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Volume 53, Issue 4, 2025

Online ISSN: 2560-3310

ISSN: 0350-8773

Volume 53 , Issue 4, (2025)

Published: 30.06.2025.

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15.01.2014.

Review scientific paper

Ogromna ovarijalna cista u adolescentnoj dobi

U literaturi se razlikuju podaci u smislu koje su najčešće ciste jajnika u ovoj starosnoj dobi. U našem slučaju pacijentkinja uzrasta 14 godina je operisana zbog postojanja velike ciste desnog jajnika, veličine oko 25 cm, koja se torkvirala što je dalo sliku akutnog abdomena i iziskivalo hitan operativni zahvat. Prilikom sprovedene dijagnostike od najveće pomoći su bili anamneza, u kojoj navodi akutno nastali bol pri fizičkoj aktivnosti, ultrazvučni pregled (UZ) koji je nedvosmisleno ukazao na postojanje tumora, kao i CT (kompjuterizovana tomografija).Tumor markeri su bili granični (u odnosu na referentne vrijednosti).Urađena je laparotomija sa adneksektomijom. Patohistološki nalaz (PH) govori da se radilo o mucinoznom cistadenomu. Evaluacija u smislu kliničke obrade i tretman ovarijalnih cisti su među najčešćim razlozima zbog kojih adolescenti taraže pomoć ginekologa.

A. Grdinić, G. Vukčević, A. Bajmak, A. Radović, G. Marijanović, S. Raičević

15.01.2014.

Original paper

Antropometrijske mere kod obolelih od akutnog infarkta miokarda sa i bez metaboličkog sindroma

Insulinska rezistencija je stanje udruženo sa genetskom predispozicijom, sedantarnim načinom života i starenjem. Ono je izazvano i podstaknuto gojaznošću. Metabolički sindrom (MS) pak, predstavlja koincidentno postojanje više metaboličkih poremećaja u čijoj se osnovi nalazi insulinska rezistencija. Cilj ovog rada je bio da se utvrde antropometrijske mere kod obolelih od akutnog infarkta miokarda (AIM) sa i bez metaboličkog sindroma. Prospektivnom studijom obuhvaćeno je 77 bolesnika oba pola koji su lečeni zbog AIM u koronarnoj jedinici Interne klinike-Laplje selo KBC-a Priština sa sedištem u Gračanici. Bolesnici sa reinfarktom miokarda nisu uključivani u istraživanje. Od ukupno 77 ispitanika sa AIM 44 ispitanika je imalo MS ili 57,1% dok je 33 ispitanika bilo bez MS, ili 42.9%. Naše istraživanje je pokazalo sledeće: učestalost MS kod ispitanika lečenih zbog AIM je bila 57,1%; u odnosu na polnu zastupljenost nije nađena bitna razlika između ispitanika sa AIM sa i bez MS ; u grupi ispitanika sa AIM i MS muškarci su bili zastupljeniji (63,6%) u odnosu na žene; nije nađena bitna razlika između poređenih grupa ispitanika u odnosu na starosnu zastupljenost ; poređenjem telesne visine i težine između ispitanika sa AIM sa i bez MS nije nađena značajna razlika ; dobijena je bitna razlika između poređenih grupa ispitanika u odnosu na indeks telesne mase-BMI. Prosečna vrednost BMI kod ispitanika sa AIM i MS je bila 29,34 kg/m2.

G. Antić, M. Mrdak, M. Antić, S. Marković, Z. Marčetić

01.01.2011.

Original scientific paper

ANTIOXIDANT ROLE OF ASCORBIC ACID IN OXIDATIVE STRESS INDUCED BY STERENOUS EXERCISE

Strenuous exercises greatly increase oxygen consumption in the whole body, especially in skeletal muscles. Large part of oxygen consumption is reduced to H2O and ATP, but smaller part (2-5%) results in an increased leakage of electrons from the mitochondrial respiratory chain, forming various reactive oxygen species-ROS (02, H2O,iOH). These free ra- dicals are capable of triggering a chain of damaging biochemical and physiological reactions (oxidative stress, lipid peroxi- dation), as a base for skeletal muscles damage after exercise. MDA (malondialdehyde) is a marker of exercise induced lipid peroxidation process. L-ascorbic acid is a major aqueous-phase antioxidant. To estimate antioxidant role of ascorbic acid we use rate between dehydroascorbate and ascorbate. In this paper those markers of lipid peroxidation (MDA, MDA ind, % ind MDA), and ascorbic acid status (ascorbic acid Asc, ascorbat A, dehidroascorbat DHA, DHA/A) were determinated in 30 stu- dents, in rest and after treadmill running protocol (Bruce Treadmill Protocol). It was found that after the treadmill test, plas- ma MDA level had increased from 3,04 to 4,39 M/L (p<0,0001) and % ind MDA decreased significantly from 35% to 24,7% (p=0,0003). Plasma ascorbic acid was also found to be higher after the treadmill test comparing to rest level (from 55,4 to 67,6 μM/L). DHA/A level in rest was 1,62 and after treadmill test it increased to 2,05 (p=0,0014). These results suggests that strenuous exercise increased process of lipid peroxidation (MDA †, % ind MDA), but in the same time incre- ased ascorbic acid level in plasma and DHA/A rate indicates stronger activation of nonenzymatic antioxidant defense system.

Lj. Popovic, R. N. Mitic, I. Radic, D. Miric, B. Krdzic

01.01.2011.

Original scientific paper

THE CEPHALOMETRICS ANALYSIS OF MORPHOLOGICAL CHARACTERISTICS CLASS III MALOCCLUSION

Class III malocclusion are complex anomalies of the skeletal and dental systems. The aim of this study is that the sample of 30 untreated orthodontic patients, aged 18-30 years, rendgencephalometrics analysis closer to determine the mor- phological characteristics of this malocclusion. In patients previously clinically diagnosed class III. For this analysis, were used in a number of cephalometrics points on the basis of which the measured angles and planes. The results were compared with the patients with class I malocclusion and they point to the following morphological characteristics of class III maloc- clusion: a smaller cranial base, normognathic and normal size maxilla, prognathic mandible and chin, the greater the total mandibular length, open gonial angle and a larger anterior and lower posterior facial height.
Key words: malocclusion; morphology; cephalometrics

J. Pavlovic, S. Simic, V. Vukicevic, A. Vujacic

01.01.2011.

Original scientific paper

CEPHALOSPORINS AND NEPHROTOXICITY

Cephalosporins are bactericidal antibiotics that are active against a wide variety of Gram(+) and Gram(-) aerobic bacteria, along with a few anaerobic species. Adverse effects of cephalosporins are uncommon and reversible. Cefalotin and cefaloridine exhibit a nephrotoxic effect and might cause renal tubule necrosis. No data about the nephrotoxicity of cefotaxime and ceftriaxone has been presented in literature so far. When cephalosporins are applied via intramuscular injection a local reaction is possible, whereas with IV administration thrombophlebitis develops in about 5% of all cases. Hypersensitivity reactions, as well as some hematological disorders (thrombocytosis, leukopenia, neutropenia) might also occur. Cephalosporins were found to sometimes cause an augmentation of transaminase (AST, ALT), alkaline phosphatase, and, less frequently, bilirubin levels, too. The goal of this study was to evaluate the creatinine values in the serum of patients hospitalised in Kosovska Mitrovica Health Centre. The values were determined before, within and after 7 days of cephalosporin administration (cefotaxime 2x1000mg IM; ceftriaxone 2x1000mg IV). Data concerning certain hematological and biochemical variables will be presented as well. Creatinine levels were measured by the Jaffe reaction method. Both cefotaxime and ceftriaxone yielded a statistically significant increase of the serum creatinine values. As these cephalosporins do not show a nephrotoxic effect, the increase can be explained by the interference of sodium picramate, a byproduct of the Jaffe reaction which is produced regardless of whether the process is manual or automated.

M. Stanić, R. Mitić, S. Pajović, V. Adžić, K. Bulatović

01.01.2011.

Original scientific paper

THE IDENTIFICATION OF MORPHOLOGICAL CHARACTERISTICS RELATED WITH HORIZONTAL BODY AXES OF HANDBALL AND FOOTBALL PLAYERS

Many research projects that deal with the transformations of morphological characteristics have pointed out their extensive complexity, considering the fact that they are the result of genetic factors (endogenic influence) as well as factors pertaining to the environment (exogenic factors), where it is necessary to point out that the influence of genetic factors is not the same for all of the latent morphological dimensions. Òhe different positions of the biacromial and bicristal range in the latent and taxonomic structure of morphological characteristics that have contributed to the actualization of the problem of the relation between the first and second horizontal axis of the body, as well as their relations to the other components of morphological status. Taking that viewpoint, we defined the aim of this research to identify those morphological characteristics which are to the greatest extent related to the development of the horizontal axes. Using a sample of 130 athletes, handball players (N=70) and soccer players (N=60), aged 16 to 27, all of whom play in national leagues, and using a system of 21 anthropometric variables, we analyzed the relations between the first and second horizontal axis of the body, and their connection to the development of the remaining morphological characteristics. The first horizontal axis was defined as the biacromial range and the other as the bicristal range, while the remaining morphological characteristics were defined as the 19 standard measurements of longitudinal and transversal dimensionality, volume and body mass, and subcutaneous fatty tissue. When calculating the connection between the first and second horizontal axis and the remaining variables of the morphological system, we used the Pearson correlation coefficient. In addition, we calculated the dimorphism index for the biacromial and bicristal range as the point of the biserial correlation between the peripheral types of sport and every horizontal axis. It has been determined that in the case of handball players, it is possible to talk of biacromial and bicristal variants of an ectomesomorphic body type, while in the case of soccer players, of a biacromial variant of an ectomorphic type and a bicristal variant of an endomesomorphic body type. Both in the case of the biacromial and bicristal range, the dimorphism is pronounced among athletes who belong to different populations. 

V. Stanković, M. Popović

01.01.2011.

Original scientific paper

ASSOCIATED OCULAR FINDINGS IN PATIENTS WITH OCULAR CONTUSION WITH HYPHAEMA

Ocular contusion followed by hyphema is very common ophthalmologic problem. Aim: to determinate basic epidemiologic characteristics, comorbidity of other ocular findings, as well as complications associated with different grade of hyphema. Method: 55 patients with hyphema and ocular contusion were examinated. Results. Male had hyphema almost four times more often then women (80%:20&); workers (34.5%), afterward pensioners (20%) and pupils (18.2%) were the most often injured. The most frequent causes were the wood (43.6%), stone (10.9%) and vegetable foreign body (9.1%), The first grade of hyphema was demonstrated at 30 patients (54.5%), the second at 16 (29.1%), the third at 6 (10.9%) and the fourth at 3 (5.5%). The most frequent associated ocular findings regarding to segments were the following : haematoma palpebrarum, subconjunctival hemorrhage, erosio corneae and haemophthalmus. Secondary glaucoma was the most common ocular complication and it was finding at one patient with the first stage of hyphema but at all patients with the fourth grade of hyphema. Conclusion: grade of hyphema is directly proportional with a grade of ocular complications and frequency of associated ocular findings.

D. Vukša, D. Stamenković, V. Jakšiċ, M. Mirković, O. Đokić, Z. Dolićanin

01.01.2011.

Professional reviews

GOITERS NODES THYROID GLAND AS A RESULT OF MODIFIED APOPTOSIS AND METHODS FOR DETERMINING

Hyperplasia in goiter may be associated with altered apoptosis thyrocytes. There are numerous techniques for the detection and quantification of apoptosis. Some of them were light microscopy, electron microscopy, flow cytometry, studying the activities of caspase, DNA fragmentation and so on. In patients with multinodular endemic goiter after six months of iodine load, number of apoptotic thyrocytes increased by ten times, Bcl-2 is missing and Bax appeared in thyrocytes. Excess iodine in molecular form causes apoptosis in thyrocytes creating free radicals, mitochondrial damage and release of cytochrome c. Research shows that the level of sFas in the serum of patients with multinodular goiter increased compared to normal controls, it can still point to the reduced expression of Fas protein on the surface of cells that then leads to increased thyroid cell proliferation. Further study of apoptosis in goiter combined morphological and biochemical methods are important for better diagnosis and treatment of diseases.

J. Aritonović Pribaković, Lj. Marković

01.01.2011.

Case Reports

HYPERKALEMIA - A CASE REPORT

In clinical hyperkalemia, correlation between plasma K and the ECG is less reliable. A tall, peaked, symmetrical T wave with a narrow base, the so-called "tented" T wave is the earlinest ECG abnormality, usually best seen in leads II, III, V2, V3, and V4. The tented appearance and the narrow base are probably more characteristic of hyperkalemia than is the amplitude of the T wave. A decrease in amplitude of the R wave, appearance of a prominent S wave, widening of the QRS complex, depression of the ST segment evolve as plasma K approaches 8-9m Eq/liter. With hyperkaliemia, depression of intraventricular conduction is characteristically diffuse and results in prolongation of both the initial and terminal parts of the QRS complex. The resulting pattern may resemble RBBB, LBBB, left anterior or posterior divisional block, or a combination of the four.

S. Lazić, D. Čelić, Z. Marčetić, S. Sovtić, R. Stolić, V. Perić, M. Šipić, B. Krdžić

01.01.2011.

Case Reports

CONSERVATIVE CARE OF ENDODONTIC TREATED TEETH WITH GREAT DAMAGE OF CROWN- REVIEW OF FOUR PRACTIC CASE

There are different stick types and shapes, different root canal preparation techniques, as well as different materials for stick cementing and making annexes around posts. The use of fiber-reinforced resin posts to restore endodontically treated teeth has gained popularity due to its mechanical and esthetic characteristics as well as properties of modern adhesive systems. The aim of this article was to show a clinical technique to reconstruct endodontically treated teeth with great loss of tooth structure using direct fiber-reinforced post systems and direct composite restorations. After the preparation of the root canal and cementation of a FRR post, particular attention was paid to the incremental and curing techniques adopted to reconstruct coronal part of the tooth. It is possible to place of fiber-reinforced resin posts. 

D. Živković, V. Matvijenko, M. Živković, D. Perić, R. Jovanović, M. Miladinović, Z. Milosavljević, M. Staletović, R. Radosavljević, N. Gligorijević

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