More articles from Volume 37, Issue 2, 2009
FUNCTIONAL ASYMMETRY OF BRAIN AND POTENTIALS P300
INFLUENCE OF DOXORUBICIN ON ELECTRICAL ACTIVITY OF THE MYOCARDIUM AND LEFT VENTRICULAR FUNCTION DURING TREATMENT OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA
MORPHOMETRIC AND STEREOLOGICAL ANALYSIS GANGLION STRUCTURES OF MYENTERIC NERVE PLEXUS, TERMINALLY PART OF HUMAN LARGE INTESTINE
MASSIVENESS OF A SICKNESS, A PATHOGENIC OF CONTAGIUM AND HENLE-KOCH POSTULATES
SOME ASPECTS OF FAMILY PLANNING - FROM MISCARRIAGE TO HEALTH EDUCATION
Citations
0
ADIPOKINES AS FOR RUNNERS OF INFLAMMATORY CITOKINE SUPERFAMILY AND ITS INVOLVEMENT IN INFLAMMATORY AND IMMUNE DISEASES
Medical faculty Priština , Kosovska Mitrovica , Kosovo*
General Hospital Berane Montenegro
Health House Berane Montenegro
Medical faculty , Niš , Serbia
Published: 01.12.2009.
Volume 37, Issue 2 (2009)
pp. 135-141;
Abstract
Leptin was discovered in 1994, finding, that marked the beginning of a new understanding about white adipose tissue. Up to end of 20th century this tissue was viewed as an inert tissue, devoted to body protection from heat loss and to passively store energy. This static vision, changed with identification of the product of the gene obese (ob) wich accentuated the role of adipose tissue in the physiopathology of obesity-linked diseases, and led to the discovery of various adipokines, many of a pro-inflammatory nature. With emerged knowledge of (WAT)-derived adipokines, it is obvious that they can be now considered as the bond between obesity-related environmental causes, such as nutrition and lifestyle, and the biochemical shifts that lead to metabolic syndrome, inflammatory and/or autoimmune conditions, and rheumatic diseases. This paper deals with reviews of recent adipokine research, with particular emphasis to the role of leptin, adiponectin, resistin, and visfatin in chondrocyte function and skeleton, as well as in inflammatory and degenerative cartilage joint diseases.
Keywords
References
Citation
Copyright
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Article metrics
The statements, opinions and data contained in the journal are solely those of the individual authors and contributors and not of the publisher and the editor(s). We stay neutral with regard to jurisdictional claims in published maps and institutional affiliations.
