OUR EXPERIENCE WITH "CHEMET" MEDICATION, FIRST TIME USED IN EUROPE IN KOSOVSKA MITROVICA

J. Živković ,
J. Živković

Medical faculty Priština , Kosovska Mitrovica , Kosovo*

Z. Savić
Z. Savić

Health Centre Kosovska Mitrovica Kosovo*

Published: 01.01.2007.

Volume 35, Issue 1 (2007)

pp. 19-21;

https://doi.org/10.70949/pramed200701171Z

Abstract

In two refugee camps, near K.Mitrovica (in little colliery city), gipsys refugees dislodge by Albanians were temporary located. In their blood, lead contamination is discovered. All together 310 children, 1-14 years old, were contaminated by lead. Examination and treatment is implement by the SZO patronage, which took capillar blood samples from 298 children and vein blood samples from 190 children. Level of lead, in 47 cases was more then 45 microgram./dl. All the children with high level of lead had physical and laboratory tests. Also, they were under special food diet, with a lot of calcium. In 45 cases, per os treatment is used with “Chemet” medication, produced by McNeil-USA.Only in 9 cases, week bad reaction was notice using this medication. In some isolated cases, headache, pain in stomach, sickness and sleepiness. This difficulties didn't required therapy cancelation. Treatment was fully successful except in two cases, where therapy was repeated.

Keywords

References

1.
Graziano JH. Role of 2, 3-dimercaptosuccinic acid in the treatment of heavy metal poisoning. Medical Toxicology. 1(3):155–62.
2.
Kuntzelman DR, Engand KE, Angle CR. Urine lead (UPb) in outpatient treatment of lead poisoning with dimercaptosuccinic acid (DMSA. Veterinary and Human Toxicology. 4:346.
3.
Montalvan J, Okose P, Marcus S. Outpatient chelation therapy of 24 patients with lead intoxication by dimercaptosuccinic acid. Veterinary and Human Toxicology. 4:343.
4.
Rivera M, Zheng W, Aposhian HV, Fernando HQ. Determination and metabolism of dithiol chelating agents. Toxicology and Applied Pharmacology. 100(1):96–106.
5.
Bentur Y, Brook JG, Behar R, Taitelman U. Meso-2,3-dimercaptosuccinic acid in the diagnosis and treatment of lead poisoning. Journal of Toxicology - Clinical Toxicology. 25(1–1):39–51.
6.
Fournier L, Thomas G, Garnier R, Buisine A, Houze P, Pradier F, et al. 2,3-Dimercaptosuccinic acid treatment of heavy metal poisoning in humans. Medical Toxicology and Adverse Drug Experience. 3(6):499–504.
7.
Friedheim E, Graziano JH, Popovac D, Dragovic D, Kaul B. Treatment of lead poisoning by 2,3-dimercaptosuccinic acid. Lancet. 2(8102):1234–6.
8.
Graziano JH, LoIacono NJ, Meyer P. Dose-response study of oral 2,3-dimercaptosuccinic acid in children with elevated blood lead concentrations. Journal of Pediatrics. 113(4):751–7.
9.
Graziano JR, Siris ES, LoIacono N, Silverberg SJ, Turgeon L. 2,3-Dimercaptosuccinic acid as an antidote for lead intoxication. Clinical Pharmacology and Therapeutics. 37(4):431–8.
10.
Lenz K, Hruby K, Druml W, Eder A, Glaszner A, Kleinberger G, et al. 2,3-Dimercaptosuccinic acid in human arsenic poisoning. Archives of Toxicology. 47(3):241–3.
11.
Mortensen ME, Valenzuela PM. vapor poisoning. Veterinary and Human Toxicology. 4:2,3-.
12.
13.
Centers for Disease Control and Prevention (CDC.

Citation

Copyright

Article metrics

Google scholar: See link

The statements, opinions and data contained in the journal are solely those of the individual authors and contributors and not of the publisher and the editor(s). We stay neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Most read articles

Indexed by