Chronic kidney disease (CKD) is a syndrome which is caused by gradual progressive and irreversible reduction of kidney function. CKD has become a global health care problem. From a mental hygiene point of view, the aim of this study is to present the most important stressors in patients with CKD. Knowledge and recognition of everything that influences the increase of stress in people with CKD, on one hand leads to an improvement of understanding , and on the other gives us possibilities to prevent or at least reduce the negative effects of stress. Furthermore, patients with CKD often have anxiety and depressive symptoms which overlap with the clinical symptomatology of kidney disease, which is mostly caused by uremia. We have given certain suggestions for early depression screening in patients with CKD by analyzing previously conducted research. As far as diet is concerned, research suggests that patients with CKD should be prescribed a low protein diet which delays the progression of CKD, reduces the metabolical disbalance and delays the need for dialysis. A traditional diet focused on protein intake without a special selection of meals is recommended. Other recommendations are vegan diet as well as vegan diet with suplements. Furthermore, a diet without proteins with pastas without proteins, bread and other carbohydrates. There are also recommendations for a low protein diet with suplements with an intake of only 0.3 g/kg BM/protein a day with an addition of proteins from vegetables, amino and keto acids. Finally, it should be mentioned that comorbidities should be taken into consideration when prescribing a diet for patients with CKD. It is necessary for the patient to be compliant with the recommended diet.
Eknoyan G, Lameire N, Barsoum R, Eckardt K, Levin L, N. The burden of kidney disease: improving global outcomes. Kidney Int. 2004;1310–4.
2.
Go A, Chertow G, Fan D, Mcculloch C, Hsu C. Chronic kidney disease and the risks of death, car¬diovascular events, and hospitalization. N Engl J Med. 2004;1296–305.
3.
Lina C, Weilinaa J. Association of Framingham Risk Score with chronic kidney disease: insight from National Health and Nutrition Examination Survey 2003-2006. Kidney Res Clin Pract. 2012;A52.
4.
Oh Y, Cha R, Lee S, Yu K, Kim S, Kim H. Validation of the Korean coefficient for the modification of diet in renal disease study equation. The Korean Journal of Internal Medicine. 2016;(2):344–56.
5.
Locatelli F, Vecchio L, Pozzoni P. The importance of early detection of chronic kidney disease. Nephrol Dial Transplant. 2002;(11):2–7.
6.
Fogo A. Progression versus regression of chronic kidney disease. Nephrol Dial Transplant. 2006;(2):281–4.
7.
Cukor D, Cohen S, Peterson R, Kimmel P. Psychosocial aspects of chronic disease: ESRD as a paradigmatic illness. J Am Soc Nephrol. 2007;3042–55.
8.
Mirković M, Đurić S, Milošević J, Ilić D, Milić M. Javno-zdravstveni aspekti poremećaja mentalnog zdravlja. Praxis Medica. (3–4):73–7.
9.
Hedayati S, Yalamanchili V, Finkelstein F. A practical approach to the treatment of depression in patients with chronic kidney disease and end-stage renal disease. Kidney Int. 2012;(3):247–55.
10.
Kdoqi.
11.
Braunwald E, Fauci A, Hauser S, Longo D;, Dennis L, Kasper. Harrison principles of internal medicine. The 16th edition. 2004;
12.
Davison A, Cameron S, Grunfeld J, Ponticelli C, Ritz E, Winearls C, et al. 2005;
13.
K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis. 2002;(2):1–266.
14.
Bolton W, Kliger A. Chronic renal insufficiency: current understandings and their implications. Am J Kidney Dis. 2000;(6):4–12.
15.
Stojimirović B, Petrović D. Clinical significance of risk factors control in prevention of chronic renal failure progression. Vojnosanit Pregl. 2006;(6):585–91.
16.
Turkistani I, Nuqali A, Badawi M, Taibah O, Alserihy O, Morad M. The prevalence of anxiety and depression among endstage renal disease patients on hemodialysis in Saudi Arabia. Ren Fail. 2014;(10):1510–5.
17.
Grigoriou S, Karatzaferi C, Sakkas G. Pharmacological and Non-pharmacological Treatment Options for Depression and Depressive Symptoms in Hemodialysis Patients. Health Psychol Res. 2015;(1):1811.
18.
Knežević M, Jović J, Đorđević V, Ristić I, Đorđević D, V. Depresivnost kod pacijenata na hroničnoj hemodijalizi. Medicinski časopis. 2012;38.
19.
Knežević M. Analiza faktora koji utiču na mentalno zdravlje pacijenata na hemodijalizi. 2014;
20.
Levy N. What is psychonephrology? J Nephrol. 2008;51–3.
21.
Knezevic M, Djordjevic V, Bivolarevic I, Jovic J, Djordjević V. Insomnia severity in chronic kidney disease patients with various therapies. Central European Journal of Medicine. 2012;(1):112–7.
22.
Sladojević N, Knežević M, Jović J, Đorđević V. Sindrom nemirnih nogu kod pacijenata na hemodijalizi -učestalost, težina i faktori rizika. Medicinski časopis. 2012;(3):138–44.
23.
Johnson S, Dwyer A. Patient perceived barriers to treatment of depression and anxiety in hemodialysis patients. Clin Nephrol. 2008;201–6.
24.
Palmer S, Vecchio M, Craig J, Tonelli M, Johnson D, Nicolucci A. Association between depression and death in people with CKD: a meta-analysis of cohort studies. Am J Kidney Dis. 2013;(3):493–505.
25.
Vasilopoulou C, Bourtsi E, Giaple S, Koutelekos I, Theofilou P, Polikandrioti M. Global Journal of Health Science. 2016;(1):45–55.
26.
Ćorac A.
27.
Mitrovica K. 2007;
28.
Hays R, Sherbourne C, Mazel R. The RAND 36-Item Health Survey 1.0. Health Econ. 1993;(3):217–27.
29.
Ristić I, Hinić D, Jović D, J. Evaluation of the beck depression inventory in nonclinical student sample. West Indian Med J. 2012;(5):489–93.
30.
Stolić D, Jović J, Bukumirić Z, Rančić N, Stolić M, Ignjatović-Ristić D. The Serbian version of the geriatric depression scale: reliability, validity and psychometric features among the depressed and non-depressed elderly. Engrami. 2015;(4):51–64.
31.
Giovannetti S, Maggiore Q. A low nitrogen diet with proteins of high biological value for severe chronic uremia. Lancet. 1964;1000–3.
32.
Addis T. Glomerular nephritis: Diagnosis and treatment. 1949;
33.
Piccoli G. Patient-based continuum of care in nephrology: why read Thomas Addis’ “Glomerular Nephritis” in 2010? J Nephrol. 2010;164–7.
34.
Borst J. Protein katabolism in uraemia; effects of protein-free diet, infections, and blood-transfusions. Lancet. 1948;824–9.
35.
Millward D, Jackson A. Protein/energy ratios of current diets in developed and developing countries compared with a safe protein/energy ratio: implications for recommended protein and amino acid intakes. Public Health Nutr. 2004;387–405.
36.
Volpi E, Campbell W, Dwyer J. Is the optimal level of protein intake for older adults greater than the recommended dietary allowance? J Gerontol A Biol Sci Med Sci. 2013;677–81.
37.
Kitsios G, Kent D. Personalised medicine: not just in our genes. BMJ. 2012;2161.
38.
Basch E. Toward patient-centered drug development in oncology. N Engl J Med. 2013;397–400.
39.
Lin G. Patient education: one size does not fit all. JAMA Intern Med. 2013;1376.
40.
Black N. Why we need observational studies to evaluate the effectiveness of health care. BMJ. 1996;1215–8.
41.
Piccoli G, Capizzi I, Vigotti F, Leone F, ’alessandro D, Giuffrida C, et al. Low protein diets in patients with chronic kidney disease: a bridge between mainstream and complementary-alternative medicines? BMC Nephrology. 2016;76.
42.
Bellizzi V, Cupisti A, Locatelli F, Bolasco P, Brunori G, Cancarini G. Low-protein diets for chronic kidney disease patients: the Italian experience. BMC Nephrol. 2016;(1):77.
43.
Kanazawa Y, Nakao T, Ohya Y, Shimomitsu T. Association of socio-psychological factors with the effects of low protein diet for the prevention of the progression of chronic renal failure. Intern Med. 2006;(4):199–206.
44.
Cianciaruso B, Pota A, Pisani A. Metabolic effects of two low protein diets in chronic kidney disease stage 4-5-a randomized controlled trial. Nephrol Dial Transplant. 2008;636–44.
45.
Garneata L, Stancu A, Dragomir D, Stefan G, Mircescu G. Ketoanalogue-Supplemented Vegetarian Very Low-Protein Diet and CKD Progression. J Am Soc Nephrol. 2016;(7):2164–76.
46.
Brunori G, Viola B, Parrinello G. Efficacy and safety of a very-low-protein diet when postponing dialysis in the elderly: a prospective randomized multicenter controlled study. Am J Kidney Dis. 2007;569–80.
47.
Klahr S, Levey A, Beck G. The effects of dietary protein restriction and blood-pressure control on the progression of chronic renal disease. Modification of Diet in Renal Disease Study Group. N Engl J Med. 1994;877–84.
48.
Levey A, Greene T, Beck G, Caggiula A, Kusek J, Hunsicker L. Dietary protein restriction and the progression of chronic renal disease: What have all of the results of the MDRD study shown? J Am Soc Nephrol. 1999;2426–39.
49.
Kopple J, Greene T, Chumlea W. Relationship between nutritional status and the glomerular filtration rate: results from the MDRD study. Kidney Int. 2000;1688–703.
50.
Viberti G, Bognetti E, Wiseman M, Dodds R, Gross J, Keen H. Effect of protein-restricted diet on renal response to a meat meal in humans. Am J Physiol. 1987;(3):388–93.
51.
Bernhard J, Beaufrere B, Laville M, Fouque D. Adaptive response to a low protein diet in predialysis chronic renal failure patients. J Am Soc Nephrol. 2001;(6):1249–54.
52.
Marinela K, Vladimir Đ, Žilijeta K, Jelena J, Vidojko Đ. Fizička aktivnost i mentalno zdravlje kod pacijenata na hemodijalizi. Medicinski. 2013;
53.
Schmitz P. Progressive renal insufficiency. Office strategies to prevent or slow progression of kidney disease. Postgrad Med. 2000;(1):145–8.
54.
Rossert J, Wauters J. Recommendations for the screening and management of patients with chronic kidney disease. Nephrol Dial Transplant. 2002;(1):19–28.
55.
Praga M. Slowing the progression of renal failure. Kidney Int Suppl. 2002;(80):18–22.
56.
Locatelli F, Vecchio D, L. Protein restriction: a revisited old strategy with new opportunities? Nephrol Dial Transplant. 2014;1624–7.
57.
Tom K, Young V, Chapman T, Masud T, Akpele L, Maroni B. Long-term adaptive responses to dietary protein restriction in chronic renal failure. Am J Physiol Endocrinol Metab. 1995;668–77.
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