Current issue
Volume 53, Issue 4, 2025
Online ISSN: 2560-3310
ISSN: 0350-8773
Volume 53 , Issue 4, (2025)
Published: 30.06.2025.
Open Access
All issues
Contents
01.01.2005.
Case Reports
PENIS INJURY CAUSED BY A BITE
Considering the fact that there are freer and more varying sex activities, we have today more varying genital organs injuries both at men and women. We present you a patient with two penis injuries caused by a bite. It must be done a complete wound treatment with ATprotection and maximum antibiotics appliance. It is necessary to perform an AIDS test.
G. Stefanović, D. Ivanović, D. Petronić
01.01.2005.
Case Reports
LUXATIO TESTIS
The authors present you two cases of luxatio testis. Luxatio testis is a very rare injury caused by the influence of some strong force or blow. Testicle is luxated in ingvinal chanal, perineum, subcutanue penis tissue and rarely abdomen. Conservative surgical treatment always have to be done
D. Petronić, G. Stefanović, D. Ivanović
01.01.2005.
Original scientific paper
LUTEAL PHASE DEFECT IN WOMEN WITH HYPERPROLACTINEMIA AND UNKNOWN REASON OF INFERTILITY
Luteal phase defect is disorder of low progesterone secretion (low level), or very short luteal phase (shorter than 11 days). Consequence of that is late endometrium maturation, almost 2 days. Such endometrum impedes and makes impossible ovum nidation. Today we have luteal phase defect in 14% of infertility women, and in 21% of women of unknown infertility reason. This has been frequently seen in women with spontaneous abortion and hyperprolaktinemia. Diagnostic methods of DLF are biopsy of endometrium and measuring of progesterone level. The aim of this study is the examine endometrium maturation disorders. The study includes 30 women that are hospitalized in Clinical of Gynecology Pristina. Unknown reason of infertility and normal hormonal status had been in 13 (43%), and hyperprolaktinemia in 7 (56,7%) of women. Histological verificated ovulation had been finding out in 60%of women. Late endometrium maturation, luteal phase defect, had been verificated in 23,3% of women, from there in 29,4% of hyperprolaktinemic women and in 5,4% of women of unknown infertility reason. There was evidence of late endometrium maturation of 2 days (85,7%). and of 4 days th (5,4%). Progesterone level in DFLthe 20th day was 30 nmol/l, the 24 day of menstrual cycle was 28,8 nmol/l. Progesterone level in women with histological proved regular endometrium maturation was higher and it was 45, nmol/l. The lowest progesterone level that can be find in good functioning of luteal body was 31,8 nmol/l.Citohormonal findings in DFL was showing progesterone domination. Take a look at infertility and ovarian function must not be concern only on ovulation, it must take care of endometrium maturation.
L. Vitković, Z. Anđelković, B.N. Mitić, S. Stanišić, M. Dunjić
01.01.2005.
Original scientific paper
SIGNIFICANCE OF THE FISTULOGRAPHY FOR OPERATIVE TREATMENT OF THE FISTULA-IN-ANO
Most fistula-in-ano arise as result of chronic infection of an intersphincteric anal glands and persistence may be related more to non-specific epitelisation of the track. Preoperative definition of the anatomy of the fistulous track and the internal opening plays a primary role in adequate planing of the operative approach to minimize iatrogenic damage of sphincters and fistula recurrence. The diagnosis of anal fistula generally is straightforward and is based on clinical features. By
using palpation of the perianal area, digital examination, and careful probing of the track, the fistula anatomy was defined.
Fistulography, radiografic evaluation, is not routinely indicated in the initial avaluation of fistulas but may be helpful in identyng an occult cause of recurrent or multiple fistulas or if examination is suggestive of inflammatory bowel disease. AIM:
is evaluation of importance of the fistulography for surgical treatment of the fistula-in-ano. The study is prospective. In includes 60 patients divided in two groupies, each 30 patients. Examined group was operated after clinical findings by using
careful probing of the track and fistulography. Control group was operated after clinical findings by using careful probing of the track. In patients, examined group, treated with fistulography allowed a corect diagnosis of primary track 43.3%, secondary track 40.0%, horseshoe track 50.0% and internal opening in 40.0% of patients. The clinical findings, in the same group patients, allowed diagnosis of primary track 76.6%, secondary track 60.0%, horseshoe track 100% and internal opening in 73.3% of patients. Preoperative definition of fistulous track and internal opening by physical examination and its relationship with anal sphincters are important factors influencing the results of surgical management. We do not recommend routine fistulography in the diagnosis of fistula-in-ano.
N. Moljević, M. Vuković, R. Veljković
01.01.2005.
Original scientific paper
MERCURY VAPOR AIRPOLUTION AND THE XI th GROUP OF DISEASES BY ICD - 10 REVISION
In process of chlorine-alkali electrolyze the big mercury failure exist in vapor shape, which across respiratory system, expire in exposed persons organism. The aim of the work was to examine connection between mercury vapor air pollution and sicknesses coming from diseases belonging to the XI group of diseases by International Classification of Diseases th (ICD) - 10 revision. Exploring groups were workers “Kalium chemistry” factory and administration at CI ”Zupa”. Recognized diagnosis on periodical exams year 2000, 2002 and 2004 were entered in reports (expertises) analyzed later on. Analyzed reports for total 571 examinees were done, 184 examinees year 2000, 191 examinees year 2002 and 196 year 2004. As of diagnosis recognized the diagnoses were separate for diseases belonging to XI ICD group. Examinees were divided in a four group according to the grade of exposure: I group day by day exposed; II group sporadically exposed; III group earlier
exposed; IV group not exposed. First, second and third group of examinees were workers of “Kalium chemistry” factory. It was established during the examination at rooms were exposed workers stay that only mercury vapor pollution 3.01 overcomes Maximum Permitted Concentration allowed by JUS. The frequency differences testing between groups according to the grade of exposure, like as frequency differences testing of sicknesses between all exposed opposite un-exposed, showed
to us that differences are statistically significant. Based on the results of the this research it can be conclude that connection exist between mercury vapor air pollution and sicknesses coming from diseases belonging to the XI group of diseases by ICD.
A. Ćorac, G. Trajković, S. Samardžić, A. Milovanović, J. Lekić
01.01.2005.
Science Reports
STATINS FIRST LINE IN THERAPY DISORDERS METABOLISM LIPIDS IN PATIENT WITH DIABETES MELLITUS TYPE 2
.
Diabetes mellitis,type 2 is often associate with disorders metabolism of lipid. That is base for development athero sclerosis, coronare disease and peripheral vascular complications. Patient with diabetes earlier get cariovascular disease. Frequency in equllent in female and male sex. Atherosclerosis is proces which is started earlier in patiens with diabetic, than in healthy population. So, prevention of cardiovascular disease is very important. When we elimination risk factors: smoking, hypertension and lipids, we will reduce coronary syndrome.The clinicly studies show us that the statins drugs are choice for prevention and controle metabolism lipids in these pations. Statins drugs had been show us the best therapy the efects on evolution of atherosclerosis plaques, reversed endothel disfunction and modulation of thrombotic parametars
T. Novaković
01.01.2004.
Original scientific paper
DEYING OF ELASTIC TISSUES WITHOUT DIFFERENTIATION: NEW, QUICKLY METHOD
Our methodological procedure established successful technique of the direct dyeing of elastic fibers and lamellas in elastic tissues. Experiments were carried out on a human autopsy material. Blocks rich in elastic fibers were fixed by 10% buffered neutral formaline and cut in the thickness of 5m. Deparafining of slides is done by xylol treatment (2x15min). Additional denaturation is achieved by combined solution, which contains 1.2g of picric acid in 30% solution of glacial acetic acid. By chloramine B application as blocking agent in form of 1% DMSO solution the dyes affinity for eviromental tissue is decreased. Tissues prepared in this way are treated with 0.5% solution of acidic sulfonic color Evans Blue (C.I.23860) in ratio 2:1. Lamellas are dark violet with light violet periphery. Obtained results speak in favor of high applicability of this method in light microscopy. In our opinion, this method can be recommended as one of methods for identification of elastic tissues.
M. Abramović, R. Pavlović
01.01.2004.
Original scientific paper
HISTOCHEMICAL LOCALISATION AND ACTIVITY OF DPP IV IN ANTIGEN STIMULATED TONSILLA
Dipeptidyl peptidase IV is ecto-enzyme which is present on the cell surface of large number of cells and particularly of T-lymphocytes. It takes part in immune reactions and regulation of immune response, while antigen stimulation of cells increases percentage of expression of DPPIV on their cell surfaces. Since the immune response is different for chronic tonsillar disease of tonsilla palatine, idiopathic tonsillar hyperplasia ITH and recurrent tonsillitis RT, and considering the fact that DPPIV takes part in activation of T and B-lymphocytes stimulated by antigen, we presume that different activities of DPPIVexist in tonsillis and blood of persons diseased of different types of chronic tonsillitis, ITH and RT. The main goals of research are determination of activities of DPPIV on lymphocytes of tonsillas and serum of persons diseased of ITH and RT as well as histochemical and immunohistochemical determination of DPP IV localisation on lymphocytes of examed tonsillas. Two groups of patients are included: nineteen persons with ITH and thirteen persons with RT, while the control group was contained of thirty nine persons with diagnosis systematic lupus erythematosus (SLE) and fiftteen health persons. The research was done on 32 tonsillas created by tonsillectomia of persons with ITH and RT and 86 blood samples of all 86 persons. The results of research show histochemical localisation of enzyme activity of DPPIVin T-dependent zones of tonsilla and it is originating from activated T-lymphocytes. The enzyme activity of DPP IV on tonsillar lymphocytesis is higher in case of IHT compared with RT. By this research we conclude that deifferent activity of DPPIV on tonsillar lymphocytes for ITH and RTpresumes the difference of immuno response of tonsillas during these tonsillar diseases.
S. Savić, S. Savić, V. Avramović, V. Vlahović
01.01.2004.
Case Reports
PHLEGMONA PERIURETHRALIS
We presented you six patients suffering from phlegmona periurethralis. It is mens' disease and, in the greatest degree, it appears at stenosis and urethra trauma. The commonest case of this disease are patients suffering from diabetes and those who carry catheter all the time. The appliance of a large doses of antibiotics and early incision with drainage can help patients to be cured. Urine derivation is very important and it must be like minimal cystostomy
D. Ivanović, D. Petronić, G. Stefanović
01.12.2004.
Professional paper
COMPLEMENT - ACTIVATION, REGULATION OF ACTIVATION AND BIOLOGICAL ACTIVITY
The complement system (complement) involves over 30 circulating and membrane-fixed proteins with an effector
role in the innate and humoral immunity. These proteins help the function of antibodies to protect the organism from foreign
molecules (antigens) which the term complement comes from. Soluble proteins of the complement system made mainly in
the liver and circulate in blood in an inactive form. The activation of complement may be initiated in three ways (classical,
alternative and lecitin pathway), and it is realized by sequential proteolysis of complement proteins (proenzymes) which
become emzymes with the proteolitic activity after cleavage. Products of the activatin of complement bind to the surface of
microbes or to the antibodies bound to antigens. An activated complement shows a number of biological effects, such as
lysis of an attached cell, opsonization, neutralization of viruses, inflammation, clearance of immune complexes etc. In contrast of microorganisms, human cells have a number of regulatory proteins which prevent the complement activation and in that way, they regulate its activity
Z. Anðelković, M. Mirić, V. Nestorović, Z. Milanović, R. Mitić