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Pediatrics Clinic, Faculty of Medicine, University of Priština - Kosovska Mitrovica, Mitrovica, Kosovo
Published: 01.01.2003.
Volume 31, Issue 1 (2003)
pp. 91-92;
Abstract
Until sixties of twenty centuries, it was little now abaot cancer. It was well-know than chemicals , radiation, onko viruses, can to provoke cancer.Untill seventies it was clear than cancer is not infection or inborn sicness.Than eighties discovering onko-gens (gens normal indebted for growth of cell who is mute. Understad is than cancer cell could be continue growth, and they must have onko gen ON and cancer supresor OFF. Discover so and fenomena of apoptosissuicide cell what something wrong begin.For the time of nineties thay are discover reasons of apoptosis. The main one is TP53 gen on short part of hromosoma 17, with 1179 letter. It's understand than cancer begining with muting gens what is reason of growth, continuing with muting gens what suprim growing and finish with fold of last defence muting gen TP53.In therapy of cancer is searcing for agenc who will stimulate apoptosis.Big step what genetics do on understanding cancer give us reall chance to beat cancer.
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