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Volume 53, Issue 4, 2025

Online ISSN: 2560-3310

ISSN: 0350-8773

Volume 53 , Issue 4, (2025)

Published: 30.06.2025.

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01.12.2009.

Professional paper

SATISFACTION OF THE EMPLOYEES IN THE GENERAL PRACTICE SERVICE OF THE HEALTH CENTRE NOVI SAD

A survey was made among the employees of the Health Centre Novi Sad. It included 237 people, of which 99.6% were health workers and 0.4% administrative workers. Among the respondents 8.4% occupied a managing post. The questionnaire included the issues relating to the satisfaction of the employees with working conditions, work-associated fatigue, comparison of the job satisfaction five years ago and now, plans for the next five years, and overall job satisfaction. Based on the answers of the respondents it comes out that only 36.3% of the health workers are satisfied and very satisfied with their jobs, which is a very small percentage regarding the nature of the work they do. However, 42.2% of health workers plan to remain in the public sector in the next five years, and 41.8% do not even think about changing the job. This was logical to expect bearing in mind the material position of the health care and overall economic situation in the society. 

M. Vojnović, R. Doder, M. Ban, J. Kolarović

01.12.2009.

Professional paper

ÎPERATIVE TREATMENT OF PREMALIGNANT AND MALIGNANT CHANGES ON CERVIX UTERI AT GYNECOLOGY & OBSTETRICS CLINIC OF CLINICAL CENTER OF MONTENEGRO IN THE PERIOD OF 1999-2008

Cervix cancer is the second most frequently found cancer in women, after breast cancer and represent one of the biggest problems of modern medicine. The aim of treatment is to determine the frequency of certain premalignant and malignant changes in cervix and the method of its operative treatment. By a retrospective method, 360 women have been operated due to the changes in cervix from 1999-2008 at Obstetrics &Gynecology Clinic of Clinical Center of Montenegro. Out of this number the total of 297 women with premalignant lesions of cervix was found and 63 women at an operable stage of cancer. With premalignant cervix changes the most frequent indication for operation was CIN III - 24.57% of patients. Cervix conization -80.13% is most frequently used as an operable intervention with premalignant changes in cervix. The groups of 40-49 years of age and 50-59 years of age are the ages of patients with most frequently conization done. The most frequent indication to operate malignant cervix was Ca I b. Wertheim-Meigs radical hysterectomy was performed with all patients with operable malignant changes. With an early identification, an adequate evaluation, the treatment, constant and cautious monitoring, almost any cervical intraepithelial neoplasia can be cured. Without the treatment, 30-50% of cervical dysplasia can advance into and invasive cervix cancer. 

A. Boljević, G. Globarević-Vukčević, S. Raičević, M. Jovanović, D. Kljakić

01.12.2009.

Professional paper

VIRAL HEPATITIS A IN MUNICIPALITY OF PRIJEDOR

Acute viral hepatitis A (HAV) is a benign self-limited disease, which does not become chronical and does not require obligatory hospitalization. It's an intestinal infectious disease with a dominantly fecal-oral way of transmission. Endemic epidemic appearance of this disease on the municipality of Prijedor, with a very high level of incidence, from the sixties of the 20-th century, has put the viral hepatitis among the priority problems of epidemiologic practice. During the period 1965-2007. in Prijedor there were 5707 registered cases of HAV contaminated people and three death cases. From 1990 it has been noticed an epidemiologic regression of HAV followed by its complete absence during the period 1997-2007. Studies of reasons of HAV regression have been conducted by a descriptive-epidemiologic method according to sex, age, ethnic affiliation, place of residence, seasonal appearance of disease, and the way of water supply. It has been determined that there is no statistically important differences among contaminated people according to sex, differences in other treated parameters correspond to the data from literature [1,2]. Seroconversion has been proved in 53 persons or 55,2% of tested people. Percentage of sero-positive people was 93,7% among people older than 60 years of age and 79,2% among the refugee population. Based on studies, the epidemiologic regression of HAV from the 90-ties of the 20th century, is explained by the fact that this disease appears in the interepidemic period, that there is a significant collective immunity of population with the HA virus, and the most important, the basic epidemiologic factors which contribute to the spreading of disease have been removed - the majority of population live in the urban and suburban areas where a hygienic water supply has been provided for. Also the customs and habits of population have been significantly changed. 

D. Anðelković

01.12.2009.

Professional paper

ORGANOPHOSPHOROUS INSECTICIDE POISONING - EMERGENCY TREATMENTS IN THE CLINIC HOSPITAL - BITOLA

Organophosphates are famous insecticides which are often used as suicide venoms in Bitola's surrounding. When treating such patients you should gastric washing, keep the airways clear, give Atropin until fully atropinized, give symptomatic therapy. All patients need to be hospitalized. The treatment for this kind of patients is finalized with a psichyatric observation.

V. Radivojević, S. Radivojević

01.12.2009.

Professional reviews

PHYSICAL-TECHNICAL PRINCIPLES OF COMPUTERIZED TOMOGRAPHY

Theoretical principle of computerized tomography was set by Czech mathematician J. Radon in 1917.The development of computerized tomography is connected with the name of A.M Cormack who, in 1963, started with the research directed at X-ray beam intensity measurement after passing through certain substance.First computerized tomography appartus was installed in Atkinson-Morley hospital in October in 1971 in London. Computerized tomography is based on making transverse(axial) cross-section of body parts,by X-ray beam passing through visible body part and by measurement of X-ray absorption degree using detectors. A cross-section picture of certain body part is obtained on a monitor as a final result of CT examination. A system of picture digitalisation and application of grey scale concept is particularly complex. Basic elements of CT are gentry, patient's bed, high-voltage generator, working and computer console, system for transferring picture on a film or other electronic media. Densimetric tissue values can be measured on the obtained CT picture. A change can be isodense, hypodense or hyperdense. Density change is expressed in Hounsfield units. Contrasting remedies can be applied, during CT, intracanalicular or intravenous. A better quality survey of changes increasing tissue density is obtained using them. CT application is indicated in diseases such as:neurocranium, visceral cranium, spinal column, thorax, abdomen, skeletal, joint and muscular system. X-ray side effects and precaution risks are being described in the text.

T. Jovanović

01.12.2009.

Professional reviews

ADIPOKINES AS FOR RUNNERS OF INFLAMMATORY CITOKINE SUPERFAMILY AND ITS INVOLVEMENT IN INFLAMMATORY AND IMMUNE DISEASES

Leptin was discovered in 1994, finding, that marked the beginning of a new understanding about white adipose tissue. Up to end of 20th century this tissue was viewed as an inert tissue, devoted to body protection from heat loss and to passively store energy. This static vision, changed with identification of the product of the gene obese (ob) wich accentuated the role of adipose tissue in the physiopathology of obesity-linked diseases, and led to the discovery of various adipokines, many of a pro-inflammatory nature. With emerged knowledge of (WAT)-derived adipokines, it is obvious that they can be now considered as the bond between obesity-related environmental causes, such as nutrition and lifestyle, and the biochemical shifts that lead to metabolic syndrome, inflammatory and/or autoimmune conditions, and rheumatic diseases. This paper deals with reviews of recent adipokine research, with particular emphasis to the role of leptin, adiponectin, resistin, and visfatin in chondrocyte function and skeleton, as well as in inflammatory and degenerative cartilage joint diseases.

Lj. Smiljić, M. Radunović, M. Muratović, T. Smilić

01.12.2009.

Professional paper

FREQUENCY AND COMPLICATIONS ANGIOEDEMA QUINCKE AMONG HOSPITALIZED PATIENTS

Introduction: Approximately 15-23% of the general population have had urticarial rush during their lives. Goal: Examination of the urticarial frequency and urticarial etiopathogenesis among hospitalized patients. Sources and methodology: Retrospective analysis of the data extracted from patients' medical history at the Clinical Center of Kragujevac, Department for Dermatology and Venereology. Statistical methods used include proportional relations with tabular and graphical representation of the results gathered. Results: Out of 228 hospitalized patients in 2007, total of 28 (or 12.28%) were treated for Urticaria. The disease is more frequent among the following groups of patients: female population (total of 23, or 82.1%); people between 30 and 60 years of age (total of 15, or 53.6%); urban area population (total of 24, or 85.7%); patients with Dg. Urticaria acuta diagnosis (total of 19, or 67.8%); Dg. Oedema Quincke (total of 6, or 21, 4%); et people with cardiovascular diseases (total of 9, or 32.2%). The disease is more frequent in Spring, during the period April-June (11 patients, or 39.3%) with the greatest frequency in May (7 patients, or 25%). According to etiological samples the most prominent types of Urticaria among patients were: idiopathic (13 patients, or 46.4%), due to medications (5 patients, or 17.9%), nutritional origin (4 patients, or 14.3%), psychological factors (3 patients, or 10.7%). Considering complications, 6 patients (21.4%) had Quincke's Oedema, while 7 patients (25%) had allergic reactions to penicillin. Regarding outcome of the disease, total of 23 patients (82.1%) have been successfully cured. Discussion et Conclusion: The greatest number of serious urticarias with complications has been inducted by non-physical factors, mostly of immunological nature, while physically inducted urticaria have had less severe symptoms and required shorter time to cure. Nevertheless, exact causes for most types of urticaria are unknown, so continual research of causes, as well as courses, complications and treatments of this serious disease is necessary.

N. Krstić, M. Relić, B. Belić, R. Stolić, S. Sovtić, T. Novaković

01.12.2009.

Original scientific paper

THE STATE OF HEALTH OF CHILDREN IN SERBIAN ENCLAVES IN KOSOVSKO POMORAVLJE (2008/2009 SCHOOL YEARS)

In 2008. 1402 children of 1st,3rd,5th and 7th grade of 18 elementary schools in Serbian enclave of Kosovo Pomoravlje, were examined. This are villages of municipality of Gnjilane, Vitina, Novo Brdo and Kosovska Kamenica. I general 2816 children attend the elementary school. 932 of all examined children had a deformity, every ten had kyphosis, and every 8-10 had scoliosis. Every 5th child of 1st grade and every 6th child of 3rd grade had anemia. Some kind of flat-footed (pedes pllani) had every fifth to every third child. Only every tenth child was fat. 

Z. Dimeski, J. Živković, S. Milutinović, M. Milanović

01.12.2009.

Professional paper

AN ASSESSMENT OF INCOMPLETE EXCISION OF SKIN CANCER - IMPACT OF ASSOCIATED FACTORS

Skin cancer is the most common form of human cancer. The annual rates of all forms of skin cancer are increasing each year, representing a growing public health problem. The two most common form of skin cancer are basal cell and squamous cell carcinoma, well known as nonmelanoma skin cancer. Treatment of nonmelanoma skin cancer depends on the type and location of the skin cancer as well as the age and general health of the patient. Surgical excision is the most common metod in the treatment of basal and squamous cell carcinoma. One of disadvantages of simple surgical excision is incomplete margin control. The aim of this prospective study was to assess the influence of the size of the tumor and intraoperative surgical margin on the rate of complete excisions of skin cancer. A total of 64 basal cell and squamous cell carcinomas were excised and analyzed. Data pertaining to patient age, sex, lesion size and margin of excision were collected prospectively. After excision, all tumors specimens were histopathology confirmed completeness/ incompleteness of tumor excision. Tumor size ranged from 5mm to 36mm. Surgical margins were used in the range of 5-12mm. Skvamocelularni carcinomas were incompletely removed in 4.2%, and basal cell carcinomas in 10% of cases within the histopathological groups. Basal cell carcinomas: surgical margin of 5 mm radically removed 83.3% (up to 1cm); 8mm margin- 86.7% (1-2cm): and 10mm 100% (over 3cm). Squamous cell carcinomas: 10mm surgical margin removed 100% tumors up to 3cm.

G. Videnović, G. Bjelogrlić, V. Stojanović-Kamberović

01.12.2009.

Professional paper

THE MOST COMMON PATHOGENS OF BACTERIEMIA AND THEIR RESISTANCE IN HOSPITALIZED PATIENTS

To show the most common causes of bacteriemia in hospitalized patients, as well as their sensitivity to antimicrobial agents. The research data were extracted from official reports produced by Microbiological Laboratory in Clinical Centre Kragujevac. Isolation and identification of the causes were performed with standard microbiological methodology. Sensitivity to antimicrobial medication was tested using disc diffusion. Interpretation and inhibition zones of antibiogram were done in accordance with guidelines of US Clinical and Laboratory Standards Institute (CLSI). A descriptive epidemiological approach was used in the research. The collected data were processed using the appropriate software application. Amongst the processed samples, a significant presence of Staphylococcus spp. was found (coagulase-negative 35,8% and coagulase positive 11,7%). Over 60% of Staphylococcus aureus isolates were resistant to meticillin. Enterococcus spp, isolated in 11,7% of all isolates, in more than 50% of cases was sensitive to ampicillin, with approximate isolate vancomycin sensitivity of 90%. The isolated Klebsiellà spp strains produced high degrees of Extended-Spectrum â-Lactamases (ESBL) and showed resistance to third-generation cephalosporins, aminoglycosides and ciprofloxacin, with 100% sensitivity to carbapenem. Pseudomonas spp and Acinetobacter spp were less represented (5.8% and 5.4%) but these neither pathogens were exempt to antimicrobial resistance.The research indicated that causes of hospital infections should be continuously monitored. 

Z. Đorđević, S. Milinić, R. Stolić, N. Đonović

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