Introduction: The circle of Willis is the major source of collateral blood flow between the carotid and vertebrobasilar system. Its potential depends on the presence and size of arteries that vary greatly among normal individuals and therefore their adequate observation by a radiologist is necessary. Aim: Determine the type of the circle of Willis and their frequency. Determine the type, frequency and localization of anatomical variants of arteries, as well as their average diameter. Compare these variables according to the age and gender of the examinees. Material and methods: A retrospective study was performed at the Center for Radiology of the Clinical Center Nis during 2017. All subjects underwent CT or MR angiography according to a standard endocranial protocol. The anterior and posterior parts of the circle were specially observed, with an emphasis on the presence or absence of anatomical variants of the arteries, with the measurement of their diameter. The obtained data were classified into variants of the front or rear part of the ring as well as the type of ring according to integrity. The frequency of these variables and their comparison by sex and age were measured. Results: The research included 92 examinees. According to the configuration of the Willis arterial ring, the adult type was the most often represented (71.7%). The most common type in terms of integrity was partially complete. The most common anatomical variants obtained in our work was aplasia of AcoA (27.2%) and aplasia of one or both PCoA (21%). PcoA hypoplasia was occured in women with a frequency of 13.5% while in men it was not present. Conclusion: Adequate understanding of the morphology of the circle of Willis by radiological methods is a good guide for neurosurgical and radiological intervention procedures. In this way, potentially significant neurological complications and the risk of morbidity and mortality could be reduced.

Introduction: Maxillary canines are usually impacted teeth the second after third molar. Frequency of impacted maxillary canines is about 1 to 3% of population (in 85% of the cases palataly, and in 15% of the cases bucaly). The aim of this research was to find the frequency of bucal and palatal impacted maxillary canines in relation to sex and position of impacted tooth. Matherial and method: We analyzed three-dimensional computed tomography images (CBCT) of 64 examinees (aged 12 to 33 years) with 80 unerupted maxillary canines to plan the orthodontic therapy. Results: Among 64 examines with impactions, 80 impacted maxillary canines are diagnosed. The average age of all respondents in the survey is 16,3±4,3. Of 64 examinees in research 41(64.1%) were female which is significantly more important than the representation of male examinees whose number was 23(35.9%). Frequency of unilateral impactions of maxillary canines is three times higher 48 (75%) in comparison to bilateral impactions 16 (25%). Of total 80 impacted maxillary canines 19 (23.75%) were bucal impacted, 3 (2.75%) in the middle of alveolus and 58 (72.5%) palatally. With the bucal and palatal impaction usually was represented partially vertical impaction (70%); completely horizontal impaction (10%) was represented only in the palatal impaction. Conclusion: The analysis of CBCT images of maxilla shows a statistically significant frequency of partially vertical, unilateral and paltally localized impacted maxillary canines.

Introduction: Cervical cancer is the fourth most common and accounts for about 6.6% of all cancers in women. Aim: The aim was to determine the frequency of premalignant and malignant changes in the cervix, to examine the histological-cytological correlation of premalignant and malignant changes in the cervix and the correlation of the women's age with the stage of cervical disease. Material and Methods: A retrospective study analyzed 186 cervical biopsy specimens and cervical smears (Papanicolau test) at the Institute of Pathology of the Faculty of Medicine in Pristina, based in Kosovska Mitrovica, over a three-year period from 2016 to 2018. Results: Of the 186 subjects, 62 had mild premalignant changes of type LSIL, 22 HSIL, and as many as 20 (10.75%) cervical cancer. There was a statistically significant positive association between histological and cytological findings (r = 0.854; p <0.001). There was a statistically significant difference in the age of the subjects with regard to histological findings (F = 11,327; p <0.001). Subjects with HSIL were significantly older than those diagnosed with cervicitis chronica (p = 0.029). Subjects diagnosed with planocellular carcinoma were significantly older than women with cervicitis chronica (p <0.001) and LSIL (p <0.001). Conclusion: There is an increasing trend of cervical cancer in Northern Kosovo and in the Serbian enclaves in central Kosovo and Metohija. Subjects with cervical cancer were significantly older than subjects with mild premalignant cervical changes. There is a significant histologic-cytological correlation of cervical findings, so we believe that more massive cervical screening, especially in younger women, could reduce the incidence of premalignant and malignant diseases of the cervix.

Thyroid storm is an acute and severe complication of thyrotoxicosis. It is characterized by high fever, sweating, tachycardia, and often heart failure too. The objectives of the paper is to present the case of a patient with thyroid storm developed after the trauma of the chest at previously apparently healthy individuals, diagnosed on the basis of clinical preview and based on the diagnostic criteria according to Burch and Wartofsky. The most common complication is Mb. Graves - Basedow, but often associated with multi-nodose goiter. Thyroid storm is the most severe form of thyrotoxicosis with a mortality rate of 8 to 25 %. Case report. We present an interesting case from our practice: thyroid storm caused after chest trauma in apparently healthy people, but with unrecognized hyperthyroidism and thyroid gland nodule. Conclusion. The objectives of this presentation were to raise awareness of the association between signs and symptoms of thyroid storm that dominate the clinical picture and complicate the initial presentation and the evolution of the situation caused by trauma. The treatment of hyperthyroidism resulted in conversion in sinus rhythm, withdrawal of symptoms and signs heart failure, and normalization of artery pressure.

Introduction: The occurrence of microalbuminuria in type 2 diabetes mellitus (T2DM) patients is regarded as an early clinical sign of incipient kidney damage. Microalbuminuria is often evaluated as urinary albumin to urinary creatinine ratio (ACR). Aim: To assess determinants of microalbuminuria in T2DM patients without prior diagnosis of nephropathy using ACR cut-off values. Materials and Methods: ACR was measured in a total of 90 T2DM patients, during two months in three non-consecutive days, and routine biochemical analyses were performed, including glycated hemoglobin (HbA1c), serum uric acid (SUA), and atherogenic index of plasma (AIP). The cut-off values of ACR were ≤ 2.5 mg/mmol in males, and ≤ 3.5 mg/mmol in females. Duration of T2DM, history of hypertension, HbA1c, estimated glomerular filtration rate (eGFR), AIP, and SUA were investigated for association with microalbuminuria. Results: According to ACR patients were considered as non-albuminuric (n= 57) and microalbuminuric (n = 33). Compared to non-albuminuric group, microalbuminuric group had increased urinary creatinine, urinary albumin, HbA1c, triglycerides and SUA, whilst decreased HDL-cholesterol levels. Although eGFR was generally reduced, the correlation between LogACR and eGFR was not significant (p > 0.05). However, the correlation between LogACR and LogHbA1c was significant. The multiple logistic regression analysis revealed HbA1c (t = 3.42; p = 0.012) and SUA (t = 2.44; p = 0.040) as independent predictors of microalbuminuria in T2DM patients. Conclusion: At ACR cut-off values, concentrations of HbA1c and SUA were independent predictors of microalbuminuria in T2DM patients not yet diagnosed with nephropathy.

Introduction: Different types of tests present a great part of the academic life, and the tests themselves are extremely stressful situations for most students. The question of strategies used for coping with anxiety in testing situations is raised by the anxiety experienced by students and the levels of their self-esteem during tests. Aim of the paper: The aim of the paper is to take into consideration language anxiety, self-esteem and social and demographic variables as predictors of active use of strategies for coping with the testing situation. Material and methodology: This research included 338 students from five faculties/colleges, with an average age of 21.82±2.561, who were administered the following scales: Rosenberg's Self-esteem Scale, the Coping with the Testing Situation Scale and Foreign Language Classroom Anxiety Scale. Results: The Subscale for Language Anxiety during Testing has the highest reversed predictive value (beta=-0.43, p<0.001) of coping strategies for the testing situation; older respondents have less expressed ability of coping with the testing (beta=-0.23, p<0.001), and the higher the level of fear from negative evaluation (beta=0.21, p<0.001), the more the respondents are coping with the testing situation. Conclusion: The higher the testing anxiety, the less will the students use coping strategies, and the older students cope less with stressful testing situations, but the greater the presence of a more expressed fear of inefficiency, the more will the respondents cope with the testing situation through various strategies.

Objective: In the available literature data, there is not much information about problems of patients with end stage kidney disease in relation to oral health. Our objective was to show the importance of oral diseases for patients on hemodialysis. Data sources: In this review article, the sources of data are review articles and scientific articles in the English language published in MEDLINE database. The choice of studies was based on keywords: Chronic kidney disease, Hemodialysis, Oral health, Periodontal diseases. Results: It is assumed that almost 90% patients with chronic kidney disease manifest some symptoms of oral disease. Therefore, it is important to determine the impact of periodontal disease on the progression of kidney failure in these individuals, to evaluate inflammatory parameters in this patient population, to assess the degree of bone loss and periodontal disease index, to determine the presence of bacterial strains, paradontopathy of gingival fluid and antibody titers, to examine correlations of proinflammatory cytokines in the gingival sulcus and serum, as well as to determine the relationship between periodontal tissue and inflammatory mediators. Periodontal diseases can increase the possibility of developing chronic kidney disease by 1.5 to 2 times. These oral diseases include gingival hyperplasia, periodontitis, xerostomia, unpleasant breath, changes in the oral mucosa, malignancies, oral infections, dental abnormalities and bone lesions. Conclusion: This requires serious cooperation between nephrologists and dentists to make proper communication possible, in order to provide quality dental care for this growing patient population in accordance with new treatment strategies.

Introduction: Obesity is one of the seven leading risk factors for the occurrence of the most common non infectious diseases. An epidemic model of the obesity prevalence increase is also present in the student population. To identify an overweight person, who has an increased relative risk status and who did not develope clinically manifested cardiometabolic disorders is a critical moment for the effective obesity prevention and treatment program. Objective: To determine the prevalence and status of relative risk of developing overweight related diseases among students at the University of Pristina-Kosovska Mitrovica. AUTORI SAŽETAK ENGLISH ORIGINALNI RADOVI Uvod: Gojaznost je svrstana među sedam vodećih faktora rizika za nastanak najčešćih nezaraznih bolesti. Epidemijski model povećanja prevalencije gojaznosti prisutan je i kod studentske populacije. Prepoznavanje osobe sa prekomernom težinom koja je u statusu povećanog relativnog rizika a kod koje se još uvek nisu razvili klinički manifestni kardiometabolički poremećaji je poslednji trenutak za efikasan program prevencije i lečenja gojaznosti. Cilj rada: Odrediti prevalenciju i status relativnog rizika od razvoja bolesti povezanih sa prekomernom uhranjenosti među studentima Univerziteta u Prištini-Kosovska Mitrovica. Metode rada: Procena stepena relativnog rizika od razvoja bolesti povezanih sa prekomernom uhranjenosti rađena je na osnovu izmerenog indeksa telesne mase (BMI-Body mass index), obima struka (WC-Waist circumference) i kombinovano BMI sa WC. Rezultati: U ispitivanju je učestvovalo ukupno 1686 studenta (44,4% muškog pola i 55,6% ženskog pola). Srednje vrednosti telesne težine, BMI i WC bile su ispod vrednosti korišćenih tačaka preseka. Status povećanog relativnog rizika od pridruženih bolesti je imalo: prema BMI-20,2% studenata (27,8% muškaraca i 14,1% žena); prema WC-12,6% (12,2% muškaraca i 12,9% žena) i prema BMI sa WC-20,2% (27,8% muškaraca i 14,1% žena). Postoji značajna razlika u stopi prevalencije koji su u statusu visokog i veoma visokog nivoa rizika u zavisnosti od metode procene (samo prema BMI i prema BMI sa WC). Zaključak: Utvrđena je visoka stopa prevalencije predgojaznosti i gojaznosti, opšte i abdominalne među studentima Univerziteta u Prištini-Kosovska Mitrovica. Oni se mogu svrstati u grupu studenata sa statusom povećanog relativnog rizika od nastanka i razvoja bolesti povezanih sa prekomernom uhranjenosti. Savetovalište za ishranu i dijetetiku u okviru Studentskog centra prema njima mora intenzivirati mere prevencije i eventualnog lečenja gojaznosti.

Introduction: Acute myocardial infarction is a common and urgent disease with potentially poor prognosis, so the examination of the quality of life of diseased and all factors that affect it are very important. Objective of the paper is to examine the impact of the characteristics of the health issues, thelength of time since the myocardial infarction as well as the comorbidity to the quality of life of diseased of myocardial infarction.

Methods: In order to assess the impact of acute myocardial infarction on the quality of life of diseased, a retrospectiveprospective study was conducted, designed as a cross sectional study. The followingwas used during the research: sociodemographic questionnaire, questionnaire for assessment of health status, comorbidity and characteristics of health issues of patients and Short Form 36 Health Survey, i.e. SF-36. Statistical analysis of data was made using the SPSS software statistical program.

Results: The study covered 175 subjects, of which 113 (64.6%) were male and 62 (35.4%) female. In relation to the time of diagnosis of AMI in 29.7% of subjects, the diagnosis was set in the last month, while in the remaining 70.3% it was diagnosed in the last year to a month. The highest number of respondents (68.6%) felt a strong pain before reporting to a healthinstitution for treatment, 63.4% of the respondents had cardiovascular comorbidity and the highest number of respondents (83.4%) has diagnosed arterial hypertension. Physical functioning (65.48: 81.42) (t = -6.841; p = 0.001), limitation due to physical health (51.44: 76.62) (t = -7.364; p = 0.001), the presence of bodily pains (35.88: 57.05) (t = - 7.943; p = 0.001), general health (59.04: 75.75) (t = -7.277; p = 0,001), vitality (52.78: 56.99) (t = -4.796; p = 0.001), social functioning (39.42: 63.31) (t = -7.099; p = 0.001), limitation due to emotional problems (33.97: 61.51) = -6.693; p = 0.001) and mental health (36.69: 53.97) (t = -7.714; p = 0.001) are domains in which there is a high statistically significant difference in mean values between groups of subjects compared to the time of diagnosis, whereby respondents which diagnosis was set in the last year to a month have statistically significantly better quality of health compared to those which diagnosis was set in the last month. When it comes to a common measure of physical health and mental health, a group of subjects diagnosed in the last year to a month also showed statistically significantly better results than respondents in whom AMI diagnosis was found in the last month (t = -4.152; p = 0.001; t = -7.147; p = 0.001).

Discussion: The quality of life related to health is significantly lower in subjects diagnosed with AMI in the last month compared to respondents who have been diagnosed in the last year to a month and between groups of subjects of different sexes there is no statistically significant difference in any of the quality life domains related to health. When it comes to the age of respondents, HRQOL is significantly higher in all domains of physical and mental health in the younger group of respondents.

Conclusion: Myocardial infarction affects the quality of life of the diseased,which is significantly better in the younger age group compared to the older respondents, and does not differ in relation to gender. The quality of life of patients with myocardial infarction differs in relation to the time since myocardial infarction and those diagnosed with AMIduring the reception to the hospital in the last month have significantly lower quality of life compared to subjects with AMI diagnosed in the last year to a month. The quality of life of patients with myocardial infarction is worse if the health issues are more expressed and there is comorbidity.