Akne vulgaris su hronično inflamatorno obolenje pilosebacealne jedinice. Dermatološka obolenja često su asocirana sa psihološkim problemima koje ima pacijent. Psihodermatološke bolesti (akne) su asocirani sa kožnim simptomima koje nisu direktno povezani sa psihom, ali reaguju na emocionalne situacije,kako što je stres. Cilj ovog rada je da se utvrdi da li postoje određene psihološke karakteristike, koje su zajedničke za čitavu grupu obolelih, i da li postoji korelacija između težine kliničke slike i psiholoških parametara. Naše istraživanje je obuhvatilo 30 pacijenata sa tri klinička oblika akni.Za identifikaciju i dijagnostiku psihičkih poremećaja korišćen je test ličnosti Kornel-index. Zastupleni rezultati su neurastenični parametri, parametri konverzije i parametri psihopatije u različitom procentu kod oba pola i različite kliničke slike. Dobili smo pokazatelje za grupisanje više jednovremenih nalaza. Pokazali smo korelaciju udruženih 2-6 psihosomatskih poremećaja kod muškog pola sa lakšim oblikom akni. Kod ženskog pola sa bilo kojim oblikom akni, odgovorni su bili 7-12 udruženih nalaz. Udruženost više psihosomatskih faktora može da bude odgovorna za pojavu bilo kog oblika acne vulgaris

Human preterm labor is a syndrome that may arise from different causes. Before 30 weeks of gestation, infection appears to predominate amongst these. In later gestation, premature activation of the fetal HPA axis in response to an adverse intrauterine environment, e.g. hypoxemia, undernutrition (UN) or even infection, may underlie the stimulus to prematurity. A third pathway clearly involves vascular thrombotic processes. Tests on sheep have been shown to there is a premature birth which is a significant change was associated with precocious increases in adrenocorticotrophic hormone (ACTH) and cortisol in the fetal circulation, and increased levels of mRNA encoding proopiomelanocortin (POMC) and prohormone convertase-1 (PC-1) in the pars intermedia of the fetal pituitary. It would seem that these different pathways may occur separately, or be activated to different degrees in the same patient.

 Atrial arrhythmias are an often and common problem in patients with arterial hypertension. Some recent studies have shown that the electrical pulse delay estimated by echocardiography is prolonged in patients with paroxysmal atrial fibrillation compared to healthy persons. To assess the electromechanical function of the left atrium in patients with various degrees of hypertension compared to healthy persons. The study has included 103 patients with artery hypertension, who were divided into four groups according to the degree of arterial hypertension and 46 healthy persons as a control. The volumes of the left atrium were measured by echocardiography using the disk, active and passive emptying volumes of left atrium and the fractions were calculated. Electrical delay within the left atrium and between the two atria were measured using the tissue Doppler. The values of passive left atrial emptying fraction were highest in patients in the control group and in patients with prehypertension they have significantly declined with the increased degree of hypertension (12.8 vs 12.6 vs 11.2 vs .10.2 vs 9.9%, p˂0.001). The values of the active emptying fractions left atrium were higher in patients in the control group and with prehypertension threy have significantly declined as increased degree of arterial hypertension (28 vs 23 vs 40 vs 40 vs 39%). Electrical delay within the left atrium was significantly lower in patients in the control group and it has been significantly increased as a growing belonging to a group with higher levels of arterial hypertension (6 ... 9 ... 15 ... 23 ... 31 ms, p˂0.001). Patients with prehypertension had significantly higher values of electrical delays within the left atrium compared to the patients in the control group. Electrical delay between the two atria grew significantly as a growing belonging to the group with a higher degree of hypertension (15.6 ... 25.3 ... 35.2 ... 50.2 ... 67.4ms, p˂0.001). The study showed that even patients with regulated arterial hypertension have disturbed electromechanical function of the left atrium. Electrical delay in the atrium between the two atria is extended to the increasing degree of arterial hypertension, which can be explained by the higher risk for atrial arrhythmias in these patients.

Twin to twin transfusion sindrom (TTTTS) je patološko stanje gde blizanac donor „krvari“ u cirkulaciju fetusa recipijenta preko abnormalnih interblizanačkim placentnih anastomoza. Blizanac donor postaje anemičan, hipovolemičan, zaostaje u rastu i kao posledicu ima smanjenu urinarnu produkciju. Kako funkcija gutanja amnionske tečnosti nije oštećena, volumen plodove vode se progresivno smanjuje. Blizanac recipijent postaje hipervolemičan i policitemičan. Višak cirkulišuće krvi i nemogućnost adekvatne eliminacije nekada može da dovede do pojave hidropsa u težim slučajevima. Povećana urinarna produkcija recipijenta vodi pojavi polihidroamniona i prekomernoj distenziji amnionskog kavuma, kompresije i smanjnje perfuzije donora. Redukcija amnionske tečnosti kod donora rezultuje fiksacijom donora uz zid uterusa (najčešće prednji zid), (Slika 1.) (stanje nazvano stuck twin) 1,36.

Pokušaj samoubistva predstavlja aktivnosti koje imaju za cilj oduzimanje sopstvenog života, a koje ne završavaju smrću. Odnos pokušanih i realizovanih samoubistava izražen je tzv. Indeksom opasnosti (Hazard ratio). Faktori rizika koji podstiču samoubilačko ponašanje su: različita emocionalna stanja, crte ličnosti, stresogeni životni događaji, zloupotreba psihoaktivnih supstanci itd. Cilj rada: prikazati učestalost i epidemiološko demografske karakteristike pokušanih samoubistava kod žena i muškaraca. Urađeno je istraživanje na uzorku od 56 pacijenata kod kojih je postavljena dijagnoza pokušaja samoubistva (Tentamen suicidii), na psihijatrijskom odeljenju KBC Priština, Gračanica. Uzorak je analiziran na osnovu pola, starosne dobi, zanimanja/zaposlenosti, psihijatrijske dijagnoze, motiva i načina pokušaja samoubistva. Rezultati: samoubistvo su pokušale 42 žene (75%) i 14 muškaraca (25%). Najveći broj ispitanika (26.8) u našem istraživanju su iz starosne dobi <20 godina. Najzastupljeniji su nezaposleni, 33,3% žena i 50% muškaraca. Najčešća dijagnoza su anksiozni poremećaji, 61,9% žena i 57,1% muškaraca. Najčešći motiv kod žena je patrnerski konflikt 54,8%, kod muškaraca egzistencijalna ugroženost 50%. Od 56 pacijenata njih 51 (91,1%) je pokušalo samoubistvo trovanjem i to anksioliticima. Znatno veći broj pokušaja samoubistva (75%) desio se u popodnevnim i vešernjim časovima, u periodu od 12 do 24h. Zaključak: žene su češće pokušavale samoubistvo u odnosu na muškarce, odnos 3:1. Najčešće nezaposleni kod oba pola ispitanika, najčešća dijagnoza, anksiozni poremećaji. Najzastupljeniji motiv kod žena je partnerski konflikt, kod muškaraca egzistencijalna ugroženost. Kod oba pola ispitanika najčešći način pokušaja samoubistva je trovanje, najčešće u periodu od 12 do 24h.

Post-streptococcal glomerulonephritis (PSGN) is a frequent cause of acute nephritis in children. This case study was done with the aim to point out that the infections caused by Group A streptococci, in spite of antibiotic era, are still present in the population. An 8-year old boy was admitted in our hospital with a two-day history of fewer, tonsillopharyngitis. After hospital admission, patient was treated with penicillin during the period of 10 days, antihypertensive medications (captopril, furosemide), including restricted diet of salt. After the treatment, patient became better. On demission it was found proteinuria and microhematuriaPSGN is very serious disease, which leaves severe complications if the valid therapy with penicillin is not used in propriety time, during the recommended period of 10 days.

Preterm premature rupture of membranes (PPROM) is in obstetrics with incidence of 0,4% of , with risk for chorioamnionitis 35%, risk for premature deli very 19%, and sepsis risk of 1%. Primary risk for fetus is pulmonal hypoplasia due to oligohydramnios in 29%, RDS in 66 % of such pregnancies, sepsis in 19%, and contrac ture of extremities in 3%. Fetal death is more than 30% of cases. Patient came to regular pregnancy check up in 22th week of gestation. US exami nation revealed decreased fluid volume AFI 50, with regular morphology and fetal dynamic. She was admitted to hospital. She was given cortico-steroids and antibiotics. In further course of pregnancy amniocentesis was performed in 32th week of preg nancy to rule out the infection and to check pulmonal maturity. In absence of infection and lung maturity pregnancy was continued until 36th week of gestation when Cesarean Section was. Baby went well and is now healthy child in the age of three. Some studies suggested that delivery can be significantly prolonged. In our case we menaged to gain 14 weeks,from 22th to 36th gestational week. Firstly gynaecologyst nightmare to ask the woman is she accept therapy. The aim is to deliver a healthy child without neurological and other consequen ces and mother with preserved reproductive function. Controversy still exists when is the appropriate time to finish pregnancy with prolonged PPROM.

Transposition veins, in some cases when there is no adequate superficial veins, preferred is model of the vascular access. This approach may be acceptable version vascular access where is not possible to create other shapes. But basilic vein transposition is time consuming and technically challenging procedure with significant perioperative morbidity. Complication rate for basilic vein transposition remains high at 47-71%. We report a patient who underwent transposition basilic vein, and its anastomosis with radial artery, in which developed the digital hypoperfusion ischemic syndrome.

Prognoza i izbor terapije adenokarcinoma prostate (ADKP) direktno zavise od brojnih prediktivnih faktora, među kojima su najznačajniji zbirni histološki gradus tumora (Gleason score, koji predstavlja zbir prvog i drugog dominantnog histološkog gradusa) i klinički stadijum. Novija istraživanja u ove faktore ubrajaju i tkivni androgen status i neuroendokrinu diferencijaciju. Važnost prvog i drugog dominantnog histološkog gradusa naročito postaje značajan kod ADKP Gleason score-a 7. Smatra se da goru prognozu imaju ADKP višeg Gleason score-a, uznapredovalog kliničkog stadijuma, androgen nezavisni tumori i tumori koji pokazuju veći stepen neuroendokrine diferencijacije. Cilj rada je odrediti prediktivni značaj ADKP Gleason score-a 7 (3+4) i ADKP Gleason score-a 7 (4+3) u odnosu na klinički stadijum, tkivni androgen status i stepen fokalne neuroendokrine diferencijacije. Istraživanje je obuhvatilo 33 ADKP Gleason score-a 7, odnosno 26 (78,79%) ADKP 7 (3+4) i 7 (21,21%) ADKP 7 (4+3). Svi tumori su najčešće dijagnostikovani u stadijumu D2 kada su već postojale udaljene metastaze. ADKP Gleason score-a 7 (4+3) dijagnostikovani su u većem procentu u ovom stadijumu, među njima ima više androgen nezavisnih tumora i pokazuju veći stepen fokalne neuroendokrine diferencijacije. Svi dobijeni rezultati u saglasnosti su sa podacima iz literature i navode na zaključak da ADKP Gleason score-a 7 (4+3) imaju goru prognozu od ADKP Gleason score-a 7 (3+4).

Postoje brojni faktori koji mogu da utiču na kraniofacijalnu morfologiju, prvenstveno genetski faktori i faktori spoljne sredine. Cilj ove studije je da se na onovu podataka dobijenih pregledom školske dece dobije približniji opis kraniofacijalne morfologije na ovoj teritoriji. Istraživanjem je bilo obuhvaćeno 330 dece starosti od 8 do 11 godina. Za ovu studiju koristili smo standardne antropometrijske metode za merenje širine i visine lica, širine i dužine lobanje i izračunavanje indeksa lobanje i lica. Dobijeni rezultati su statistički obrađeni a Z skorom izračunat indeks kraniofacijalne varijabilnosti (CVI). On na numerički način opisuje varijabilnost kraniofacijalne morfologije i postojanje slučajeva izvan opsega ovog indeksa. Prema prosečnim vrednostima indeksa lica dečaci i devojčice u gotovo svim ispitivanim godištima pripadaju kategoriji mezoprozopa (47.4%). Analize indeksa lobanje kod dečaka i devojčica govori da su najcesce zastupljeni brahiokefali (52.2%), zatim mezokefali (43.5%) i dolihokefali (4.3%).