L-carnitine is assorted with non-vitamin nutritives (metavitamines) on the grounds of importance to the living process, while itb similar to aminoacids in terms of structure. It has multistructural role in functioning of an organism while one of the most important and best investigated roles is the sphere of energizing metabolism because it is needed for the transport of the longchain fatty acids into the mitochondria where they are subject to a β oxidation. It has widespread clinical application in prevention and therapy of: genetic and secondarycarnithine deficiency, cardiovascular disease, lipid metabolism disorder, carbohydrate metabolism disorder, aciduria of organic acids, renal and liver insuficiency, neuropathy, miopathy, as well as the means for improvent of fitness capacites of sportsmen. L-carnitine is crucial part of organism of mamals, therefore it can be applied in relatively big doses whereby it requires no detoxication in liver, on the contrary, it significaty increases its detoxication capacites. Key words: L-carnitine, Physiology, Prevention , Therapy. L-carnitine is assorted with non-vitamin nutritives (metavitamines) on the grounds of importance to the living process, while itb similar to aminoacids in terms of structure. It has multistructural role in functioning of an organism while one of the most important and best investigated rol condarycarnithine deficiency, cardiovascular disease, lipid metabolism disorder, carbohydrate metabolism disorder, aciduria of organic acids, renal and liver insuficiency, neuropathy, miopathy, as well as the means for improvent of fitness capacites of sportsmen. L-carnitine is crucial part of organism of mamals, therefore it can be applied in relatively big doses whereby it requires no detoxication in liver, on the contrary, it significaty increases its detoxication capacites.

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