Quality of life (QoL) is used in the natural and social sciences as a relatively new category which deserves more attention in research. Quality of life related to health is a term commonly used when QoL on health. An increasing number of research studies that are based on an examination of the QoL. This paper analyzes the concept of the QoL, the possibilities of measuring the QoL, a special emphasis is placed on measuring QoL in dermatovenereology. Given that the skin disease are of particular significance for the patient, the said indices are dermatologically quality of life, especially the quality of life of patients dermatological (DLQI).

Introduction: In adults the diagnosis of acute pyelonephritis and glomerulonephritis is primarily based on clinical and laboratory-biochemical testing. In patients where the clinical picture atypical, even if a person does not respond to therapy resorts to radiographic examination. Echotomographic examination is unavoidable in the diagnostic algorithm. Objective: The aim of this study was to establish the individual echotomographic parameters, as well as to determine their diagnostic power in patients with acute infections (pyelonephritis and glomerulonephritis), and comparing them with the appropriate reference tests. Materials and methods: We performed a cross sectional study in the period from October 2014. until May 2015. It included 50 patients with acute inflammation of the kidney which was made echotomographic examination of the abdomen and pelvis, within the Department of Radiological Diagnostics KBC "Dragisa Mišović-Dedinje" in Belgrade. The echotomographic examination of the kidneys included testing of numerous parameters that could indicate the existence of an acute inflammation of the kidney. For the gold standard, we take the findings obtained by CT (computed tomography) imaging of the abdomen and pelvis, as well as histopathological findings obtained by fine needle bio-psy. Results: At 50 patients with acute inflammation of the upper urinary tract, 41 patients (82%) had acute pyelonephritis, and 9 (18%) had acute glomerulonephritis. In 70% of patients with acute pyelonephritis (29 people) were present enlargement of the kidney where the test sensitivity was 79.3% and specificity of 91.7%. The accuracy of the method was 82.9% when the monitored parameters: loss of central echo complex and cortico-medullary differentiation. The sensitivity of the test in which the observed thickening of the pelvic and ureteric wall was 65% and specificity of 90%. The analysis of the presence of calculus in renal parenchyma leads to the values of sensitivity test of 54.8% and specificity of 80%. Hypoechoic focus in the renal parenchyma, enlargement of the kidneys and loss corticomedullar limits are parameters who with great sensitivity and specificity suggest acute glomerulonephritis. Conclusion: On the basis of high values of sensitivity and specificity of the test survey estimates that ultrasound has a required place in the following diagnostics algorithm. The use of echotomography that offer the possibility of high resolutive views, as well as the wide availability and good reproducibility of the method, the low cost of inspection, in favor of the first exploration ultrasound examination. Multidetector CT scan and fine needle biopsy remains the method of choice for the definitive diagnosis.

U radu je prikazana žena stara 73 godine koja je hospitalizovana u jedinicu Intenzivne nege zbog osećaja nedostatka vazduha i atpičnog diskomfora u grudima unazad dva sata. Krvni pritisak na prijemu je bio veoma povišen (240/130 mmHg), kardijalni troponin i iznad referentnih vrednosti (2,1 ng/ml) a inicijalni EKG zapis bio je sugestibilan za infarkt miokarda bez ST elevacije. Ehokardiografska evaluacija i koronarna arteriografija koje su usledile isključile su akutni koronarni sindrom kao uzrok povećanog kardijalnog troponina.

Sindrom opstrukcijske apneje u spavanju (SOAS) je poremećaj disanja u kome se javlja delimična ili potpuna opstrukcija gornjih disajnih puteva, što ometa normalnu ventilaciju pluća i tako remeti normalan obrazac spavanja. Klinički se ispoljava habitualnim hrkanjem, često udruženim sa zastojem u disanju, i znacima napornog disanja tokom spavanja, kao i različitim neurobihejvioralnim problemima koji se javljaju tokom dana. Neprepoznat i nelečen SOAS može dovesti do trajnih, pa i životno opasnih posledica. Svaki pacijent sa smetnjama disanja vezanim za spavanje trebalo bi da bude podvrgnut polisomnografskom ispitivanju tokom noći.

Apert syndrome is named for the French physician, Eugen Apert who was, in 1906. described anomalous shape of the skull with coronary suture synostosis and hypoplasia sphenoethmoidmaxillary part of the face and fingers syndactyly of hands and feet. Apert syndrome accounts for about 4,5% of all craniosynostosis. With the prevalence of 1:160 000-200 000, inherited in an autosomal dominant, and in 25% of cases are fresh mutations in the gene. This syndrome has no predilection by gender and race, varies in severity form in witch it is manifested. Anomality of internal organs are very rare, but half of the patients with this syndrome have mental retardation. Apert syndrome has no cure, but surgery can help to correct some of the problems. 

Prikaz slučaja bolesnice sa Astrocitomom u predelu parahipokampalne regije leve hemisfere kod koga je nakon
resekcije levog temporalnog režnja došlo do razvoja shizofreniformne psihoze. Psihički i neurološki status, Skala za
procenu pozitivnog i negativnog sindroma shizofrenije (PANSS), Mini internacionalni neuropsihijatrijski intervju (MINI) ,
verzija 4,4., subkategorija N za psihotične sadržaje, Šihanova skala narušavanja sposobnosti (SSNS), Hamiltonova
skala za procenu depresije Hamiltonova skala zaprocenu anksioznosti, Montgomeri-Asberg skala za depresiju, elektroencefalogram (EEG), standardno i registrovanje nakon deprivacije spavanja, kompjuterizovanatomografija glave
(CT) i neuromagnetna rezonanca endokranijuma (NMR). Bolesnica stara 51 godinu, od 12-te godine života ima epileptičke napade, koji su definisani kao jednostavni i složeni žarišni u vidu zagledanja, motornih ambulatornih automatizama sa retkom sekundarnom generalizacijom i postiktalnom zbunjenosti. Nakon što je učinjen NMR endokranijuma
kojim je utvrdjen tumor u levoj parahipokampalnoj formaciji, uradjena resekcija levog temporalnog režnja, gde je
patohistološki utvrdjeno da se radi o Astrocitomu II stepena. Nakon intervencije došlo do razvoja polimorfne simptomatologije, sa dominacijom paranoidno-depresivne simptomatologije i epileptičkih napada sa aurom straha, spaciotemporalnom dezorijentacijom i gubitkom svesti. Pacijentkinja tretirana racionalnom antiepileptičkom politerapijom
i neurolepticima nakon čega je došlo do kliničkog poboljšanja slike psihoze i smanjenja učestalosti epileptičkih napada. Nakon temporalne lobektomije došlo je do razvoja „de novo psihoze“ sa kliničkom slikom shizofreniformne epileptičke psihoze.  

One of possibilities to estimate size of myocardial injury during the acute myocardial infarction are electrocardiographic changes,
forming of QS formation (ECG signs of scares changes). This investigation which included three groups of patients receiving thrombolytic, nitrates or beta blockers in acute phase of myocardial infarction has aim to analyze 12-chanels electrocardiogram and to establish difference between this therapeutics groups in sum of QRS score, but also to indicateon frequency of periinfarction heart insufficiency in this therapeutics groups, comparing with observed ECG changes. Analysis shows significant differences between groups
in value of QRS score, and also significant lower value of QRS score in patients with acute myocardial infarction treated with thrombolytic therapy. This difference relative to other two groups shows lower level of myocardial injury during acute myocardial infarction in patients treating with thrombolytic therapy. 

Development of accessory breast tissue is a consequence the lack of regression remanths of milk line during embryogenesis. These remanths can be found anywhere on the ventral side of the body, extending from the axilla to the pubic region and most of them can be found in the axillary region. On such a tissue may appear almost identical changes that affect the normal breast, from benign non-tumor changes to malignant tumors. In our case report, the case is a 23 year-old woman who had a unilateral solitary lesions in the axilla, which was surgically removed. Starting diagnosis was " Limphadnopathia axillaris lateris sinistri." After removal and histopathological evaluation of the change, it was found that there is a tumor - fibroadenoma. There were also performed immunohistochemical ( IHH ) staining, with finding of a conventional fibroadenoma of the breast as expected. Accessory breast tissue in the axilla is a rare finding, and the tumors in this tissue even rarer. Histopathological confirmation is mandatory, with the need to exclude malignant tumors which are more common in these cases, and they occur at an earlier age.

Prognoza i izbor terapije adenokarcinoma prostate (ADKP) direktno zavise od brojnih prediktivnih faktora, među kojima su najznačajniji zbirni histološki gradus tumora (Gleason score, koji predstavlja zbir prvog i drugog dominantnog histološkog gradusa) i klinički stadijum. Novija istraživanja u ove faktore ubrajaju i tkivni androgen status i neuroendokrinu diferencijaciju. Važnost prvog i drugog dominantnog histološkog gradusa naročito postaje značajan kod ADKP Gleason score-a 7. Smatra se da goru prognozu imaju ADKP višeg Gleason score-a, uznapredovalog kliničkog stadijuma, androgen nezavisni tumori i tumori koji pokazuju veći stepen neuroendokrine diferencijacije. Cilj rada je odrediti prediktivni značaj ADKP Gleason score-a 7 (3+4) i ADKP Gleason score-a 7 (4+3) u odnosu na klinički stadijum, tkivni androgen status i stepen fokalne neuroendokrine diferencijacije. Istraživanje je obuhvatilo 33 ADKP Gleason score-a 7, odnosno 26 (78,79%) ADKP 7 (3+4) i 7 (21,21%) ADKP 7 (4+3). Svi tumori su najčešće dijagnostikovani u stadijumu D2 kada su već postojale udaljene metastaze. ADKP Gleason score-a 7 (4+3) dijagnostikovani su u većem procentu u ovom stadijumu, među njima ima više androgen nezavisnih tumora i pokazuju veći stepen fokalne neuroendokrine diferencijacije. Svi dobijeni rezultati u saglasnosti su sa podacima iz literature i navode na zaključak da ADKP Gleason score-a 7 (4+3) imaju goru prognozu od ADKP Gleason score-a 7 (3+4).

Involuntary hospitalization for treatment of mental patients is a necessity in modern scientific psychiatric practice. Hospitalization is generally an act of psychological and social disruption of individual’s homeostasis, which is a very important and complex problem for the mentally ill. The goal of the study was to confirm the necessity of involuntary treatment of mental patients in a medical institution, in the interest of patients and the society. The research was conducted as a cross sectional study of hospitalized patients in 2012 at the Clinic for psychiatric disorders "Dr Laza Lazarevic" in Belgrade. It included 2286 inpatients, especially involuntarily hospitalized 236 and 719 admitted for hospital treatment with the assistance of the police. The data were statistically analysed by methods of descriptive statistics: χ2 - test and multiple logistic regression analysis, using the software package SPSS v. 20. The results show that 255 patients were admitted to the hospital for the first time with the assistance of the police. Patients hospitalized with the assistance of the police in compared to those hospitalized without the assistance of the police were, with statistical significance: younger, more frequently males, most frequently in the diagnostic group of schizophrenia and less frequently in the group of organic and affective disorders, most often it was their first, and involuntary hospitalization. During the studied period, 236 (10%) of the total number treated patients were involuntarily hospitalized. There were 176 (74.58%) patients detained for treatment by force, with the assistance of police. There is a necessity for involuntary hospitalization of mental patients. The justification of detaining patients in the health institution by such measures is accomplished through legislation in the best interest of the patient.