In this research it was examined how fatigue in the working process affected the speed of reaction on a complicated
stimulus, and also on the frequency of inadequate reactions. The investigation was carried out by means method of combine
reaction time (CRT). CRT is the shortest time that passes from the moment when a person is affected by a complicated stimulus until the moment when the person responds to the stimulus, by making adequate and complicated reaction. CRTwas registrated in working population of railroad employees who were divided in two groups:group of locomotive drivers (n= 44) and group of a railroad employees (n=25). In the group of locomotive drivers it was taken into the consideration whether the type of locomotive was electrical or diesel power. In both groups, CRT was registrated in two phases of working process; before and after daily work. Results showed that in both examined groups CRT got significantly extended after the
working process. Duration of CRT was longer before and after working process in the group of electrical power locomotive
drivers compared to diesel power locomotive drivers. Fatigue did not affect significantly on the frequency of incorrect answers

Menopause may influence negatively the cardiovascular system of women, especially that of smokers. The aim of
our study was to compare lipid levels and left ventricular function in postmenopausal women smokers and non-smokers
during 12 months of oral estrogen replacement therapy. The study group included healthy postmenopausal women, 30
smokers and 32 non-smokers. Before and in 6 month intervals the following parameters were followed: total cholesterol,
LDL-, HDL-cholesterol, triglycerides, blood pressure and echocardiographic parameters of systolic and diastolic left
ventricular function. Before therapy non-smokers had higher total and LDL-cholesterol, when compared to smokers. Oral
estrogen replacement therapy significantly decreased levels of total and LDL-cholesterol and increased HDL-cholesterol,
only in non-smokers. No change in lipid levels was observed in smokers. However, women who smoked longer had higher
triglyceride levels after 12 months of oral estrogen replacement therapy. Echocardiography revealed significant improvement of systolic and diastolic left ventricular function in non-smokers, while improvement of only systolic function in
smokers. Our study has shown that 12 months of oral estrogen replacement therapy may not have a protective role on the
cardiovascular system of postmenopausal women smokers

Background: Ultrasonography(US) is a method in diagnosis of hepatobillious tracts. Due to the construction of
modern ultrasound facilities this method presents one of the most important method in this field due to the fact that it is:
uninvasive method, it does not procedure harmful biological effect; it does not demand contrastive means, there are no
counter indications known, and it does not provoke uneasiness to patient. Methods:200 patients were treated ultrasonographically at Surgical Clinic Faculty of Medicine in Pristina. Results: In 119(59,9%) cases calculus in gallbladder was localised ultrasonographically and in 131(65,5%) cases operativelly. Calculus was found in Hartmann's place in 60 (30%) cases ultrasonographycally and in 65(32,5%) cases operativelly. Calculus in d.cysticus was operativelly found in 4 (2,0%) cases and it was not found ultrasonographically. Solitary calculosis was found ultrasonographically in 52 (26,0%) cases and it was confirmed operativelly 47 (23,5%) cases.Multiple calculosis was diagnosed ultarsonographically in(148 74%) cases, and operativelly in 153(76,5%) cases. Anteroposterious radious of gall bladder was found ultrasonographically to be 3 or more then 5 cmm long in 109(54,5%) cases, and operativelly in 111(55,5%) cases. Gallbladder wall size higher than 3 mm was found US in 149(74,5%) cases,and operativelly in 137 (68,5%) cases. Choledocholithiasis was US diagnosed in 29 (53,7%) cases and operativelly in 54 cases. Gallbladder carcinom was US diagnosed in 5(2,5%), and operativelly found in 7 (3,5 %) cases, 6 (3,0%) gallbladder path carcinomes were not US diagnosed. Conclusion:Those results show that ultrasonography is a method of chois in gallbladder disseases treatment accuracy of the method equalls 89,5% on our clinical material.

Hiposmia or anosmia are common cases after infections. The virus of influenza is most common cause of anosmia
and hiposmia. In a cause of hiposmia and anosmia which are the results of influenza it is need to start with regular and actual theraphy, or in other case anosmia or hiposmia are permanent.

The aim of this study was to describe the oral health care system, it's elements (input, process, output and outcome)
and the sociodemographic and behavioral factors relevant to oral health promotion and the oral health care system and to
provide policy markers with information that can be used to improve oral health and the efficiency of the oral health care
system. The modular approach used in the study to guide questionare design, sampling, data collection and analysis is based on Blum's model of the determinants of health status.The study has 3 sources of data: provider surveys, consumer survey and dental epidemiological survey. Logistic regression and data mining was used to establish which of the system's elements has the most influence on oral health outcomes as well as the system outcome. Taking into account sample entropy (.99bit) and value of assessed Bye's error (51.3%) method data mining - (automatic inductive learning) establish use of topical fluorides - fluoride toothpaste as significant factor for the health outcome. Other established factors are variables from input and they are related to dentist and their attitude towards oral health education.

Aim of the study was to determine presence and incidence of perinatal risk in the newborns presenting with the
signs of IUGR or hypotrophy <5% during a 3-year period, and in this way to point the significance of intrauterine diagnostics and special screening during the labor as to reduce the incidence of these factors. Methods: There were 18412 deliveries at the Department of Obstetrics and Gynecology in Novi Sad during the 3-year period out of which number, 560
(3.04%) newborns with IUGR or intrauterine hypertrophy <5%. Results: In the investigated population of 560 newborns
with IUGR or hypertrophy <5%, the following factors of perinatal risk have been recorded: manifest pathological cerebral
signs in 30 cases ( 5.36%), convulsive crises in 6 (1.07%), the crises of apnea and cyanosis in 10 (1.78%), intracranial hemorrhage in 17(3.03%), hyperbilirubinemia in 25 (4.46), hemolytic disease in 6 cases (1.07%), hypoglycemia in 1(0,18%),
disorders of pulmonary ventilation in 26 cases (4.64%) whereas congenital anomalies were evidented in 19 ( 3.39%)
newborn infants. Exanguination transfusion was administered in 4 (0.71%) and transfusion in 9 (1.61%) newborns with
IUGR, i.e. intrauterine hypotrophy <5. Conclusion: The results of investigation show the significant presence of perinatal
risk factors in the population of the newborns with IUGR leading to the increased morbidity in later periods of life. 

Despite of Aspirin use in acute virus infection and reduce of incidence in many parts of the world, the Reye's syndrome is also actual in our country. Reye's syndrome was described for the first time in 1963. It's a non-inflammatory encephalopathy and lipid infiltration of liver and other organs. Etiology is unknown. Some viruses, some chemical compounds,
Aspirin and genetically abnormal answer have the role. The damage of mitochondria appears. Organism is in hard catabolism. The biochemical parameters in serum and liquor were followed at 26 children cured in treated in Pediatrics Clinic in Priština in the period from 1991-1998. The extreme hypoglycemia (<2.2 mmol/L) was in 46,1%, medium hypoglycemia
(2,3-3-,3 mmol/L) in 7,7%. Three times high transaminases appeared in 46% of children. The level of chaemostasis was reduced in 11,5% of children. Half of the total number children had the higher values of urea and creatinine. Hyperproteinorachia in liquor was 27% and hypoglycorachia was 19,3%. Metabolic acidosis was present in 61,5%. Half of the children had convulsions and pneumonia. Enterocolitis, acute renal insufficiency, anemy and urinary infection were also present.

Spinal anesthesia is one of type of central block anesthesia. It is an anesthesia of choice for surgical procedure open prostatectomy. According to our experience this type of anaesthesia is more safe than the other type of central block or regional anaesthesia in a high risk patient for surgical procedure prostatectomy. In a 10 years period we have given in a 242
patients spinal anaesthesia for prostatectomy. From the complication after giving of spinal anaesthesia according to our data
were: 1. post-spinal head-ake (3-5 days) - 5 patients; 2. post-spinal head-ake (vp to 3 days) - 6 patients; 3. paraparesis (to
36 h) - 1 patients; 4. local pain on the back - 1 patients; 5. CVI - 1 patients; 6. MI - 1 patients; 7. mortality rate - 0. We can
conclude that spinal anaesthesia is one of anaesthesia of choice for prostatectomy.

In this work the authors have treated patient with a wide range of skin symptomes and a various clinical sings and
manifestations of this serious bullous skin disease. The complications such as secondary bacterial infections on eroded
areas and swallow difficulties, because mucous membrane of oral cavity was affected, have supplemantary disabled quick
and efficient therapy. Therapeutical problems were presented as weakness, exhaustion, obstruction syndrome and asthmatic
constitution of a patient. The high doses of corticosteroids could provoke a hypertension, but still, with gradually reduced
doses of corticosteroids, supported by local therapy with antibiotics and corticosteroids, we achieved rehabilitation and
healing of our patient

Vitiligo manifests with hypopigmentated and depigmentated plates on the skin and mucous membranes. Etiopathogenic mechanism of disease appearing is not completely explained, though there are theories explaning the appearance of the disease. Precipitant factors, especially psyhotic stress, are very important for the appearance of the disease. The
patients usually come because of cosmetics defects, because vitiligo areas appear mostly on uncovered parts of a body. We
are presenting a girl, with the first sings of the disease appeared when she was seven, located symetrically periorbitally and
in capilicium followed by polyosis. The beginning of the disease might be connected with a psychotic stress.