MIKSOFIBROLIPOSARKOM I KARAKTERISTIKE TUMORA

Maja Nikolic-Zivanovic ,
Maja Nikolic-Zivanovic
R. Grbic
R. Grbic

Published: 01.12.2013.

Volume 43, Issue 4 (2014)

pp. 85-87;

https://doi.org/10.5937/pramed1404085n

Abstract

Miksofibroliposarkom je miksoidni mekotkivni tumor. Za postavljanje tacne dijagnoze, potrebno je da se drzimo
nekoliko kriterijuma, uglavnom patoloskih. Najvazniji je,svakako, pleomorfozam sa celijskom atipijom izrazenom u,
najmanje,10% tkiva..Većina nastaje u površnim slojevima potkožnog tkiva ili u dermisu. Jasna razlika izmedju low
grade MFLSa i high grade MFLSa nije jasna. Medjutim, rekurentni low grade miksofibroliposarkom je infiltrativan, a
zna da bude vrlo agresivan.Tako metastatske tumore mozemo naci u mezenterijumu,plucima,bubrezima,pleuri i
kostima,i drugim udaljenim organima. Ovakva vrsta tumora vrlo je cesta u donjim ekstremitetima starijih pacijenata.Prognoza i terapija varira od slučaja do slučaja. Lečenje je hirurško a ponekad podrazumeva i hemioterapiju i zračenje. 

Keywords

References

1.
Waters B, Panicek D, Lefkowitz R, Antonescu C, Healey J, Athanasian E, et al. Low-Grade Myxofibrosarcoma: CT and MRI Patterns in Recurrent Disease.
2.
Stanford RVRMR.
3.
Mansoor A, White C. Myxofibrosarcoma presenting in the skin: clinicopathological features and differential diagnosis with cutaneous myxoid neoplasms. Am J Dermatopathol. 2003;281–6.
4.
Tateishi U, Hasegawa T, Onaya H, Satake M, Arai Y, Moriyama N. Myxoinflammatory fibroblastic sarcoma: MR appearance and pathologic correlation. AJR. 2005;1749–53.
5.
Fujimura T, Okuyama R, Terui T, Okuno K, Masu A, Masu T, et al. Myxofibrosarcoma (myxoid malignant fibrous histiocytoma) showing cutaneous presentation: report of two cases. J Cutan Pathol. 2005;(7):512–5.
6.
Wada T, Hasegawa T, Nagoya S, Kawaguchi S, Kaya M, Ishii S. Myxofibrosarcoma with an infiltrative growth pattern: a case report. Jpn J Clin Oncol. 2000;(10):458–62.
7.
Willems S, Debiec-Rychter M, Szuhai K, Hogendoorn P, Sciot R. Local recurrence of myxofibrosarcoma is associated with increase in tumour grade and cytogenetic aberrations, suggesting a multistep tumour progression model. Mod Pathol. 2006;(3):407–16.

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