Dijabetes melitus tip 2 je jedno od vodećíh hroničnih oboljenja u svetu pa i u našoj zemlji, koje predstavlja značajan faktor rizika u nastanku kardiovaskularnog morbiditeta i mortaliteta. Cilj ovog istraživanja je ispitivanje koji faktori rizika doprinose nastanku koronarne bolesti kod gojaznih pacijenata sa dijabetes melitusom tip 2. U studiju je uključeno 82 gojazna pacijenta, od toga 52 sa dijabetes melitusom i 30 bez dijabetes melitusa, sa angiografski dokazanom koronarnom bolešću. Kod svih je sprovedeno kliničko ispitivanje, laboratorijske analize i ehokardiografski pregled. Na osnovu rezultata ispitivanja utvrdili smo da je distribucija faktora rizika kao što su arterijska hipertenzija, porodično opterećenje koronarnom bolešću, pušenje, konzumacija alkohola bila istovetna u gojaznih pacijenata sa i bez dijabetes melitusa. Ehokardiografki je nađena statistički značajno veća leva komora, niža ejekciona frakcija, veća leva pretkomora i značajna mitralna regurgitacija u grupi sa dijabetesom. U grupi sa dijabetesom je takođe češće, statistički značajno, bila prisutna višesudovna koronarna bolest. Uprkos malom uzorku može se zaključiti da je prisustvo dijabetes melitusa kod gojaznih pacijenata presudno u nastanku težih oblika koronarne bolesti. Težina se ispoljila kroz značajnije strukturne i funkcionalne promene leve komore i broj obolelih koronarnih arterija.
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