Najčešći nemelanomski maligni tumori kože epidermnog porekla su bazocelularni (BCK) i planocelularni ili spinocelularni (PCK) kože. Nastaju na fotoeksponiranim delovima kože i u 90% slučajeva su povezani sa oštećenjima kože nastalim dugotrajnom izlaganju UV zracima, kod osoba svetle puti i strarijeg životnog doba. Cilj ovog rada bio je ispitivanje kliničko morfoloških i histopatoloških karakteristika obe vrste nemelanomskih karcinoma kože i prekanceroznih promena na koži. Urađena je jednogodišnja epidemiološka analiza najznačajnijih parametara. Od ukupno 50 pacijenata PCK je dijagnostikovan kod 46%, BCK kod (32%), i prekanceroze kod 22%. PCK je češći kod muškaraca 52,8%. Prekanceroze lezije prisutne su kod oba pola podjednako. Muški pol je predominatan za nemelanomske karcinome kože .Od ukupnog broja 72% je muškog pola. Prosečna životna dob kod oba pola iznosi 67.22. Najmlađa osoba imala je 41. godinu dok je najstariji pacijent imao 93 godina. Lice je najčešće zahvaćena regija sa 73,9%. Najučestaliji histološki gradus za PCK je gradus I (60,9%) Interesantno je da je PCK kod žena najčešće bio lokalizovan na leđima 28,6% dok kod muškaraca nismo imali ni jedan slučaj lokalizacije na leđima. Mešovita (43,8%) i nodularna forma(37,5%) su najučestalije u grupi BCK-kože dok je superficijalna tek na trećem mestu(18,8%). Zapaljenski eksudat mononuklearnog tipa bio je prisutan kod svih oblika NMTK i to kao umeren (72%) i izražen(28%). Uspešnost hirurške ekcizije merila se pozitivnim linijama resekcije koje su kod BCK bile kod tri pacijenta(6%)a kod PCK u 6 pacijenata (12%).

Introduction: Hypersensitivity pneumonitis is a complex pulmonary syndrome mediated by the immune system and caused by inhalation of antigens to which the patient has been previously sensitized. From the clinical point of view hypersensitivity pneumonitis can be divided into acute/subacute, and chronic phenotypes. It is characterized by an insidious onset of cough, dyspnea, fatigue, and weight loss that develop over several weeks to a few months. Case report: A 52-year-old patient came in February 2017 with high temperature, chest tightness, dyspnea, persistent cough, hemoptysis and weight loss of more than 6 kilograms. Radiography and computerized tomography showed poorly defined small diffuse centrilobular bilateral nodules. Inspiratory crackles were detected by physical examination. Routine laboratory tests were regular. Bronchoalveolar lavage fluid analysis and lung biopsies by video-assisted thoracoscopic surgery indicated the presence of diffuse lymphocytic infiltrates and giant cells with non-necrotizing granulomas and cellular bronchiolitis. Hypersensitivity pneumonitis diagnosed. She was given 35 mg deflazacort, bronchodilators to widen the airways and etamsilat pills. We did not identify the causative agents, including home, workplace and recreational environmental factors.Conclusion: Making the correct diagnosis has critical therapeutic and prognostic implications. Patients with hypersensitivity pneumonitis should be referred to expert centers, as the overlap with other forms of interstitial lung disease may be deceiving. The mainstay in managing this illness is to avoid the causative antigen, though complete removal is not always possible.

INTRODUCTION: Stress at work is a major problem in the modern world in many areas of work, especially in health care. Occupational burnout of nurses represents a serious problem, not only for themselves. It also affects the quality of the health services provided to patients. OBJECTIVE is to examine the connection between occupational stress and occupational burnout among nurses working in public health institutions. METHODS: An examination was carried out to determine aconnection between occupational burnout and occupational stress among nurses working in the hospital, at the departments of surgery, gynecology and emergency. For the evaluation of professional burnout among nurses, the Maslach Burnout Inventory, MBI-HSS pattern, was used, and Matteson and Ivancevich Questionnaire was used to assess occupational stress. Statistical data processing was done by the SPSS 17 software.RESULTS A total of 60 examinees were included in the study, 20 of them from the Surgery, Gynecology and Emergency department. Of these, 51 (81.7%) arefemale and 9 (18.3%) are male. The average age of nurses is 41.45 years, from which 40.9on Surgery; 41.8 on Emergency; 41.65 on Gynecology, and the average years of serviceare 17.91. Descriptive statistics for the examined variables are shown and it can be seen that there is a low level of occupational stress, i.e. the result is below 21.In the occupational burnout variable, respondents show the medium level of emotional exhaustion (M=24.05), low level depersonalization (M=3.83) and low level of lack of professional achievement subscale (M=38.71). The test results confirm the first hypothesis (H1) that with the increaseof occupational stress levels, the level of occupational burnout among nurses also increases.Occupational stress correlates with occupational burnout (r=0.529, p<0.01), i.e. nurses who have higher results of occupational stress, have more occupational burnout results also. The results of the tests involving correlations between occupational burnout and occupational stress dimensions show that with the increase of occupational stress the dimension of emotional exhaustion also increases (r=0.493, p<0.01), that there is no significant correlation between occupational stress and the dimension of depersonalization, and that the dimension of occupational stress and the dimension of individual realization have significant connection (r=0.393, p=0.01). The results show that there is no statistically significant difference between departments when it comes to occupational burnout, i.e. nurses working in Surgery do not have higher results of occupational burnout than nurses working in Gynecology and Emergency F(0.679) p>0.05, and that there is no statistically significant difference between the departments in terms of occupational stress, i.e. nurses working in Surgery do not have higher occupational stress results than ones working in Gynecology and Emergency department F(0.722) p>0.05. The results do not show significant differences in the level of occupational burnout and occupational stress in relation to nurses' age and years of service. DISCUSSION AND CONCLUSION: The results of the study show that with increased occupationalstressoccupational burnout also increases and that nurses have low levels of occupationalstress, low depresonization, low level of lack of personal achievement and a medium level of emotional exhaustion. There were no significant differences in occupationalburnout and occupationalstress between nurses working in surgery, gynecology and emergency departments. No significant differences in occupationalburnout and occupationalstress were found in relation to the age and years of service of nurses working in the departments of surgery, gynecology and emergency.

A case of a patient is shown, who was admitted for neurological exploration, with clinical manifestations of the cerebrovascular accident in the posterior circulation (TIA V-B vascularisation). In accordance with diagnostic protocol, an endocranial CT was performed. The results of the brain CT indicated an existence of an alteration in the right pontocerebellar angle area, which was subsequently diagnosed as a n. vestibularis schwannoma in an NMR examination. After a neurosurgical deliberation, the patient was treated with a gamma knife. After this surgery, which was done in a local anesthesia, the patient's condition was well and he was discharged. Control examinations have shown minor difficulties during the stimulation of the left ear auditive structures. Control examinations involving NMR showed no signs of recidivate focal findings.

Introduction: Obesity is one of the seven leading risk factors for the occurrence of the most common non infectious diseases. An epidemic model of the obesity prevalence increase is also present in the student population. To identify an overweight person, who has an increased relative risk status and who did not develope clinically manifested cardiometabolic disorders is a critical moment for the effective obesity prevention and treatment program. Objective: To determine the prevalence and status of relative risk of developing overweight related diseases among students at the University of Pristina-Kosovska Mitrovica. AUTORI SAŽETAK ENGLISH ORIGINALNI RADOVI Uvod: Gojaznost je svrstana među sedam vodećih faktora rizika za nastanak najčešćih nezaraznih bolesti. Epidemijski model povećanja prevalencije gojaznosti prisutan je i kod studentske populacije. Prepoznavanje osobe sa prekomernom težinom koja je u statusu povećanog relativnog rizika a kod koje se još uvek nisu razvili klinički manifestni kardiometabolički poremećaji je poslednji trenutak za efikasan program prevencije i lečenja gojaznosti. Cilj rada: Odrediti prevalenciju i status relativnog rizika od razvoja bolesti povezanih sa prekomernom uhranjenosti među studentima Univerziteta u Prištini-Kosovska Mitrovica. Metode rada: Procena stepena relativnog rizika od razvoja bolesti povezanih sa prekomernom uhranjenosti rađena je na osnovu izmerenog indeksa telesne mase (BMI-Body mass index), obima struka (WC-Waist circumference) i kombinovano BMI sa WC. Rezultati: U ispitivanju je učestvovalo ukupno 1686 studenta (44,4% muškog pola i 55,6% ženskog pola). Srednje vrednosti telesne težine, BMI i WC bile su ispod vrednosti korišćenih tačaka preseka. Status povećanog relativnog rizika od pridruženih bolesti je imalo: prema BMI-20,2% studenata (27,8% muškaraca i 14,1% žena); prema WC-12,6% (12,2% muškaraca i 12,9% žena) i prema BMI sa WC-20,2% (27,8% muškaraca i 14,1% žena). Postoji značajna razlika u stopi prevalencije koji su u statusu visokog i veoma visokog nivoa rizika u zavisnosti od metode procene (samo prema BMI i prema BMI sa WC). Zaključak: Utvrđena je visoka stopa prevalencije predgojaznosti i gojaznosti, opšte i abdominalne među studentima Univerziteta u Prištini-Kosovska Mitrovica. Oni se mogu svrstati u grupu studenata sa statusom povećanog relativnog rizika od nastanka i razvoja bolesti povezanih sa prekomernom uhranjenosti. Savetovalište za ishranu i dijetetiku u okviru Studentskog centra prema njima mora intenzivirati mere prevencije i eventualnog lečenja gojaznosti.

Uvod: Primarni medijastinalni B krupnoćelijski limfom je redak, visoko agresivan oblik non Hodgkinovog limfoma i javlja se u 5-7 % svih difuznih velikoćelijskih B limfoma i 2% svih non Hodgkinovih limfoma. Vodi poreklo od medularnih ćelija timusa i ima sopstvenu histogenezu. Tipično obolevaju mlade žene u trećoj i četvrtoj dekadi života. Sindrom gornje šuplje vene je prisutan u više od 50% slučajeva, sa otokom lica, ruku, dubokim venskim trombozama, dispnejom, disfagijom, bolom u grudima, glavoboljom i kašljem. Dijagnoza se postavlja patohistološkom i imunohistohemjskom analizom hirurškog bioptata dobijenog medijastinoskopijom. Blagovremena terapija ciklusima monoklonskih antitela i polihemioterapijom omogućava stabilan relaps bolesti. Prikaz bolesnika: Pacijentkinja, stara 37 godina, javlja se prvi put na pregled kod svog izabranog lekara jer je već u nekoliko navrata posećivala Službu hitne medicinske pomoći zbog kašlja, osećaja da je nešto davi, nedostatka vazduha, pritiska i bolova u glavi kao i otečenosti vrata i lica. Započeta detaljna dijagnostika. Radiološki utvrđen tumor medijastinuma, kompjuterizovana tomografija potvrdila i poslata na referentni Institut gde je videoasistiranom torakoskopskom hirurgijom i patohistološkom analizom dijagnostikovan PMBCL CSII AM+. Ordinirano šest ciklusa rituksimab, ciklofosfamid, doksorubicin, vinkristin i prednizolon terapijskog protokola koje je podnela sa očekivanim neželjenim dejstvima. Kontrolna pozitronska emisiona tomografija utvrdila da se tumorska masa u potpunosti povukla. U remisiji je dve godine, dobro se oseća i javlja se na redovne kontrolne preglede. Zaključak: Na izabranom lekaru je velika odgovornost u prepoznavanju ranih simptoma maligne bolesti što ubrzava postavljanje konačne dijagnoze i blagovremeni početak lečenja.

Introduction: Thyroid nodules are defined as limited changes in the thyroid structure. A smaller number of thyroid nodules are palpable, only 10% in women and 2% in males. The prevalence of non-imperfect nodules visualized by ultrasound exploration of the structure of the neck (thyroid incidents) is 50%. Not malignant nodes can be found in people with thyroid hyperplasia, inflammatory and autoimmune thyroid diseases, granulomas, hemorrhagic or colloid cysts. Follicular carcinomas include follicular (papillary, follicular, anaplastic and insular carcinoma) and parafollicular carcinoma (medullary carcinoma). Case report:Apatient born in 1965 appears in a family medicine clinic for heart palpitations, malaise, and mood swings. Due to right-sided vetriculomegaly, diffuse reductive changes of the brain parenchyma, sensorimotor neuropathy of the right median nerve, sensory neuropathy of the right ulnaris and radial nerve, depression and arterial hypertension, it is under the supervision of a neurologist, physiatrist, psychiatrist and cardiologist. Physical examination reveals an enlarged, squamous thyroid gland, an ultrasonographically heterogeneous calcified malignantly suspected nodule in the lower poleleft lobe, 18x15 mm in size. The patient is referred to the Department of Nuclear Medicine where an FNAB is done indicating the presence of malignant cells. At the decision of the Oncology Consulium, a total thyroidectomy is performed at the Thoracic Surgery Clinic, followed by radioiodine therapy (131-I). The histopathological findings are: carcinoma papillare lobblateralis sinistri glandulae thyreoideae gradus II-classic type, T1N0. After 24 months, the patient without signs of relapse of malignancy. Conclusion: Educating family medicine physicians in the field of thyroid ultrasound diagnostics and incorporating it into everyday practice would allow significant advances in the diagnostic evaluation of thyroid nodules at the primary care level.