In this work we present a basic aspects of ionising radiation (afterward of depleted uranium), this effects to human organism, esspecially on radiobiological, health effects on human skin. Health effects ionising radiation on skin depends of its doses. High doses given stron reaction, already in a few days after radiation, and later manifestations arise after longer exposition lower doses this radiation. In this work we present a basics pathophysiological aspects, without specifical clinical manifestations of radiation dermatitis.

Ocular changes at the patients on dialysis are numerous but unique,too. They are caused by primary end-stage renal disease, influence of dialysing itself and regular co-morbid condition. Purpose of this study is to indicate specific ocular finding among patients who are on dialysis. This prospective study assessed 81 patients on regular, chronic dialysis. They underwent complete ophthalmologic examination. The most common findings were the following: conjunctival calcification (53 eyes), cataract (43 eyes) and retinal microangio-pathies(atherosclerotic, hypertensive and occlusive-in total 168 eyes). All findings mentioned above were statistically significant (p<0. 001) regarding to normal population. Ophthalmologist must be familiar with those abnormalities what is necessary for pointing out on special systemic co-morbid condition at the patients on dialysis.

By this investigation an attempt has been done to explain the existence of fear in adolescents from stomatological treatment, by appraisal of fear through its two components (congenitive and physiological). Congenitive component of fear,
was followed by written questionnaire before the first stomatologic intervention (by the standard scale of general anxiety). In the investigation participated 100 adolescents. On the basis of analysis of the question mark the adolescents have been
placed into three groups: normal, pathological and increasingly anxious. During third visit (three stomatologic interventions) each patient was recived the placebo (vitamin C one half of the tablet, orally, 30 minutes before start of work of stomatology interventions which were identical, i.e. the sanitation of deep carries). Physiological component (sweating and voice) have been appraised by the method of clinical observation. All parameters were measured before all three stomatologic interventions. In this investigation, in parameters measured by clinical observation happened a diminution of strong small of sweating, trembling voice stammering in occasion of application of placebo therapy

Elementary mercury using as cathode in process chlorine-alkali electrolyze. Mercury vapor makes in process going in work setting atmosphere. Aim of the work is to examine whether symptoms, signs and abnormal clinical and laboratory findings are in the correlation with work in the chlorine-alkali electrolyze. Examination of air pollution work setting discovers that the major factor of air pollution is mercury vapor. On periodical view at 2000, 2002 and 2004 year was examine 571 respondent, and their diagnosis was entered in report, from which was separated symptoms, signs and abnormal clinical and laboratory findings. Workers on different workplaces are exposes in different degrees. Examinees were divided in a four group according to the grade of exposure: I group day by day exposed; II group sporadically exposed; III group earlier exposed; IV group not exposed. I, II and III group are workers which work in the process chlorine-alkali electrolyze. IV group was control group and her compose administration personal. The statistical testing differences of frequency between groups according to the grade of exposure is showed there is statistical significantly difference between I and III, and II and IV groups. We are concludes that symptoms, signs and abnormal clinical and laboratory findings, statistically significantly, there is in persons which are permanently and long term worked in the chlorine-alkali electrolyze setting, from persons which are not permanently expose or nonexpose

Klebsilla pneumoniae is the very rarely cause of osteomyelitis in adults, most commonly in the immunocompromised patients with extra-sceletal infections. Successful therapy of chronic refractory osteomyelitis included different orthopaedic methods of treatment, the long time antibiotics therapy and more and more freaquently treatment with adjuvant hyperbaric oxygenation. We report an uncommon case of patient with chronic postraumatic osteomyelitis cased by dissemination of Klebsilla pneumoniae from urinary tract to place of osteosinthesis of femur. Treatment of this case of chronic refractory Klebsilla osteomyelitis finished successfuly after treatment with hyperbaric oxygenation two years from start of desease. 

Every anesthesiologist can meet during his/her work with the patients who are suffering from rare diseases and had to be treated with surgical procedures. In a large clinical centers availability of the equipment, mentors and continual professional education are factors that are making performances of anesthesiologist's much easier. Regional hospitals, including our own one, are in much disadvantaged position. Health Center Kosovska Mitrovica is providing health treatment from the territory of Kosovo and Metohija. Due to the limited freedom of movement, these patients have to be treated "immediately and at place". Through the presentation of the case of the patient with Guillain-Barre (GBS) syndrome, we would like to underline a need for the establishment of the informational availability system through Point-of-Care Call on Line Electronic Help (OLEH) programme as it would significantly reduce the incidents related to the injuries and death cases caused by anesthesiologist procedures. Presentation of the case: Female, 42 years of age, a neurological patient with a th number of years of diagnosed illness was accepted on 13 February 2006 at the surgical department due to the abdominal pain, constipation and difficult urination. It was identified and diagnosticallv confirmed that uterus cancer spread out towards the colon, jeopardizing the bladder. It was decided that surgical procedure is reouired. Anesthesiology risk management evaluation started from the introduction with GBS. The case reviled acute inflammatory neuropathy with denivelization as the outcome of the antibodies reaction on the peripheral nerves. Chronically occurred types fas it was our easel, could lead to disruptions in breading, weakening of the muscle structure, areflection, pareses of orofaringealy physique, ophtamoplegy, chvadriplegy and chronical lung hearth. Strategy of the anesthesiological approach within the risk management procedures considered safe guidance of the patient through the pre and post anesthesioloqical period. Problem occurred was related to the limited availability of the professional literature and on-place resources related to the holistic experiences in treatment of this kind of problematic cases. The only sure available guideline was related to the avoidance of the depolarizing relaxants, which we have practiced. Within the work, we have described in details pre. peri and post anesthesiological approaches towards this problem. Conclusion: Recognition of the risk factors and multidisciplinary approach showed efficient during the peri and early post operational period. We have to indicate that development of the basic disease could have been much slower if we had assistance in respect to at-hand available and holistic information's on the rare diseases focused on the anesthesiological treatments. Therefore, it is our opinion that more qualitative system of health insurance has to introduce implementation of the hospital services standards, monitoring of the implementation and establishment of the electronic database. Developed countries such are i.e. USA, France, Italy, etc, have already introduced similar practices aimed to reduce morbidity and mortality among the patients

Falsely negative hysterosalpingographical (HSG) finding presents regular HSG finding, but the laparoscopical is pathological alterations. Falsely positive HSG findings presents pathological HSG finding, but the laparoscopical is regular finding. A high frequency of falsely negative results can be explained first of all by the presence of growths of tissue. It is known that by HSG peritubar adhesions can be suspected, but they can be diagnosed with absolute certainty only laparotomically and laparoscopically. In the period from 01.01. untill 31.12.1998. the falsely negative and falsely positive HSG findings were identified on 60 patients, which were tested by HSG method and laparoscopy. Obtained results are showed ta2 bular and graphically. Statistical data processing is carried out by Mc Nemar test (c MCN test). In the case of the HSG pathological finding, the same pathological finding has been proved in 28 (63,6%) persons, a different pathological finding in 9 (20,5%) and regular finding in 7 (15,9%). The frequency of falsely negative HSG findins is 25,0% and falsely positive HSG findings 15,9%. The frequency of falsely positive findings extends from 14,6%, 17%, 20% to 29,6%. The majority of authors state that the incidence of falsely negative findings ranges from 15,5%, 15,9%, 18%, 20,7%, 22% to 24,0%. The pathological HSG points out to the necessity of laparoscopy, while the regular HSG is not sufficient proof of normal oviducts and the peritoneal factor

Synonym Louse borne typhus represents the connection between Typhus exanthematicus and body lousiness. The results of the experiment Nicolle 1909 definitely established that. It is not explored how well the fact that Typhus is transmitted by body lice was known by doctors who were the actors of events in Serbia in 1914/15 year. A number of them categorically stated that they weren't aware of the results of Nicolla's experiments. Those honest doctors accused themselves that the fact not knowing made that “people paid by several hundreds of heads”, it was concluded that “they didn't know the theory and practice of Typhus epidemiology”. They thought that the epidemic disease would have had another direction if that had known that fact. In 1914/1 Serbia was “Typhus land stomach, recurrent and mysterious and violent Typhus”. It was the place where hypothesis “that destroying lice could be adequate proceeding in repress epidemic of Typhus” could be checked. On the epidemic culmination there was no any act or mean for effective total massive destroying lice. Disinfestations were the hygiene measure until 1915 year, and that wasn't anti epidemic measure. The working aim is to show the paradoxes: of doctors' self-accusing and confirmation on existing of special measures against Typhus. Descriptive method. Inspection in: professional, historic, fictive, accounts of its travels reviewers and archive origin on Typhus in the First World War. In 1914/15 there was no special epidemiology of Typhus. There was no effective tactic mean for massive disinfestations. Until then, nobody was stopping epidemic of Typhus bys strategy of destroying lice and their eggs. They didn't completely trusted Nicolla because current authorities believed that Typhus could be transmitted also by droplets' way. In the actual moment of epidemic culmination, the public's opinion was that disinfestations would be successful. Self-accusing of national doctors appeared after the success of English military mission. Kujachitsh was writing about Nicolla's experiments and he was a participant in war in 1914/15 and so he didn't look for a disinfestations (depediculation) mean and he didn't also strictly expressed himself on lice importance. Hirschfield, Subotitsh were looking for a mean for massive disinfestations; according to the results, they weren't successful. Scientific theory of Nicolla, and its prompt review by Kujachitsh, might be the base for positive movements, but also for tendentious “inflaming imagination” - “what could be if…”. We'll support the opinion how (the most) rationally the success could be reached: 1) what was cumulatively hypothetic by proofs becomes cumulatively confirmed; 2) supporting better stages in reaching the truth. Further appearance of sick could be added to failure: a) of tactic solution; or/and b) a strategy; or/and even solidly proved c) start, experiment of Nicolla. Interdependence is maximal first not proved conditions that the following one is problematic. There were no intention to prove that “disinfestations was successful for eradication of Typhus”, and from that appeared the failure of chosen mean, organisation of proceeding and so on, it could influence valuation of strategic result, instead of having reliable knowing on disinfestations power as a motive for finding means. The fruit of the projection and emotions is a prejudice that Nikola's theories is self-sufficient in order to make epidemic resulted in significantly less number of victims from Typhus if that had been known because all of the rest would be just result; that Stammer's mean could be easy to find. All of this produced repentance and self-accusing a number of honest doctors and that was stressed further, and it was never put under consideration although it came only after final happening. Successful tactic solution was uncertain if it was going to be found at all. Ranges of tries were not successful (Subotitsh, Hirschfield and so on). Stammer's “Serbian barrel” was enough for stopping dangerous large epidemic scale. Hunter had a planned approach to eradicate Typhus by disinfestations (depediculation), he applied that new strategic measure in the whole territory of Serbia, in: the Army, national and displaced population, as well as among the prisoners. Mostly thanking to Nicolla, only after epidemic in Serbia in 1914/15 the adequate synonym to Typhus is “Lousy Typhus”. The special epidemiology of Typhus was not constituted until 1919, and so
the valuation of not knowing the theory and practice (of special epidemiology) of Typhus was not applicable to time in 1914/15. There are no guilty ones for death of Typhus in Serbia in 1915 among the doctors. Informing that lice transmit Typhus meant that in looking for disinfestations procedure “there was no more in obligation, but more in opportunity”. Success of Stammers classifies himself among the “unusual” ones. Success of English military mission with Hunter on the top, made that Golgotha exceeded into epopee. The typhus from then always used to lose its battle.

The World Health Organization (WHO) declared tuberculosis (TB) a global emergensy in recognition of its growing importance as public health problem. In response to this situation WHO in 1990 was developed new strategy and framework for effective TB control, wich was called „DOTS“. The aims of treatment of TB are: to cure the pation of TB, to prevent death from active TB or its late effects, to prevent relapse of TB, to decrease transmission of TB to others, and to prevent
the development of acqured drug resistance. Antituberculosis drugs (ATD) are antibiotics and synthetic drugs used in the
treatment of tuberculosis and other deases caused by microorganisms of the genus Mycobacterium. The essential ATD are:
isoniazid (H), rifampicin (R), pyrazinamid (Z), streptomycin (S), ethambutol (E), and thioacetazone (T). The reserve ATD
are: amikacin (Am), kanamycin (Km), capreomycin (Cm), ciprofloxacin (Cx), ofloksacin (O), cycloserine (Cs), ethionamide (Et), protionamide (Pt), and p-aminosalycilic acid (PAS). The regimen recommended for each patient depends on the
diagnostic category for each patient. There are several possible regimens. ATB treatment regimens consists of two phases:
an initial phase and a continuation phase

Cells continuously produce free radicals and reactive oxygen species as part of metabolic processes. These free radicals are neutralized by antioxidant defense system consisting of enzymes such as catalase, superoxide dismutase, glutathione peroxidase, and numerous non-enzymatic antioxidants, including vitamins A, E and C, glutathione, ubiquinone, and flavonoids. Antioxidants include both water and lipid soluble varieties. The lipid soluble antioxidants are located in the cellular membranes and lipoproteins, whereas the water soluble antioxidants are present in the aqueous environments, such as fluids inside cells and in the blood.