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RECOMBINANTACTIVATED FACTOR VIIa IN HAEMOSTASIS AFTER RADICALNEPHRECTOMYOFRENOCELULAR CARCINOMA
Medical faculty, Pristina , Kosovska Mitrovica , Kosovo*
Emergency center "Simoinida", Gračanica Bosnia and Herzegovina
Medical faculty, Pristina , Kosovska Mitrovica , Kosovo*
Medical faculty, Pristina , Kosovska Mitrovica , Kosovo*
Medical faculty, Pristina , Kosovska Mitrovica , Kosovo*
Medical faculty, Pristina , Kosovska Mitrovica , Kosovo*
Health center , Kosovska Mitrovica , Kosovo*
Published: 01.01.2007.
Volume 35, Issue 1 (2007)
pp. 117-119;
Abstract
Important facts about recombinant human factor VIIa have been mentioned, also about the renal cell carcinoma. Case report: Male, aged 69, with infiltrative renal cell carcinoma, underwent radical nephrectomy using Hasagawa`s approach. Extirpated tumor had 35 cm in diameter. During the surgery, patient suffered a cardiac arrest with 3500 ml blood loss. After operation, he lost 2100 ml more blood. Despite of active blood supstitutions with intensive surgical attempts in order of haemostasis, bleeding did not stop untill the application of rFVIIa (300 I. U.). Patient survives and recovers completelly. Conclusion: RFVIIa is very succesful in controling of massive surgical bleeding, possibly associated with paraneoplastic syndrome.
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