Biliary pathology represents today one of the most common indication for surgery in abdominalnj surgery. Calculosis gallbladder is a serious pathological condition, that their frequency, severity and possible complications constitute a significant percentage of medical emergencies. Septic complications are the most important factor of morbidity and mortality in biliary surgery. In relation to the gender structure of M: F=160: 519 1 3.2 23.6%: 76.4% is female domination. The highest incidence of biliary diseases in this interval is 91 (13.4%) in 2006, and 75 (11.0%) of 2010 average incidence of 52 patients per year. The lowest incidence was 2002 g 6 (0.9%) patients. The youngest patient was females aged 12 years. The oldest patient who underwent surgery were female, with a 82 yr. The range is 82-12=70g. The average age of the patients was 51 years, with dominant females 76.4%. Cholecystitis chronice is present in 423 (62.3%), cholecystitis acuta 251 (37%). Cholelythiasa 666 98%. Acalculosa 13 (1.91%). Calculosis gallbladder was present in 666 (98.1%) cases. OP: Solitary holelithiasis, 149 (22.4%), multiple holelithiasis 517 (77.6%). The absence of cholelithiasis in biliary diseases was verified in 13 (1.91%) patients. Holecistit empyema was verified in 8 (1.18%) cases. The structure of the surgical findings shows that gallbladder represents the dominant place of infectious processes in the acute pathology of extrahepatic bile ducts. 436 (64.2%). Hydrops 47 (10.8%). Empyema 102 (23.4%). Acute complications related to the spread of infection from the gallbladder put the main biliary tree and free abdominal cavity were registered in 2 (0.46%). Abscessus subhepatis 11 (2.52%). Choledocholythiasis 6 (1.38%). Cholangitis ac 17 (3.9%). Neo vesicae felleae 7 (1.03%). From that polypus vesicae felleae 2 (0.4%), ca vesicae felleae 4 (0.59%). There hepatocholedoci 1 (1.15%). Meta and hepato 4 (0.59%). M: F = 2: second Icterus 8 (1.18%). The ratio of M: F = 7: 1. Incidenca baktibilije analyzed in the entire series was 57%. Microbiological analysis of samples identified teen bacterial species.