Chronic obstructive pulmonary disease (COPD) is a disease with periods of remission and exacerbation and consequential defect of the pulmonary function. It is estimated that around 3 million people die from it annually and predicted that until 2030 the number of deaths will be up to 6 million per year. According to the reports of the World Health Organization and Global initiative for chronic obstructive lung disease (GOLD) it is predicted that COPD in the next decade will be the third leading cause of death in the world.[ 1, 2 ] It is characterized by limited air flow in the breathing pathways which is not completely reversible to therapy. Since there are systemic inflammations at COPD, the mechanisms of the processes have consequences outside the lungs also. Comorbidities are frequent at patients with the Chronic obstructive lung disease and they affect the disease prognosis substantially. The most common comorbidities are cardiovascular diseases, metabolic syndrome, diabetes, anemia, osteoporosis, anxiety and depression, pulmonary embolism.

Introduction: Hernia is a defect of the continuity of the normal musculoaponeurotic and fascicular abdominal wall, which allows the release of any tissue, except those that normally pass through the apertures on the abdominal wall. Aim: The aim of the paper is to show the frequency of pathological changes in the inguinal region, their timely diagnosis and treatment, in order to avoid the severe consequences of their complications. Material and methods: For this study two-year material of the Surgical Clinical Hospital Clinical Hospital Priština in Gracanica was used, where we analyzed 102 patients who were operated in this center due to pathological changes in the inguinal region. Results: Male males are represented by 91 (89.22%), and female sex with 11 (10.78%) cases. Hernia was recorded in 86 (84.31%) and testicular retention in 16 (15.69%) patients. Femoral hernia in children is extremely rare and occurs in about 0.2% of all hernias of childhood. The femoral hernias on the left with faded and gangrenous left adnex were found in a baby only three months old, where adnectomy was done. Primary hernias was 84 (97.63%) of the patients, while we recorded recurrent hernias in two (2.33%) patients. With one child, we did a recurrent retention of testicles, which was done for a year in another institution. Postoperative complications were reported in one (0.98%) patients, where there was an infection of the wound. Conclusion: In modern surgical practice, it tends to diagnose the hernia at an early stage of development, which facilitates intervention and provides a better postoperative outcome. Incarceration represents a serious complication of all hernias, so timely and accurate diagnosis is needed to take adequate surgical intervention.

INTRODUCTION: Urinary tract infections are one of the most common infections in young children. Febrile conditions in young children, without specific clinical signs and symptoms are often the result of ITU. Usually later diagnosed and treated. The most common cause of ITU is Escherichia coli. The main problem in the treatment of ITU is increasing resistance to antibiotics. AIM: To point out all the frequent resistance to antibiotics and to compare the frequency of the experimental periods. MATERIAL AND METHODS: We performed a retrospective study in the period of 2010-2015. Urine samples for microbiological examination were taken before switching on antibiotics. Statistical analysis was performed in SPSS software. RESULTS: In our study found 183 patients with a diagnosis of ITU. Somewhat higher percentage were present, patients were female. The highest resistance to ampicillin was found in our results in the time period is 5 years, found a drop resistance Amoxicilin and Amoksiklav. DISCUSSION: Our results showed a strong similarity with the works on the same theme, which is Escherichia coli, the most common cause of ITU in young children. ITU are represented within the female population. CONCLUSION: It is important to continuously monitor the representation of urinary tract infections as well as their sensitivity to antimicrobial drugs, because of the increasing presence of the bacterial resistance to existing antibiotics.

Introduction: A self-assessment health condition provides a general approach to creating a picture of the health status of the population. Aim: The aim of the paper is to show the connection between different categories of self-assessed health with socio-demographic characteristics, risk factors and with the presence of one or more chronic non-communicable disease of adults in Serbian communities in Kosovo and Metohia. Method: The research was carried out as a cross section study. As an instrument for data collection, the questionnaire was applied in the 2013 Survey of the Health of the Population of Serbia (excluding Kosovo and Metohija), which is in line with the European Health Research Questionnaire. For the purposes of our research, the following variables were used; gender, age, education, working status, marital status, the presence of chronic non-communicable diseases, smoking, alcohol use and physical activity. Results: A total of 1067 respondents (51.3% of women) responded, with an average age of 42.2 (± 16.0) years. Most respondents in the survey found that they feel very good or good, a quarter of the middle (not bad or good), while their condition was poor or very poor assessed by just under 5% of respondents. Among the respondents who rated their health condition as poor or very poor, there were significantly more female respondents, middle age and 65 years of age. Also, people with primary and secondary education, economically inactive, and who are inclined to the sedentary way of life, have a poor picture of their health. The frequency of people who assess their health status as bad or very bad is the highest among respondents with two or more chronic diseases. Conclusion: Different categories of self-assessment health show a tendency to connect with different individual characteristics of adult respondents. Our results can help in creating a strategy of action and building preventive programs in a defined area.

Teledentistry is an applied discipline of telemedicine in dentistry. In recent years, this area has been in the focus of interest of researchers. Their studies predominantly deal with the reliability of the methods of teledentistry and their feasibility in various conditions and situations. The studies based on photography and communication of visual information via smart mobile phones have been especially popular. This paper represents a review of the studies about teledentistry published in the last several of years, discuss them and puts forward the recommendations for future research.

Introduction: During the course and development of diverse cardiological diseases different central nervous system complications may develop. These are most frequently related to the nature of the cardiovascular entity itself. Aim: To evaluate the association between atherogenesis factors and border zones strokes within the cerebral medial artery vascularization territories. Methods: In total 30 patients were enrolled in the study. Stroke diagnosis was based according to clinical and neurological examination and brain CT findings. The study analyzed risk factors correspondingly to World Health Organization criteria. Results: In majority of patients (18; 60%) arterial hypertension was diagnosed. Additionally, following condition and risk factors were identified: cardiological diseases (17; 23.3%), cigarette smoking (13, 43.3%), hypercholeterolaemia (9; 30%) and diabetes (7; 23.3%). In the group with cardiological diseases most frequent was myocardial infarction (9; 56.2%), AV block II and III (5, 29.4%), atrial fibrillation with slow ventricular response (3; 17.6%). Conclusion: Results of the study point to conclusion that myocardial infarction, AV block II and III, atrial fibrillation with slow ventricular response, iatrogenic hypertension and traditional risk factors for atherogenesis significantly influences presentation of the border zone strokes within the cerebral medial artery vascularization territories.

It is well known that there is a relationship between the zinc and diabetes, and its antioxidant potential. Based on that, the aim of this paper is to investigate the effects of different doses of zinc (9,2 and 18,4 mg / day) in combination with metformin and glibenclamide, to the total antioxidant status (TAS) and the activity of the enzyme superoxide dismutase (SOD) in experimentally-induced diabetic rabbits. The study was conducted on 24 New Zealand rabbits of both sexes, body weight 2,5 to 3,2 kg. In rabbits, experimental diabetes was induced i.v. injection of alloxan (80 mg / kg body weight). Three weeks after causing diabetes, the animals were divided into two groups: first group was treated oral with metformin, an appropriate dose (120 mg / kg body weight), while the second group of rabbits was treated with a suitable dose of glibenclamide (0,6 mg / kg BW). After the washout period (10 t1/2), the rabbits were treated with metformin and a first dose of zinc (9,2 mg) combination, i.e. glibenclamide and zinc (9,2 mg). After another washout period (10 t1/2) the rabbits were treated with metformin and a second dose of zinc (18,4 mg) combination, i.e. of glibenclamide and zinc (18,4 mg). Blood samples were taken in a specified time interval. The TAS value was significantly increased after administration of metformin, single and in combination with zinc, in doses of 9,2 and 18,4 mg, with respect to the value recorded before their application (p <0.05). Also, it is noted a significantly increased SOD activity after administration of metformin (i.e., glibenclamide), and zinc in combination, in a dose of 18,4 mg (p <0.05). This indicates that zinc and metformin have a significant positive effects on the parameters of antioxidative status, but with glibenclamide this effect did not occur.

Topiramate is a newer drug with a strong antiepileptic potential, but also with adverse effects, especially on cognitive functions. This review deals with the study covering the impact of topiramate on cognition in patients with epilepsy. The most common side effects are included somnolence, psychomotor slowing, difficulty in memory, concentration and attention disorder and problems with speaking. Most studies have shown that a high initial dose, rapid titration and application in polytherapy increase the risk of cognitive impairment after-introduction of topiramate. In addition, depression and early onset of the disease can also contribute to cognitive adverse effects, even at low doses of the drug. Although topiramate indisputably linked to the risk of interference cognitive impairments, some studies suggest their reversibility. This, together with high efficiency antiepileptic obliges researchers to continue searching for the risk factors and mechanisms of cognitive side effects in order to define the profile of patients who would be of maximum benefit of the drug in controlling seizures with absent or acceptable side effects.

Arthritis following dyzentery or urethritis was mentioned before our era and later by many others. In 1818 Benjamin Brodie described 5 patients with typical „ Reiters disease”: urethritis, conjunctivitis, arthritis. Many diagnostic criteria for Reiters disease / reactive arthritis have been proposed for practical purpose the most acceeptable is the folowing one: posturethritic or postenterocolitic arthritis is Reiters disease / reactive arthritis. The findings of Chlamydiy from the synovia or in the synovial fluid of itients with RD suggest that arthritis may be of infective but not of reactive origin.

Salmonellosis are food-borne toxinfections flowing with the clinical picture of acute enterocolitis, and are caused by non-typhoid salmonella (Salmonella food poisoners). The main objective of the study was to identify the most important epidemiological characteristics of salmonellosis in Serbian areas of Kosovo and Metohija We used the data or reporting of infectious diseases, reports on infectious diseases (seven-day, month, year) of the Public Health Pristina in Kosovska Mitrovica. In our research we used epidemiological Studies of cross-section (cross-sectional) Between 2003-2015.god. Kosovo and Metohija (Serbian middle) registered 250 cases of salmonella. The average incidence in the reporting period was 12.35 / 10,0000. Analysis of age distribution revealed that the most common incidence in people aged 20-29 years, and the rarest people ages 15-19 godina.salmoneloze occur throughout the year showing seasonal variations. The trend in the incidence of salmonellosis is decreasing in the territory of Kosovo and Metohija Based on the results of our study we can conclude that a significant salmonellosis both public health and animal health but also economic problem .Epidemiological situation with regard to salmonella requires intense activity in the field of food safety not only medical services, but also veterinarians and veterinary and sanitary inspection.