Introduction: Clinical features of the ischemic neurovascular syndromes is constant and dependable from vascular territory of the affected blood vessel. Best examples are sensory and motor hemisyndromes and vision disturbances. Aim: To define motor, sensory and visual disturbances’ in patients with ischemic stroke in the border zone of the middle cerebral artery. Material and methods: Border zone ischemic stroke diagnosis was based on clinical and neurological examination and confirmed with brain computerized tomography. Estimation of the symptoms was obtained by history, and degree of functional (neurological) deficit was estimated based on NIH-NINDS scale. Results: In total 30 patients were included in the study, 12 (40%) were females 47-79 years of age (±62.3 years) and 18 (60%) males 43-79 years of age (± 58.7 years). Neurological features were clearly different based on the side of the infarct. In the group with (ACA+ACM) + (ACM+ACM) infarct localization hemiparesis is significantly more frequent. In the group with ACM+ACP infarct localization homonymous hemianopia is significantly more frequent. Initial symptom of the reversible loss of consciousness in duration of several minutes was observed in 14 (46.6%) patients. Focal seizures (clonic seizures of the face, arm and leg) were detected in 4 (13.3%) patients (all with infarcts in the anterior border zone ACA-ACM). Headache was rare manifestation seen in 5 (16.6%) patients with 4 having posterior border zone infarcts. Conclusion: Supratentorial border zone infarcts have high specificity in clinical manifestations. The implicates therapeutical approaches which are prone to specific procedures.

Introduction: Dental related oral mucosal lesions are most often complications of wearing removable dentures. Painful lesions treatment beside removing ethiologyical factor is symptomatic therapy. Recent investigations of ozone have reported that ozone can induce the wound healing. Case raport: A patient with three ulcerative lesions subsequently developed as a result of wearing implant retained overdenture were included in the study. Each lesion recived conventional care whereas tested lesion recived topical gaseous ozone therapy additionaly. Ozone was applied directly on the musocal lessions for three times in 1 week (baseline-1.day-3.day). The basic result were changes in greatest dimension of every lesion from first treatment and at days 1 and 3. Conclusion: The current case report showed positive effect of gaseous ozone on accelerating the process of healing and pain reduction but future clinical studies are needed to confirm these findings.

Introduction: patients undergoing hemodialysis has numerous ophthalmological complications. Aim: To explore if the dry eye disease incidence, in patients undergoing hemodialysis, exists and if its frequency is greater compared to the healthy subjects. Methods: A total of 126 patients undergoing hemodialysis as well as 23 healthy subjects underwent complete ophthalmological examinations. The dry eye disease tests were performed in the patients undergoing hemodialysis: Schirmer test, Tears Break Up Time (TBUT) test and “Red eye syndrome”. Results: Comparing findings of dry eye disease parameters in patients undergoing hemodialysis vs. healthy subjects findings were the following: Schirmer’s test results 52,78% vs. 36,36%, (χ2 = 4,02, p=0,0448, p<0,05) and “Red eye syndrome” 38,10% vs 19,05% ( χ2 = 5,69, p=0,0170, p<0,05), while the TBUT test has shown pathological results in 38.89% of undergoing hemodialysis patients. Conclusions: Dry eye disease is significantly more frequent in patients undergoing hemodialysis than in healthy subjects.

Introduction: Radiological diagnostics is the dominant diagnostic discipline in medicine. The level of technical equipment of radiological departments directly affects many aspects of importance for the diagnosis of a large number of pathological conditions and, therefore, the progress in the treatment of patients. Aim: The research analyzes the existing situation in radiological cabinets on the territory of AP Kosovo and Metohija. Particularly important elements will be analyzed for the functioning of the radiology service. An analysis of the obtained results gives recommendations in order to improve radiological diagnostics. Metods: A survey was conducted to obtain relevant data. A questionnaire consisting of segments containing basic elements for determining patients' accessibility criteria, equipping the cabinet with equipment and employing professional staff was designed. This formulated questionnaire was sent to radiological departments in health institutions on the territory of AP of Kosovo and Metohija, which are part of the Ministry of Health of the Republic of Serbia. Results: The highest percentage of radiological equipment is represented in KBC Kos. Mitrovica and KBC Pristina-Gračanica, a total of 54%. The percentage of medical staff is at KBC Kos Mitrovica radiologist 50%, work technician 36%. This is followed by KBC Prishtina-Gračanica with 25% radiologists and 27% of radiological therapists. Conclusion: The basics of radiological diagnosis are conventional x-ray techniques. Tertiary health care does not adequately possess radiological high-tech modes of computerized tomography and magnetic resonance. Staff training is required in order to re-establish existing knowledge and skills development that are followed by the continuous professional development of technology applied in radiological practice.

Introduction: The intracranial part of the optic nerve is perfused by the upper hypophyseal and ophthalmic arteries. Standard anatomical textbooks have not dealt with the vasculature of this clinicaly important part of the central nervous system. Objective: To study morphological characteristics of perioptical arterial vascularization of the intracranial part of optic nerve. Material and methods: The study was conducted on 18 whole brains of both sexes (11 male and 7 female), from the age of 51-78 years, with no signs of changes in the structures of the central nervous system. The vasculature of the optic nerves was microdissected and examined under the stereoscopic microscope after injecting their arteries with a 10% mixture of India ink and gelatin, and fixation in a 5% solution of formalin. Results: Intracranial segment of the optic nerve was richly supplied, from both, the ventral and the dorsal side, strictly with penetrating branches which come from the pial arterial network originating from the internal carotid artery and the superior hypophyseal artery for the ventral nervous surface, and from the anterior cerebral artery for the dorsal nervous surface. Conclusion: In accordance with the objective, and based on the obtained results, we confirmed that intracranial segment of the optic nerve has a rich and very delicate vascular network.

When pulp tissue gets exposed, therapy procedures are supposed to promote healing and to ease forming of reparative dentin in order to preserve vitality and health of the pulp. Vital pulp therapy (VPT) procedure includes removal of the local irritants as well as application of protective materials directly or indirectly on tooth pulp. Vital pulp therapy may be used for the treatment of the reversible pulp diseases in order to promote root development and to form apical region which will ensure correct endodontic tooth treatment in later stages. There are numerous controversies concerning vital pulp therapy but mostly related to the choice of the materials, correct technique and evaluation of the final therapy results. The goal of the experimental research is to use scanning electron and polarized microscopy to analyze modifications on cellular and extracellular components of the tooth pulp after direct and indirect overlaying with materials on the calcium hydroxide basis (Calcimol VOCO USA). We will also determine the appearance of dental surface after direct and indirect overlaying and if Calcimol proves good and effective in dentinogenesis, we will propose it for clinical usage. Research has been conducted on experimental animals (pig). Materials used in this research were on calcium hydroxide - base, Calcimol. V class preparation has been applied on the teeth of the experimental group. Eleven teeth have been overlaids directly and the same number of teeth has been overlaid indirectly. After the preparation, materials based on calcium hydroxide have been applied and cavity has been closed with materials from the glass ionomer cement group (FUJI IX GC Japan). Teeth that were treated with pulp perforation had their chambers filled with materials on calcium hydroxide-base and their cavities were closed with glass ionomer cement (FUJI IX GC Japan). Correctly prepared teeth have been observed with SEM and polarization microscopes. Observing and analyzing of the results with polarization and scanning electron microscope in comparison with control group showed that gained results may have significant clinical implication in biological pulp treatment. Directly applied Calcimol observed through polarization microscope points to intensive changes in blood vessels and beginnings of erythrocyte disintegration, distinct extravasation, and appearance of the small necrotic spots. SEM analyzes shows contact of the amalgam-Calcimol without new amorphous dentinal structures. Indirectly applied Calcimol observed through polarization microscope points to newly formed dentinal structures, calcification cores surrounded by huge cells and blood vessels presence. SEM analyzes shows clear border between newly formed dentinal tubules and ordinary dentinal structure. Gained results suggest application of the Calcimol as a material for indirect pulp overlay while its application in indirect overlay isn’t indicated.

Existence of stress at workplace leads to the occurrence of occupational burnout among miners. OBJECTIVE is testing of influence of stress on occupational burnout among miners. METHODS The research was designed as a cross-sectional study and covered 345 subjects, which were classified into three groups: two investigated groups, consisting of Miners A (142), Miners B (147) and Control group (56) consisting of administrative workers. The research was conducted in the Health Center ZveĆan, in the Medical Laboratory Service in ZveĆan and at the Institute of Occupational Medicine in Niš. The following questionnaires were used in the study: Questionnaire on basic sociodemographic indicators of respondents, Copenhagen Burnout Inventory (CBI), and Occupational stress assesment questionnaire. Data analysis was performed using the SPSS 16.0 software package. RESULTS The study of the presence of stressors in the workplace compared to the examined groups showed that a large number of stressors were evident, with the average value of all stressors at miners 2.60 ± 1.02, which is significantly above the average value of all stressors in the control group 1.85 ± 1.02. Above the total average of all stressors 2.60 ± 1.02, there is a large number of stressors. All stressors statistically significantly higher in miners compared to the control group (p <0.001) and the values of each individual stressor in the control group are below the average values of all stressors in miners (2.60 ± 1.02). High burnout level is present in 50.70% of Miners A, 46.90% of Miners B and 16.10% of Control group subjects. It was found that there is a statistically significant difference in the incidence of high burnout in relation to the investigated groups (p <0.001). DISCUSSION There is a large number of stressors among miners and their average value is significantly above the average value of all stressors in the control group. The stressors are both quantitatively and qualitatively different in relation to the control group. A large number of high-strength stressors significantly increases the probability of stress in both groups of miners and contributes to the occurrence of occupational burnout. There is a high exposure to stress among miners, and the impact of stress on occupational burnout has been proven in a large number of research in different professions. This was also confirmed in miners, among whom high exposure to stress led to high occupational burnout, which is statistically significant in relation to the control group. CONCLUSION The results of the study showed that there are a large number of stressors in the miner groups, that the average value of all stressors in miners is significantly above the average value of all stressors in the control group, that there are a large number of stressors that are in strength above the total average of all mining stressors and that all stressors are statistically significantly higher in miners than in the control group. The strongest stressors are most important for stress, and the presence of a large number of stressors above the total average of all stressors not only increases the probability of stress, but also proves a great deal of stress, but also contributes to the intense occurrence of occupational burnout. The results of the study have shown that high burnout is present in about 50% of miners in both mines and that there is a statistically significant difference in the incidence of high burnout in relation to the control group. Occupational stress affects occupational burnout among miners.

The presence of regional metastases of laryngeal cancer differs depending on the location of the tumor and has an influence on the overall survival. The aim of this work is to analyze the frequency and characteristics of regional metastases T1 and T2 of laryngeal carcinoma in relation to the primary tumor location, and their effect on the overall survival. A retrospective study, conducted in the period between 2002 and 2012, that analyzed 445 patients who were surgically treated for laryngeal cancer of T1 and T2 category. The first group consisted of 397 patients without regional metastases, while the second group consisted of 48 patients with regional metastases. A three-year survival is followed, as well as the testing of potential predictors of outcomes by methods of regression. Regional metastases were present in 3.1% of patients with glottic carcinoma of T1 and T2 category, while 43.5% of patients with T1 and T2 supraglottis carcinoma had regional metastases. In the group with regional metastases, there is no statistically significant difference in the occurrence of extracapsular extension in relation to the tumor location, p = 0.7027. The three-year survival rate of patients without regional metastasis is 93.95%, while the survival of patients with regional metastases is 68,75%, p = 0.000. The tumor location (95% CI -1.4716 to -0.0497, P = 0.0369), and the presence of regional metastases (95% CI -1.6300 to -0.0253, P = 0.0443), were identified as predictors of outcomes by multifactorial analysis. Regional metastases in T1 and T2 laryngeal cancer are more common in patients with supraglottic carcinoma. The presence of regional metastases significantly reduces the three-year overall survival.

Youth is a critical age to begin experimenting with alcohol and tobacco, whereby social prestige, self-assertion, relaxation from difficulties, the way of showing rebellion against authority and valid social norms are cited as motives. Consumption of alcohol and tobacco during the period of personality formation leads to permanent behavioral disorders, while the biological characteristics of young people determine the faster development of addiction to these substances regarding to adults. In addition, the social position of young people and the position of their families are extremely jeopardized. The aim of the study was to evaluate the prevalence of tobacco and alcohol use among students of the University of Pristina with a temporary headquarters in Kosovska Mitrovica, i.e. to establish the connection between these habits and the demographic and socio-economic characteristics of the students. The research was done as a cross sectional study on a representative sample of students of the University of Pristina with a temporary headquarters in Kosovska Mitrovica, in March and April 2011. The survey covered 567 subjects. The questionnaire served as a research instrument, the same that was used in researching the health behavior of students from other universities in the Republic of Serbia in 2000. The data were processed using descriptive statistics while the hi-square test was used to analyze the data. Out of the total number of surveyed students, a quarter (24.7%) answered that they were smoking cigarettes, while 91.4% of our respondents tasted alcohol. The highest proportion of respondents from the Faculty of Arts claims to consume cigarettes, students who get 4001-5000 dinars per week, as well as respondents who are "not particularly satisfied" with the their choice of faculty. The highest proportion of male students and students whose weekly pocket is from 2001 to 2000 dinars consume alcohol.

Introduction: Solar or artificial UVA radiation play a major role in photoaging of the skin. Objective: The aim of our study was to determine the presence of morphological changes in the dermis of mouse skin exposed to UVA radiation, with or without the usage of photoprotective cream. Methods: This experiment involved the exposure of female BALBc mice, to solarium UVA lamps. The animals were divided into 2 experimental and 2 control groups. Before the radiation exposure, the hair on the backs of the experimental animals and one kontrol group was removed by shaving 3 times a week, and a half an hour before the exposure a broad spectrum photoprotective cream (UVA filter and SPF 50) was applied on half of the experimental animals. The animals were exposed to radiation 5 times a week, 2 hours a day (the dosage of 156 J/ cm2), for 16 weeks, up to a total radiation of 12500 J/cm2. Results: The presence of impaired collagen fibril network was the most pronounced in the experimental group of animals exposed to radiation without the usage of photoprotective cream (p<0.001). The presence of normal collagen fibril network was observed in the both control groups (p<0.001). The presence of incipient solar elastosis was observed in the experimental group of animals exposed to radiation without the usage of photoprotective cream. Conclusions: The results showed that the usage of a photoprotective cream provided an efficient protection against the effects of UVA radiation and dermal photoaging.