Treatment, rehabilitation and aesthetics should be the main tasks of modern dentistry. Adequate prosthetic therapy and rehabilitation may be conditioned by different factors. The paper describes prosthetic rehabilitation of a patient, 55 years old woman, with abnormalities in the vertical dimension of occlusion and malocclusion of the third class, and all in order to return of aesthetics and the function of stomatognathic system. The patient came to the clinic due to disturbed aesthetics and function, where was achieved the appropriate amount of bite along with satisfactory aesthetics and functional results due to a combination of fixed and partial dentures. Two metal-ceramic bridges consisted of 13 pieces were built in the upper jaw, and 8 teeth mobile partial denture in lower jaw, thus resulting in satisfactory requirements set to re-establish aesthetics and function of stomatognathic system. 

Introduction: Most permanent teeth erupt and establish proper occlusion. In some cases, the permanent teeth have a problem in the eruption and remain impacted in bone.There are two possibilities. 1. Extraction of impacted tooth and its replacement implant or a prosthetic replacement, 2. Surgical release of the impacted teeth and orthodontic traction in the dental arch. The time of treatment, type of surgery release impacted teeth, orthodontic techniques and possible problems during treatment, depending on the type of the impacted tooth and its location. Case report: Clinical examination 14-year-old patients concluded the lack of maxillary canine teeth in the dental arch. Panoramic image showed bilateral canine impaction in the upper jaw. The analysis of X-ray image was recorded axial and in the middle alveolar position of both the impacted tooth. This is why we chose the of closed eruption method. Discussion: Impacted maxillary canines, the middle alveolar ridge treated by closed eruption, except for a slight increase in clinical crown of the tooth does not show other changes deteriorate.

Gastrointestinal stromal tumors are the most common mesenchymal tumors of the gastrointestinal tract. Anatomic locations, in decreasing, are: stomach (60%), small intestine (30%), colon and rectum (5%), oesophagus (5%). Histogenesis is still unclear, criteria of malignancies are not adapted, biological behavior in not known, and the diagnosis and prognosis are questionaly. Although usually asymptomatic, large gastrointestinal stromal tumor may present with repeated bleeding. Most often diagnosis in mode during the explorative laparotomy and postoperative immunohistochemical analysis of specimen. In this paper we have analized patients with gastrointestinal stromal tumors of the oesophagus. The patient preoperatively diagnosed submucosal tumor of the esophagus presented with repeated gastrointestinal bleeding. After the resuscitation, we performed total gastrectomy. The immunohistochemical analysis proved benign GIST. Surgical resection is a treatment of choice gastrointestinal stromal tumors presented with gastrointestinal bleeding. 

Aim: There is a few data in the literature on the medical significance of Mesobuthus gibbosus whose sting is considered potentially hazardous for human health. In this case two patients in the age of 16 and 25 with diagnosed scorpionism Mesobuthus gibbosus are described.Here is the example of woman 49 years old who had scorpionism, Euscorpius italicus. Case report: The stings by Mesobuthus gibbosus in both cases occurred during the construction work done by tourists. The following general symptomes were noticed: excitement, pulsating pains, muscle cramps in legs, pallor and profuse sweating. Local symptoms were: paresthesis, bruised skin, erythematous swelling with a red spot in the centre.After two years one patient had occasional muscle twitching, extension of superficial vein and pain on her injured leg. Sting by Euscorpius italicus happened in a bathroom while doing her physiological needs. The local symptoms were: swelling, redness and pain. The general symptoms were: numbness of a neck, intensive salivation and nausea. The symptomatic therapy was implemented in all three cases and was successful. Conclusions: Mesobuthus gibbosus and Euscorpius italicus can be found at the Montenegrian coast and represents a real danger for the health of the local community and tourists. Therapy of these scorpionism is only symptomatic.

Epstein-Barrov virus (EBV) is a cause of heterophile antibody positive infectious mononucleosis (IM),which is characterized by fever, sore throat, limfadenopatiom and atypical limfocitozom. IM is mainly a self-limited disease. Complications of the central nervous system, hepatitis (which can be fulminant), (splenomegalia, obstruction of the upper respiratory tract with bacterial can sometimes be deadly.

Because of it’s anabolic and lipolytic effects and with the beginnings of the production of recombinant growth hormone for the treatment of many congenital diseases began and growth hormone abuse in sport. His contributions to enhancing the physical performances of athletes are debatable, and there are many side effects. Detection of growth hormone use as doping agents is impossible by standard means of doping because of the identity of its recombinant and natural forms. There are various tests measuring its isoforms and collagen peptide, while the use of carbon isotope is still under investigation. Efficient detection tests, the use of "athlete passport" and education of athletes, are good way to prevent misuse of growth hormone.

In this review paper, metabolism of most used inhaled halogenated anesthetics (halothane, enflurane, isoflurane, desulfurane and sevoflurane) is shown Only part of the anesthetics is metabolized, while the remainder is eliminated unchanged. They are metabolized by mixed function oxidases (reductive or oxidative pathways). 

In the study with experimental animals in vitro conditions, the aim of the research was to examine the effect of verapamil on the even brawniness of the isolated organ of the respiratory ways (tracheas) in guinea-pigs on acetylcholine and histamine, and in that way, to examine local mechanisms of smooth muscle system but also to exclude the rest of the neurohumoral influences. The guinea-pigs of both sexes (average weight of 500-700 gr), were used for this experiment. 10 guinea-pigs were included in the experimental research; the trachea was taken from them after the immolation. The preparations of isolated organs of trachea were divided into two groups (A and B). The previous incubation of trachea -5 isolated by verapamil (1 minute) in concentration 10 M significantly reduced the contraction caused by acetylcholine -4 (ascent 21.49±9.63, r=0.97, p<0.05). Concentration of verapamil 10 M also caused significant fall of contraction (ascent -5 21.3±12.63, r=0.95, p<0.05). Verapamil in concentration 10 M significantly reduces the response of isolated trachea cau- -6 -5 -4 sed by histamine in concentrations 10 M and 10 M (slope 21.3±10.6, r=0.96, p<0.05).Concentration of verapamil 10 M significantly reduced the contraction of smooth muscles of isolated trachea caused by histamine (slope 15.46±10.47, r= 0.94, p < 0.05).

Conducting research in the field of respiratory function, by using measuring and testing, has many purposes. First of all, it could show us how lungs function as a whole, but also, it could lead us to the exact location of a disorder. The aim of this paper is to, by employing accurate correlation of the measured variables of the flow/volume and flow/pressure curves, determine the location of the obstruction process in the tracheobronchial tree, in central-upper airways, as well as in a segment of small airways, so called 'silent zones' of the lungs, smaller than 2 mm in internal diameter. This research included 115 healthy people and 106 patients with chronic obstructive lungs disease, of both genders. The following values of the measured lungs' function parameters were found among healthy people (% of predicted value): FVC- 93%; FEV - 91,1 %; 1 FEV x 100/ FVC- 98,7%; MEF - 107,9%; MEF - 87,5%; MEF-98,9%; Rt-147,1%; ITGV-103,3%; SRt- 130,7%. 1 25%FVC 50%FVC Among the patients with chronic obstructive bronchitis, the following results of the examined parameters were gained: FVC- 66,3%; FEV - 54,2%; FEV x 100/ FVC- 80,7%; MEF - 19,3%; MEF - 23,1%; MEF- 40,5%; Rt- 51,2%; 1 1 25%FVC 50%FVC ITGV- 162,1%; SRt- 36,2%. Finally, there was a certain number of the healthy examinees who showed that direct indicators of the air flow resistance (Rt, SRt) were not significantly changed, while indirect indicators of the respiratory tracts obstruction (MEF , MEF ) were reduced, comparing to the expected tabular results.

The origin of ophthalmic artery (OA) and surrounding structures was investigated in 25 cadavers by three different methods: macroscopic, stereomicroscopic, and histological observations. The following results were obtained. In 42% of the specimens the origin of the OAwas observable in the cranial cavity and defined as the intradural type, running alongside the optic nerve within the subarachnoid space. The other 58% were named the extradural type of the OA, originated within the cavernous wall or cavity, and entered directly the optic dural sheath, thus no part of the OA was visible in the cranial cavity. OApassed through the optic canal within the dural sheath of the optic nerve. In 44% of our specimens the OAwas on the inferomedial side of the optic nerve at the entrance point to the optic canal. OAleft the optic canal at its lateral border in the apex of the orbit in 72% of our specimens. For descriptive purposes the intraorbital course of the ophthalmic artery has been divided into three parts. The first part usually runs along the infero lateral aspect of the optic nerve. The second part crosses over (in 88%) or under the optic nerve running in a medial direction. The third part extends medially to its termination. These anatomical data may provide important information for understanding the variety of the pathology in this region and is also useful for designing operative strategies.