Parameters of anaerobic capacity were investigated in the group of 90 young subjects classed into diferent groups depent on their physical fitness. The group consisted of 30 wrestlers, 30 rowers and 30 students. Basic antropometric parameters were taken for each person and than Wingate anaerobic test was administrated. The aim of this investigation was to measure anaerobic parameters and determine weather there was a difference among sportsman and non sportsman. All parameters of Wingate test (anaerobic power, explosive power, anaerobic capacity) were significantly higher in the group of sportsman. (p0.05) Also, the highes values od anaerobic parameters were detected in the group of wrestlers, since this is typicaly anaerobic sport. The lower values were measured in the group of non sportsman, as expected.

Anorectal abscesses and fistulas are problems that are commonly encountered together. Occasionally, their management can prove to be formidable, constantly challenging the clinical and surgical skills of the practicing surgeon. This article reviews the etiology, presentation, and treatment of anorectal abscesses and fistulas.

There are different reports regarding the characteristics of examined quality of life (QOL) in patients with combined coronary and valvular surgery. Objective was to compare the quality of life changes after isolated coronary and associated coronary and valvular surgery. From February to May 2002, we prospectively studied 243 consecutive patients, who underwent elective CABG. The Nottingham Health Profile Questionnaire part I (NHPpart I) was used as a model for QOL determination. NHPpart I contains 38 subjective statements divided into six sections: physical mobility (PM), social isolation (SI), emotional reaction (ER), energy (En), pain and sleep. The scores ranged from zero to 100, by adding the item weight, determined by Thurstone method of paired compares, to every positive answer. We distributed the questionnaire to all patients before and six months after CABG. Two hundred twenty six patients filled in the postoperative questionnaire. An isolated coronary heart disease was present in 218 patients (89.71%), and associated coronary and valvular disease in 25 patients (10.29%). Preoperatively, there is no difference in QOLamong the examined groups. After operation, quality of life was improved in 84.65% (171/202) of patients using coronary surgery and in 79.17% (19/24) of patients using combined (coronary and valvular) surgery. Quality of life was statistically improved in the first group of patients in all sections, and in the second group of patients in 4 sections (PM, En, pain and sleep) (p<0.05). There is no significant correlation between the quality of life changes after operation and the type of surgical procedure. By univariate and multivariate logistic regression, combined procedure distinguished as the independent predictor of QOL worsening in the ER section (p=0.012, OR=3.62, 95% CI 1.32-9.92). Six months after CABG quality of life was significant better in most of patients in both studied groups. Associated coronary and valvular surgical intervention distinguished as the independent predictor of quality of life worsening in the ER section.

Although nowadays is importance of surgery as primary method of gestational trophoblast disease treatment smaller than earlier,appliance of the surgical procedure is still valuable addition to the modern therapy of these diseases. We present a patient with mola hydatidosa where hysterectomy had been done as operative way of this disease treatment.

In essential hypertension, hemodynamic changes in systolic and diastolic function acompany left ventricul hypertrophy ussualy. Both of these cardiac function can be detected with echocardiography and were measured during this study. 23 patients with moderate essential hypertension were treated with cilazapril plus small doze of diuretic (hydrochlorothiazide) once daily for 120 days. On the begining we found diastolic disfunction, but after the treatment there was a significant improvement in isovolumic relaxation time, early diastolic filling pattern and normalized left ventricular early/ atrial filling ratio. Cilazapril + diuretic combination in a dose once daily controlled blood pressure satisfactory, too. Parameters of systolic function were in the normal levels and there were no significant changes between the two determinations. Thickness of the interventricular septum and posteroinferior wall did not change significantly after 16 weeks of therapy, probably because of too short time of investigation.

Ahigher concentrations of microorganisms in the vagina can lead to preterm delivery. Bacterial vaginosis is a well known risk factor of preterm delivery. Aim of this study was to estimate the presence of bacterial vaginosis as a potential cause of preterm delivery relative to the patients with term delivery, as well as to define the type of present bacteria. The results of our investigation showed more frequent presence of bacterial infection of the vagina in the patients with preterm delivery. The following bacteria have been cultured in the group of patients with preterm delivery: Streptocossus agalctiae, Enterococcus, Staphylococcus sp. and Escherichia coli. In prevention of preterm delivery, we recommend a routine screening of pregnant women (such as obtaining smears to bacterial infection) as well as administration of the therapy in case of positive findings, particularly in those presenting a risk for the development of bacterial vaginosis and preterm delivery. 

In well organized societies, accept of material and technical progress, planning of the family and existing of human resources is of great importance. Every civilized society is tancing care of human potential, planning and progress, eather to stimulate or control of natural increase are bringing the suitable demographics of standards. With better family planning asspecially motivatiy the couples to decide for reproduction and delivering of optimal namber of children in optimal period between deliveries and in optimal ages, brings to decreased mortality among new-borns, and also their mathers. 

It is known that the intoxication with heavy metals and pesticides is most often unmedical poisoning. In contrast to other heavy metals, for example: mercury, lead, cadmium and zinc, toxic copper activity and the mechanism of its effect are not known enough and they are not yet explained. Because of that, the aim of this work was ( with acute dog intoxication with copper sulfate ) to contribute to better clearing of biochemical mechanism as a result of copper toxical effect and to make analysis of its tissue distribution. Researching was done on adult dogs, both sexes, different races and body mass of 14- 20 kg, who were given a 10% water solution of copper sulfate in the dosage of 33mg/b.m. divided into 5 equal doses. The analysis of biochemical blood structure took the following things: total proteins, albumins, globulins, total lipids, chole2+ sterol, glucoze, transaminase (AST,ALT), catalase, peroxidase, vitamin C, proteine SH, the contretation of Cu in the serum 2+ and the content of Cu in the tissues. The results are presented in the charts and graphic presentation. All these changes can be the important directions in an biological monitoring as a biochemical indication of copper pollution in the surroundings.

Stress ulcer presents acute lesion of gastric mucosa, which resulted from influence of different stressors: trauma,
shock, burns, drugs administration, various irritants etc. Since pathogenesis of stress ulcer is not completely clarified, the
most adequate therapy for the patients which suffer from it, is not defined yet. Esomeprazole is a S-isomer of omeprazole
and is the first inhibitor of proton pump synthesized as an isomer. Our aim was to test effects of esomeprazole, given during
pretreatment and posttreatment period, on progress of alcohol induced stress ulcer lesions. We had experiments on sexually
mature Wistar rats weight 200-250 g. Alcohol stress was induced by intragastric administration of 1 mL 96% alcohol.
Alcohol stress produced massive submucosal lesions in glandular part of stomach. Macroscopic lesions were verified
histologicaly. Intragastric pretreatment administration of esomeprazole (20 mg/kg BW) significantly (p<0,001) reduced gastric lesions. Intragastric post-treatment administration of esomeprazole (20 mg/kg BW) did not reduce gastric lesions. Esomeprazole (20 mg/kg BW) administrated in pretreatment period of alcohol induced stress significantly decreased dimensions of stress ulcer lesions in rats, while the same dose administrated in posttreatment period did not cause that effect.

Nuclear magnetic resonance (NMR) or magnetic resonance imaging (MRI) today is the most powerful review method of a human body. Method is based on effect strong magnetic field and on demonstration of natural physical characteristics of nucleus. Hydrogen atom is a part of almost every compound in our body (water, lipids, proteins and nucleid acids).
When we exposed body to strong magnetic field hydrogen nucleus orients in direction of field, which cause resonance and
6 8 emission of radio signals. Resonance frequency for MRI is in range from 10 Hz to 5x10 Hz, which is equal to energies from -28 -25 6x10 J to 3x10 J.