Rheumatoid arthritis is a chronic multisistemic disease of an unknown cause characterised by persistens inflammatory synovitis which results in destruction cartilage and bone erosions. RA is a systemic disease with various out of joint manifestations of different clinical importance, among which rheumatoid knots, rheumatoid vasculitis, pleuropulmon...

By M. Mirković, V. Jakšiċ, D. Vukša, D. Stamenković, S. Bulajić, Z. Petković, S. Elek

Endometrial hyperplasia appears like a result of continues, not mortified stimulation of endometrial by estrogenically hormones. Endometrial becomes nub which histological mirrors in endometrial gland multiplication, in smaller amount even endometrial strom. Endometrial polyp represents focal overmuch growth of gland stromas endometrial and its con...

By D. Vukićević, N. Mitić, M. Mijović, B. Đerković

This article aims to promulgate the use of Microsoft Excel, one of the predominant spreadsheet applications, in the calculation of approximate functions by the method of spline polynomial interpolation. Cubic spline functions have demonstrated a remarkable suitability for the analysis of pharmacokinetic data of drugs with non-linear kinetic behavio...

By R. Mitić, J. Damjanović

In diabetics fungal skin infections are reported to be related to greatly disturbed metabolism. In order to get better insight into the association between diabetes mellitus and fungal skin infections, we started our study with the aim to assess the effect of metabolic regulation on the incidence of fungal skin infections is diabetics. The obtained...

By Z. Sojević-Timotijević, T. Novaković, G. Trajković, T. Radević, M. Relić, D. Staletović

Arthrosis (A) are the degenerative-dystrophic disease of the peripheral ankles. Etiology is unknown. The genetic factor and external factors, mostly of a mechanical nature are the crucial ones, however, in the literature more emphasis is put on the infection factor and participation of immunity in the etiology of the patogenesis A. We have treated ...

By S. Minić, S. Ivković

Acute instable atherosclerotic plate in the basis of the pathophysiology of the acute coronary syndrome and it is divided on two big groups: a) acute coronary syndrome without ST elevation (NONSTEMI) and b) myocardial infarction with ST elevation (STEMI). Clopidogrel belongs to the group of antiaggregation drugs which inhibit ADP receptors and on t...

By S. Sovtić, R. Stolić, Z. Marčetić, V. Perić, S. Lazić, M. Šipić

Diabetic retinopathy is the microangiopathy which procedures pre capillary arterioles, capillaries and post capillary venules. The length of disease and poor metabolic control, have the biggest impact on development and progression of DR. By the prospective study in Gracanica Health House, for the period time of six months, there were matched 50 pa...

By I. Kostić-Inić, Lj. Božanić, T. Novaković, N. Đokić, A. Đokić, S. Trajković, Z. Nedeljković, S. Samardžić

Epidemiological characteristics of acute stroke certify the great importance of such disease, which takes the measures of a mass incontagious illness, because it represents one of leading causes of death and invalidity in the world. Contemporary knowledge about the complexity of cerebral infarct has been significantly increased thanks to new imagin...

By S. Filipović, V. Mitrović, N. Petrović, D. Ljuši

The two most common types of skin cancer are basal cell and squamous cell carcinoma, well known as nonmelanoma skin cancers. These cancers are the most common malignant tumors in white population and its incidence is increasingdramatically. Information about the time of occurrence and cancer growth rate is a significant segment in establishing the ...

By G. Videnović, D. Vukićević, I. Tripković

Even 1000 years BC the famous Persian physician Aviccena describet the first time gangrene diabetes mellitus as a complication. Basic pathohistological substrate vascular complication is atherosclerotic plaqueand therefore is an adequate treatment opf patients with vascular disease is conditioned by timely and precise diagnosis.The introduction of ...

By M. Smuljić, A. Jovanović