Fibroepithelial polyps of the vulva are specific mesenchymal lesions that are commonly found in the vulvovaginal region in reproductive period and in premenopausal females. We present a case of a 36 year old female, who came for examination because of interruption of unwanted pregnancy. During the examination we revealed a large flank mass on the stalk, which started from the right labia. Tumor formation was measuring 165x120x10mm, soft consistency, painfully insensitive to palpation. The tumor was removed by excision, cutting the stem at the base and the material was sent for histopathological examination. Histopathological findings confirmed that this is a fibroepithelial polyp of the vulva.

Parodontopathy is a complex disease of periodontal tissues. The patological changes that occure here are destructive and lead to gradual or progressive periodontium disease and its anatomical and functional desintegration. The aim of the research was to use the PCR method (Polimerase Chain Reaction) to identify the presence and spreading of the oral pathogen Actinobacillus actinomycetemcomitans in subgingival plaque in patients suffering from the agressive parodontopathy and then compare it to qualitative-quantitaive structure of dental plaque in patients suffering from chronic parodontopathy. The study included 70 patients, average age of 45. The identification of microorganisms in subgingival plaque was determined by PCR method. In order to comfirm the diagnosis and determine the extent of destruction of periodontal tissue the standar epidemiological criteria were used: plaque index (Silness-Lӧe), gingival index (Lӧe-Silness), SBI index (Mühleman-Son) and DPP. Extremely high statictical significance of presence of A. actinomycetemcomitans was obtained in patients with agressive parodontopathy. The presence of A. actinomycetemcomitans and P. gingivalis showed the difference in distribution in patients with chronic as well as in patients with agressive pardontopathy. In our sample A.a was detected in a high percentage of younger patients with the diagnosis of agressive parodontopathy. Higher rate of A. actinomycetemcomitans in subgingival plaque has a direct impact on the course of parodontopathy. Its detection may be a useful marker for identifying the icreased risk for developing agressive parodontopathy in patients of younger population.

Anatomy of the female pelvic viscera was investigated before and after the Tension free Vaginal tape (TVT-O). Forty patients were included in the study. Surgery was performed between 2009 and 2012 in Clinic of Urology (Clinical Center Nis) and Department of Urology (Municipal Hospital Prokuplje). Stress Urinary Incontinence (SUI) and anterior vaginal wall prolapse was confirmed in all patients. In all patients with anterior vaginal wall prolapse (grade≥2) both tension free vaginal tape (TVT-O) and anterior vaginal wall repair were performed. Pelvic Organ Prolapse Quantification (POPQ) system was used for the evaluation of prolapse before and after the surgery. Mean age of patients was 61 years. Spinal anesthesia was performed in thirty patients and general anesthesia in 10 patients. Intraoperative blood loss was under 50 ml. There were no bladder, nerve and blood vessels injuries . Thirty eight out of forty patients (95%) were satisfied with the outcome of the surgery. There was a significant correction of prolapse after the surgery. Recurrence of prolapse was found in patients with the high grade prolapse before the surgery, as well as, in patients with the history of previous anterior vaginal repair. Pelvic organ prolapse, congenital or acquired, is supported by the congenital weakness of the pelvic floor.

In care of minimal partial edentulism, ie the lack of a tooth, as an alternative method can be used inlay retained adhesive restorations. The aim of this paper is to present possibilities for the application ceramic systems used for adhesive prosthetic restorations. In the making inlay restorations in the region of the posterior teeth can be applied ceramic system of higher strength which can be veneered with translucent ceramics. With the development of adhesive dentistry, it is possible to establish a strong link between restoration and teeth by means of composite cements and thus ensure sustainability of recovery. The clinical procedure is simple, minimally invasive, and provides a glimpse into a way of making inlay retained fixed restorations.

Tests have shown that adipose tissue is very important in the production of chemical substances that have a major impact on atherosclerosis. The basic fat cells adiposity is very active in bio secretion hormones and other substances. Adiposities secrete chemical substances such as leptin, resistin, adiponectin, and others who participate in metabolic processes. One of the most important adipocytokine affecting the formation and the regression of atheromas plaque in the coronary blood vessels are adiponectin and resistin. So our aim was to determine the value of the concentration of adiponectin and resistin on patient with myocardial heart attack and determine their correlation with the control group of healthy subjects. In this study were included 68 subjects, 40 with myocardial heart attacks and 28 control groups of normal healthy. In the group with myocardial 78.6% of respondents were male and 21.4% female. Tests have shown that the concentration of adiponectin in the group with myocardial heart attack was significantly lower than the control group (4.94 to 6.74, p=0.043, p<0.05. In the same study group average value of resistin was significantly higher than in the control group (15.73 to 7.88, p=0.001, p<0.01) (Student's t-test, p = 0.581, p> 0.05). All this indicates that in patients with myocardial heart attack there is a decline in the concentration of adiponectin, which has cardio protective effect. The increase in resistin in myocardial heart attack in directly related to the appearance of athermanous plaques in the coronary blood vessels and has a bad prognostic significance.

Introduction: The study of importance of left ventricular contractile reserve presence and changes plasma brain natriuretic peptide levels (BNP) during exercise in patinets with idiopathic dilated cardiomyopathy is very popular today, but these two parametres have rarely been interconnected. The study of response BNP during echocardiography stress tests in patients with idiopathic dilated cardiomyopathy with or without preserved left ventricular contractile reserve. We studied 55 consecutive patients with idiopathic dilated cardiomyopathy (mean age 54.98 ± 9.84, 49 (89.1%) male) treated in the outpatient clinic for heart failure at the Institute of Cardiovascular Diseases "Dedinje". All the patients underwent the echocardiography stress test. Contractile reserve was assessed by measuring of the changes of the left ventricle ejection fraction basally and in the first minute after the strongest stress. Level of BPN was measured at rest, in the first minute and after 20 minutes of maximal exercise stress. Following the kinetics of BNP level during stress testing, we find that in patients with preserved left ventricular contractile reserve BNP level is rising at maximum load achieved (Mediana (IQR) - 59 (22-113) vs. 91 (37-135) vs. 78 (30-159) ng/L, p<0.001), whereas in patients without preserved left ventricular contractile reserve BNP level does not change significantly (Mediana (IQR) – 89 (50-322) vs. 119.5 (61.3-321.8) vs. 136 (72- 281), p=0.102). The increase in BNP in the peak load compared to its value at rest was positively correlated with preserved contractile reserve (r=0.38, p=0.009), better WMSI at rest (r=-0.28, p=0.04), greater difference in the double product (r=0.40, p=0.002), as well as the work accomplished on the test (r = 0.47, p <0.001), and longer duration of the test (r = 0.43, p = 0.001). The increase in BNP during physical exercise in patients with idiopathic dilated cardiomyopathy suggests a preserved contractile reserve of the left ventricle.

Savremeni akcenti u tretmanu varikocele. Postići “minimalnu invazivnost” tretmana, odrediti broj trudnoća nakon operacije i ustanoviti vremenski period od operatvnog zahvata do začeća kod partnerki. Selektovana grupa muškaraca pomoću uroloških kriterijuma za infertilni par, tretiranih subingvinalnom ligaturom spermatične venepampiniformnog pleksusa. Tretirali smo 26 subfertilnih muškaraca kombinacijom subingvinalne ligature spermatične vene ili pampiniformnog pleksusa i medikalmentozne terapije.U desetogodišnjem periodu, registrovali smo 16 trudnoća (61,5%) partnerki naših pacijenata. Smatramo da je subingvinalna ligatura spermatične vene minimalno invazivan i isplativ početni tretman “infertilnih parova”.

Maligni tumori pljuvačnih žlezda su retka oboljenja i u najvećem broju se javljaju u velikim pljuvačnim žlezdama. Cilj istraživanja bio je da se analizira trend incidencije malignih tumora velikih pljuvačnih žlezda kod stanovništva grada Beograda. Podaci su dobijeni iz Registra za maligne tumore centralne Srbije. Analizirani su svi slučajevi malignih tumora velikih pljuvačnih žlezda registrovani u Beogradu od 01. januara 1999. godine do 31. decembra 2010. godine. Trend kretanja i godišnji procenat promene incidencije izračunat je regresionom analizom uz pomoć tačaka spajanja (engl. joinpoint regression analysis). U ispitivanom periodu Registru je prijavljeno je 283 pacijenta (168 muškaraca i 115 žena) sa malignim tumorima velikih pljuvačnih žlezda. Standardizovana stopa incidencije svih tumora u ispitivanom periodu, za oba pola, bila je 0,87/100,000 stanovnika, odnosno 1,13 za muškarace i 0,67 za žene. Standardizovana stopa incidence se uvećavala sa godišnjim procentom promene od 6,4% kod oba pola (p<0,001). Rezultati su pokazali konstantno povećanje trenda incidencije malignih tumora velikih pljuvačnih žlezda kod stanovništva grada Beogradu između 1999. i 2010. godine.