperfusion injury by a monoclonal antibody that alters leukocyte function. Circulation. 81:226–37.
33.
Đorđević B. S.: Značaj pojave aritmija u akutnom infarktu miokarda i fiziopatija poremećaja ritma. In: U zborniku radova: Poremećaji srčanog ritma, Niška banja. p. 201–6.
34.
sar VV. Analiza intrahospitalnog mortaliteta u bolesnika sa akutnim infarktom miokarda lečenih i. 16. (Suppl. 1.
35.
Z. M, D V. Terapijski efekti trombolitičke terapije u bolesnika sa akutnim infarktom miokarda komplikovanim teškim srčanim popuštanjem. U zborniku radova I jugoslovenskog kongresa o farmakoterapiji kardiovaskularnih oboljenja.
36.
sar NJ. Dvogodišnja prognoza pacijenata sa akutnim infarktom miokarda u odnosu na antikoagulantnu, antiagregacionu i drugu medikamentoznu terapiju. U zborniku radova XI kongresa kardiologa Jugoslavije. 16. (Suppl. 1.
37.
sar VI. Beta blokatori u akutnom infarktu miokarda - petogodišnje iskustvo rada koronarne jedinice, KBC “dr Dragiša Mišović” - Dedinje - Beograd. U zborniku radova XI kongresa kardiologa Jugoslavije. 16. (Suppl. 1.
38.
Bošković D. Beta blokatori u akutnom infarktu miokarda. U zborniku radova XI kongresa kardiologa Jugoslavije. 16. (Suppl. 1.
39.
D. M, R. M, W L. The effects of metoprolol given early in acute myocardial infarction on ventricular arrhythmias. Eur Heart J. 7:217–23.
40.
L. R, R. A, K. A. A double-blind trial of metoprolol in acute myocardial infarction. Effects on ventricular tachyarrhythmias N Eng J Med. 308:614–8.

Citation

Copyright

Article metrics

Google scholar: See link

The statements, opinions and data contained in the journal are solely those of the individual authors and contributors and not of the publisher and the editor(s). We stay neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Most read articles

Indexed by