Dijabetes melitus tip 2 je jedno od vodećíh hroničnih oboljenja u svetu pa i u našoj zemlji, koje predstavlja
značajan faktor rizika u nastanku kardiovaskularnog morbiditeta i mortaliteta. Cilj ovog istraživanja je ispitivanje koji
faktori rizika doprinose nastanku koronarne bolesti kod gojaznih pacijenata sa dijabetes melitusom tip 2. U studiju je
uključeno 82 gojazna pacijenta, od toga 52 sa dijabetes melitusom i 30 bez dijabetes melitusa, sa angiografski dokazanom koronarnom bolešću. Kod svih je sprovedeno kliničko ispitivanje, laboratorijske analize i ehokardiografski pregled. Na osnovu rezultata ispitivanja utvrdili smo da je distribucija faktora rizika kao što su arterijska hipertenzija,
porodično opterećenje koronarnom bolešću, pušenje, konzumacija alkohola bila istovetna u gojaznih pacijenata sa i
bez dijabetes melitusa. Ehokardiografki je nađena statistički značajno veća leva komora, niža ejekciona frakcija, veća
leva pretkomora i značajna mitralna regurgitacija u grupi sa dijabetesom. U grupi sa dijabetesom je takođe češće,
statistički značajno, bila prisutna višesudovna koronarna bolest. Uprkos malom uzorku može se zaključiti da je prisustvo dijabetes melitusa kod gojaznih pacijenata presudno u nastanku težih oblika koronarne bolesti. Težina se ispoljila kroz značajnije strukturne i funkcionalne promene leve komore i broj obolelih koronarnih arterija.  

Miksofibroliposarkom je miksoidni mekotkivni tumor. Za postavljanje tacne dijagnoze, potrebno je da se drzimo
nekoliko kriterijuma, uglavnom patoloskih. Najvazniji je,svakako, pleomorfozam sa celijskom atipijom izrazenom u,
najmanje,10% tkiva..Većina nastaje u površnim slojevima potkožnog tkiva ili u dermisu. Jasna razlika izmedju low
grade MFLSa i high grade MFLSa nije jasna. Medjutim, rekurentni low grade miksofibroliposarkom je infiltrativan, a
zna da bude vrlo agresivan.Tako metastatske tumore mozemo naci u mezenterijumu,plucima,bubrezima,pleuri i
kostima,i drugim udaljenim organima. Ovakva vrsta tumora vrlo je cesta u donjim ekstremitetima starijih pacijenata.Prognoza i terapija varira od slučaja do slučaja. Lečenje je hirurško a ponekad podrazumeva i hemioterapiju i zračenje. 

The aim of this study was to evaluate the diagnostic accuracy of ischemia modified albumin (IMA) alone, or in combination with cardiac troponin T (cTnT) and electrocardiogram (ECG) findings for diagnosis of acute coronary syndrome (ACS). The study included patients with acute chest pain suggestive on ACS, recruited within 6 hours from onset. Patients were classified in ACS group and non-ischemic chest pain group (NICP). Of 84 patients, 49 were diagnosed with ACS and 35 with NICP. IMA was significantly higher in ACS group (p<0.0001). The area under receiver operating curve for IMA in ACS diagnosis was 0.95 (p<0.0001). Sensitivity and specificity of IMA for ACS diagnosis were 89.8% and 91.4%, respectively. IMA significantly (p<0.05) improved the sensitivity of ECG and cTnT, alone, and in combination. Sensitivity and negative predictive value of combination of IMA, ECG and cTnT for diagnosis of ACS were 100%. IMA is useful for diagnosis of ACS, in combination with ECG and cTnT.

Involuntary hospitalization for treatment of mental patients is a necessity in modern scientific psychiatric practice. Hospitalization is generally an act of psychological and social disruption of individual’s homeostasis, which is a very important and complex problem for the mentally ill. The goal of the study was to confirm the necessity of involuntary treatment of mental patients in a medical institution, in the interest of patients and the society. The research was conducted as a cross sectional study of hospitalized patients in 2012 at the Clinic for psychiatric disorders "Dr Laza Lazarevic" in Belgrade. It included 2286 inpatients, especially involuntarily hospitalized 236 and 719 admitted for hospital treatment with the assistance of the police. The data were statistically analysed by methods of descriptive statistics: χ2 - test and multiple logistic regression analysis, using the software package SPSS v. 20. The results show that 255 patients were admitted to the hospital for the first time with the assistance of the police. Patients hospitalized with the assistance of the police in compared to those hospitalized without the assistance of the police were, with statistical significance: younger, more frequently males, most frequently in the diagnostic group of schizophrenia and less frequently in the group of organic and affective disorders, most often it was their first, and involuntary hospitalization. During the studied period, 236 (10%) of the total number treated patients were involuntarily hospitalized. There were 176 (74.58%) patients detained for treatment by force, with the assistance of police. There is a necessity for involuntary hospitalization of mental patients. The justification of detaining patients in the health institution by such measures is accomplished through legislation in the best interest of the patient.

U radu je prikazana žena stara 73 godine koja je hospitalizovana u jedinicu Intenzivne nege zbog osećaja nedostatka vazduha i atpičnog diskomfora u grudima unazad dva sata. Krvni pritisak na prijemu je bio veoma povišen (240/130 mmHg), kardijalni troponin i iznad referentnih vrednosti (2,1 ng/ml) a inicijalni EKG zapis bio je sugestibilan za infarkt miokarda bez ST elevacije. Ehokardiografska evaluacija i koronarna arteriografija koje su usledile isključile su akutni koronarni sindrom kao uzrok povećanog kardijalnog troponina.

Number of poisons which surround the modern man is constantly on the rise and hence therefore the frequency of intoxication. The aim of the study was to determine the type of poison which causes the suicidal poisoning, sex, age, occupation, place of poisoning, events and seasonal distribution of poisoned. This paper analyzes the suicidal poisoning, autopsied at the Institute of Forensic Medicine in Belgrade in two periods (1965-1969) and (2000-2004) years . To test for statistical significance was used Pearson's X2 test. Comparative analysis of the obtained results shows that a significantly more frequent suicidal poisoning in the first analyzed period (1965-1969), P<0.01 compared to the second (2000-2004) In the first research period, the suicidal purposes are often used caustic poisons (44.0%) and drugs (36.4%) with a slight dominance of the older age groups among the poisoned. According to the frequency of poisoning drugs no statistically significant differences in the analyzed periods (x2=0.248 , df=1, p=0.6) . In second research period, significantly dominated by males (79.5%) (x2=33.911 , df=1, p<0.0001), younger age groups (20-49 years , 86.99%), which were poisoned significantly more frequent in spring and summer (55%) compared to the first period. In both studied periods had no significant statistical difference in relation to occupation, place of poisoning and the clinical picture. The highest percentage of deaths (servants and housewives) in both periods were without clinical picture, because they were found dead in their own homes. Length of outliving period of several hours is significantly higher in the second examined period, because of application of more sophisticated, more toxic and simple to use poisons.

Sindrom opstrukcijske apneje u spavanju (SOAS) je poremećaj disanja u kome se javlja delimična ili potpuna opstrukcija gornjih disajnih puteva, što ometa normalnu ventilaciju pluća i tako remeti normalan obrazac spavanja. Klinički se ispoljava habitualnim hrkanjem, često udruženim sa zastojem u disanju, i znacima napornog disanja tokom spavanja, kao i različitim neurobihejvioralnim problemima koji se javljaju tokom dana. Neprepoznat i nelečen SOAS može dovesti do trajnih, pa i životno opasnih posledica. Svaki pacijent sa smetnjama disanja vezanim za spavanje trebalo bi da bude podvrgnut polisomnografskom ispitivanju tokom noći.

Oštećena tolerancija glukoze,pojam poznat kao predijabetes , predstavlja stepenicu ispred razvoja dijabetes mellitusa tip 2 i može se javiti i deceniju pre manifestnog oblika dijabetesa i sve je češći u mlađoj populaciji. Cilj rada bio je da utvrdi uticaj fizicke neaktivnosti na pojavu predijabatesa i dijabetes mellitusa tip 2. Obrađeno je 80 bolesnika u endokrinološkoj ambulanti Interne klinike KBC Priština-Gračanica, u Lapljem Selu.Ispitanici su anketirani uputnikom iz vodiča Nacionalnog programa za prevenciju dijabetesa tip 2 Republike Srbije. Svim ispitanicima su odrađene polne, demografske i antropometrijske karakteristike kao istepen intolerancije glukoze. Od 80 pacijenata, 33 (41,25%) su muškog pola, a 47 (58,75%) su ženskog pola. Nema statističke značajnosti Hi² testa raspodele ispitanika prema familijarnoj anamnezi (=0,007, p>0,05). Fizička neaktivnost je registrovna u 16 ispitanika (20%), a ostalih 64 ispitanika je fizički aktivno. Normalna glikemija natašte u fizički neaktivnih ispitanika je bila u 56,25% (9), a glikemiju veću od 7 mmol/l je imalo 18,75% ispitanika. Pozitivan OGTT nalaz kod fizički neaktivnih ispitanika je potvrđen u 62,5% , a pozitivan OGTT nalaz kod fizički aktivnih je registrovan u samo 5 ispitanika (11,36%). Ispitanici sa rizikom za nastanak dijabetesa tip 2 (skor 12 i više) u 60% su bili fizički neaktivni. Umerena fizička aktivnost uz korekciju telesne mase ,može znatno da „odloži“ nastanak dijabetes mellitus-a tip 2.

Gastrointestinal stromal tumors (GIST omi) are a heterogeneous group of mesenchymal tumors. Etiological factors that cause GIST ome are not clearly distinguished, characterized by remarkable diversity of the clinical, histopathological and genetic features. Mitotic activity, nuclear pleomorphism, degree of cellularity, nuclear-cytoplasmic ratio, tumor size, mucosal invasion, tumor ulceration and necrosis, are factors that determine the malignancy of these tumors. The most common location of these tumors of the stomach and small intestine, while very rare localization of the colon, esophagus and rectum. Despite the progress that has been made in the diagnosis and further diagnosis of intra - or postoperative. The aim of this report is to contribute to easier recognizing the symptoms, diagnosis and treatment of these tumors. It was a mixed tumor, epitheloid-spindle type cells, immunohistochemical analysis, we have a positive expression of CD 117 and CD 34.

Instrumenti kvaliteta života specifični za dermatologiju, sve češće se primenjuju u istraživanju kod pacijenata sa kožnim bolestima. CIlj je ispitati odnos ocena kvaliteta života dobijenih primenom dva za dermatologiju specifična instrumenta. Istraživanjem je obuhvaćeno 62 ispitanika sa kožnim bolestima, kod kojih je kvalitet života ocenjen primenom instrumenata specifičnih za dermatologiju (tj. Dermatology Life Quality Index-DLQI i Skindex-16), namenjenih upotrebi kod svih kožnih bolesti. Ukupni skorovi DLQI i Skindex-16 nalazili su se u jakoj korelaciji (r=0.87; p<0.001). Postojale su i statistički značajne korelacije ukupnog skora DLQI sa skorovima za podskale simptomi, emocije i funkcionisanje iz Skindex-16 instrumenta (r=0.53, r=0.77 i r=0.86, redom). Ukupan skor Skindex-16 nije bio u korelaciji sa skorom za podskalu tretman iz DLQI-a, međutim, bio je u korelaciji sa skorovima za podskale simptomi i osećanja, dnevne aktivnosti, slobodne aktivnosti, rad ili škola i lični odnosi iz DLQI-a (r=0.67, r=0.80, r=0.66, r=0.62 i r=0.68, redom). Dva instrumenta specifična za dermatologiju (npr. DLQI i Skindex-16), ukoliko se zajedno primenjuju, mogu pružiti komplementarne podatke pri ocenjivanju kvaliteta života pacijenata sa kožnim bolestima.