Uvod. Rak grlića materice predstavlja značajan globalni javno zdravstveni problem i zauzima četvrto mesto po učestalosti među karcinomima kod žena. Cilj rada bio je da istraži percepciju studenata medicine o faktorima rizika za rak grlića materice, kao prema infekciji Humanim papilloma virusom (HPV) i informisanost o HPV vakcini. Materijal i metode. Sprovedena je studija preseka kojom su bili obuhvaćeni studenti četvrte, pete i šeste godine Integrisanih Akademskih Studija (IAS) medicine Medicinskog fakulteta Univerziteta u Nišu. Primnjen je anonmni upitnik koji je distribuiran preko Google platforme. Rezultati. U istraživanju je učestvovao ukupno 361 student ( 21% muškog i 79% ženskog pola). Prosečan broj poena na testu znanja o raku grlića materice iznosio je 17.25±7.92 (min 0–max 30). Srednjoškolsko obrazovanje studenata imalo je značajan uticaj na znanje o faktorima rizika za rak grlića (p<0.001), kao i mesto stalnog prebivališta. Značajno viši skor znanja imali su student iz gradske sredine (p=0.01); studenti čije su majke imale srednje (p=0.002) ili visoko obrazovanje imali su značajno bolje znanje (p<0.001) od onih čije su majke imale osnovno obrazovanje, kao i studenti čiji su očevi imali visoko obrazovanje (p<0.05) u odnosu na očeve srednjeg obrazovanja. Studenti koji su bili srednjeg i visokog imovinskog stanja imali su značajno viši skor znanja (p=0.008) od studenata koji su bili niskog imovinskog stanja. Svi studenti koji su završili srednju školu medicinske struke imali su značajno bolje znanje o HPV infekciji od studenata koji su završili gimnaziju (p<0.001) i škole nemedicinske struke (p<0.001). Studenti koji su bili u partnerskoj vezi (p=0.005) i oni koji su bili seksualno aktivni (p=0.001) imali su značajno bolje znanje o HPV infekciji. Samo 25.5% studenata bilo je svesno značaja HPV vakcinacije u prevenciji raka grlića materice i 16.0% znalo je nešto o HPV vakcini. Visoko obrazovanje majke (p=0.028), parterska veza (p=0.041) i seksualna aktivnost (p=0.001) bili su značajno povezani sa višim nivoom znanja o HPV infekciji. Zaključak. Istraživanje je pokazalo zadovoljavajući da student imaju zadovoljavajući nivo znanja o raku grlića materice, ali je svest o riziku od HPV infekcije i raka grlića materice kao i o prevenciji bila je relativno niska. Ključne reči: rak grlića materice, faktori rizika, studenti medicine, HPV infekcija, prevencija
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