The aim of our work was to inquire after frequency and characteristics of repeated myocardial infarction. We questioned prospectively 123 patients, diagnosed with acute myocardial infarction, who were hospitalized in the Coronary unit
of Krusevac Health centre, during the period of 01. 02.- 31. 07. 2001. Repeated myocardial infarction was found in 16,26%
of questioned patients. Non Q acute myocardial infarction was found in 35,00% on patients with repeated myocardial infarction and 8,74% on patients with the first myocardial infarction (p<0,01). In patients with repeated myocardial infarction
more often was found heart failure (55,00% vs 20,39%, p<0,01). Repeated myocardial infarction have difficulty clinical
flow, but have not statistical significantly higher early mortality

In this research it was examined how fatigue in the working process affected the speed of reaction on a complicated
stimulus, and also on the frequency of inadequate reactions. The investigation was carried out by means method of combine
reaction time (CRT). CRT is the shortest time that passes from the moment when a person is affected by a complicated stimulus until the moment when the person responds to the stimulus, by making adequate and complicated reaction. CRTwas registrated in working population of railroad employees who were divided in two groups:group of locomotive drivers (n= 44) and group of a railroad employees (n=25). In the group of locomotive drivers it was taken into the consideration whether the type of locomotive was electrical or diesel power. In both groups, CRT was registrated in two phases of working process; before and after daily work. Results showed that in both examined groups CRT got significantly extended after the
working process. Duration of CRT was longer before and after working process in the group of electrical power locomotive
drivers compared to diesel power locomotive drivers. Fatigue did not affect significantly on the frequency of incorrect answers

Menopause may influence negatively the cardiovascular system of women, especially that of smokers. The aim of
our study was to compare lipid levels and left ventricular function in postmenopausal women smokers and non-smokers
during 12 months of oral estrogen replacement therapy. The study group included healthy postmenopausal women, 30
smokers and 32 non-smokers. Before and in 6 month intervals the following parameters were followed: total cholesterol,
LDL-, HDL-cholesterol, triglycerides, blood pressure and echocardiographic parameters of systolic and diastolic left
ventricular function. Before therapy non-smokers had higher total and LDL-cholesterol, when compared to smokers. Oral
estrogen replacement therapy significantly decreased levels of total and LDL-cholesterol and increased HDL-cholesterol,
only in non-smokers. No change in lipid levels was observed in smokers. However, women who smoked longer had higher
triglyceride levels after 12 months of oral estrogen replacement therapy. Echocardiography revealed significant improvement of systolic and diastolic left ventricular function in non-smokers, while improvement of only systolic function in
smokers. Our study has shown that 12 months of oral estrogen replacement therapy may not have a protective role on the
cardiovascular system of postmenopausal women smokers

The research was conducted at the Department of Pathology and Histology of Clinical center of Novi Sad. We analysed the reports of autopsies of newborns (to 28 days old), stillborns and miscarried fetuses in 1991 and 2001. Found
malformations were classified according to organ systems. Results for 1991 show next structure of congenital malformations: 3 malformations of central nervous system (14.29%), 0 malformations of urogenital system (0%), 3 malformations of
gastrointestinal system (14.29%), 1 malformations of musculosceletal system (4.76%), 9 malformations of cardiovascular
system (42.86%), 1 chromosomal defects (4.76%), 4 multiple malformations (19.05%). Results for 2001 have next value: 9
malformations of central nervous system (27.27%), 4 malformations of urogenital system (12.12%), 5 malformations of
gastrointestinal system (15.15%), 0 malformations of musculosceletal system (0%), 4 malformations of cardiovascular
system (12.12%), 2 chromosomal defects (6.06%), 9 multiple malformations (27.27%). By the comperison of the results of
structure of congenital malformations in 1991 and 2001, we can conclude that the differences of cardiovascular and urogenital malformations are statistically important

The frequent sign in renal disease and disease of urinary tract is presents of blood in urine, hematuria, and it is discovered very often in children. Aim of this work was to establish the most frequent causes of hematuria in our recorded
material. Investigation was accomplished on 60 patients, by using standard clinical and biochemical methods. The results of
work have showed that hematiria may be faund in any age in children. Most patients belong to age 5-10 years 27 (45.0%),
belong to age up to 10 years, and 26,6% belong to age 1 -5 year. Hematuria is more common in school-aged children and in
adolescence. Gross hematuria is found in 60% of patients, and microscopic hematuria in 40% of patients. Infective cause of
hematuria is found in 29 patients, and in 31 patients other causes, such as : stones, sec.glomerular diseases, tumors, hematologic disorders, etc. As infective glomerular disease and infection of urinary tract, in 25 % patients the cause of hematuria is acute poststreptococcal glomerulonephritis, tuberculosis in 6,66 patients,urinary tract infecion in 16,6 patients (in 8,33% patients caused by E.colli). Anatomic abnormalities is found in 15% patients,asymptomatic hematuria in 6,6%, lithiasis in 5%, and Henoch - Schönlein in 5%, and coagulopathies in5 % of patients, other causes are rare.In observed sample of patients, we have registrated high frequency of hematuria in chlidren with ac. poststreptoccal glomerulonephritis, then in children with morphological abnormalitis of urinary tract,urinary tract infection, and IgAnephropathia as a very rare cause, but Trachtman and Hagg in their reserches found Alport syndrom and IgA nephropathy as a most frequently causes of Hematuria

Powers was the first scientis who described Varices oesophagei in 1939 (Thomas in 1960) in the 19th century,
th Varices weve considered like consequence of splenies sicknes, was noted like 20 century, portal hypertension, noted like
pathogenesiscal machinery for begining. Varices oesophegei and classification. Oesophagoscopy was vade by 40 patients
because varices were veryfied and a factor of risk, which varices have was measured. Endoscopy morphologycal classification Varices oesophagei was used by Paque in 4 class. Varices in the first class was had 17,5% in the second class 35%, in the second and third class 22,5%, the fourth class 5%. Varices in the third and fourth class have observed like bigs Varices who have very risc and ruinouses for life.

On the territory of Yugoslavia Q fever presents a significant health and epidemiological problem. In Vojvodina Q
fever is being reported in epidemic form. In adition to, sporadic cases are registrated in Central Serbia as well. In Kosovo and Metohia during this period there was no single case of Q fever diagnosed. This disease is primary professional illness. Q
fever is more often diagnosed in male compared to female gender. Among reported cases elderly structures between 20 and
59 dominate and participation of those elderly groups estimate 78,4% of all registerd cases. Q fever has a strictly seasonal
character, and the most cases are reported in the period January-April

Hepatitis A is relatively benign disease. The duration of illness caused by HAV is variable, ranging from several
weeks to several mounths. Infection with HAV does not cause chronic liver disease. We have presented the clinical and
st epidemiological caracteristic an epidemic of hepatitis A in area of Toplica. Since late septembar 2001 to february of 21 in
2002, in hospital in Prokuplje have been treated 211 patients. The epidemic is spread by contact

Specific immunotherapy (SIT) has been used for almost a century but its form of administration is still a matter of
debate. At present curative SIThas only demonstrated its efficiancy, under the conditions that an appropriate allergen extract
is used, and patients are careffuly selected. However, many alergic patients likely to respond to immunotherapy are not
treated specificaly, due to the prevaling opinion that immunotherapy is ineffective, and has more uneffectable side effects
than drug treatment. Direct comparison of efficiancy between immunotherapy and drugs is problematic as this implies a
comparison between a treatment aiming at interfering with the pathophysiological mechanisms of the alergic inflammation
with potential for long term effect, or even cure (immunotherapy), and a treatment abolishing symptoms whi-le being
administered, but without long term preventive capacity (drugs). In most patients the situation is not an either but ra-ther
both and. The advantages of combinig immunotherapy and drugs are related to a higher likelihood of increasing effi-ciancy,
reducing side effects, and improving patient compliance by combining a treatment having an immediate effect with one
functioning more slowly

Nosocomial infectious (NI) are very big problem nowdays. The aim of this was to investigate the level of knowledge of medicial students of University Pristina about NI and to compare the knowledge level of preclinical with knowledge level of clinical students about NI. Cross-sectional study was conducte in May 2001. The instrument of survey was questionnaire with 28 questions wich were distributed to all third-year (preclinical) students and to all fifth-year (clinical) students and to all fifth-year (clinical) students at the Medical Faculty Pristina. The majority of third-year students (78,2%) and fifth-year students (91,1%) knew the definition of NI and their reservoirs (100.0%). The fifth-year students gave correct answers, statisticaly significant, more frequently (X} =4.62; df=1, p<0.05). The majority of students (89,1% of third-year and 96,4% of fifth-year students) knew that NI could be prevented, but only 14,5% of third-year and 25% of fifth-year students considered handwashing the basic measure for prevention, although there is no statisticaly significant difference between third-year students (X' =2.62; df=1, p>0.05). Around 98% students percepted the risk of NI for medical staff. Around 80% of students estimated that the aditional lectures about NI are needed during the studies. The fifth-year students more frequently showed higher level of knowledge about multidrug-resistant bacteria (X* =17.77; df=1, p<0.01).

Approximately 70% of third-year students gained knowledge about NI from sources other than lectures, but 75% of fifth-year students gained that knowledge from lectures in epydemiology. Additional information about NI, especially about univesal precution, is needen for medical students. Tt is very important to appropriately organise the studies with more practical work in prevention of NI. The emphasise should be put on health edecation in order to increase knowledge about NI, general hygienic measures encouraging handwashing and correct use proper dezinfectans in order to control the hospital environment.