Primary angle-closure glaucoma (PACG) is highly prevalent in Asian countries, compared with primary open-angle glaucoma (POAG), which is reported predominant disease among Whites and that is the reason for paucity of reports about central corneal thickness (CCT) and corneal curvature (CC) in eyes with PACG in Europe. To determine central corneal thickness, corneal curvature and refractive error in patients with primary angle-closure glaucoma (PACG) and primary open-angle glaucoma (POAG). A total of 288 patients were enrolled into this study; 132 patients with PACG (mean age of 73 ± 7 years) compared with 156 patients with POAG (mean age of 70 ±7 years). The data was collected from all PACG patients who underwent Laser peripheral iridotomy at the Clinic for Eye Diseases, Clinical Center of Serbia in Belgrade between January 2012 and October 2012 and controls with POAG examined in the same period. Data from the right eye was used for analysis. In PACG/POAG mean CCT was 549±38/547±35 µm (p=0.353) and mean radius of corneal curvature (Cr) was 7.92±0.22/7.75±0.29 mm (p=0.003). There was no statistically significant correlation between IOP and mean Cr in PACG (p=0.244 ) and POAG ( p=0.637) while it was in POAG group with refractive error (p=0.005) and CCT (p<0.001). We found that CCT in PACG and POAG group were in normal range and there was no diference between them. Our results showed that the eyes with PACG had the flatter corneas than eyes with POAG and were hyperopic.
Quigley H, Congdon N, Friedman D. Glaucoma in China (and worldwide): changes in established thinking will decrease preventable blindness. Br J Ophthalmol. 2001;1271–2.
2.
Terminology and guidelines for glaucoma. 2014;100.
3.
Bonomi L, Marchini G, Marraffa M. Epidemiology of angle-closure glaucoma: prevalence, clinical types and association with peripheral anterior chamber depth in Egna-neumarkt glaucoma study. Ophthalmology. 2000;(5):998–1003.
4.
Nolan W, Foster P, Devereux J, Uranchimeg D, Johnson G, Baasanhu J. YAG laser iridotomy treatment for primary angle closure in in east Asian eyes. British Journal of Ophthalmology. 2000;(11):1255–9.
5.
Shih C, Graff Zivin J, Trokel S. Clinical significance of central corneal thickness in the managment of glaucoma. Arch Ophthlamol. 2004;1270–5.
6.
Miglior S, Pfeiffern, Torri V. Predictive factors for open-angle glaucomaamong patients with ocular hypertension in the European Glaucoma Prevention Study. Ophthalmology. 2007;3–9.
7.
Zhang D, Shi Y, Gong B. An association study of the COL1A1 gene ang high myopiain a Han Chinese population. Molecular Vision. 2011;3379–83.
8.
Doughty M, Zaman M. Human corneal thickness and its impact on intraocular pressure measure: a review and metaanalysis approach. Surv Ophthalmol. 2000;367–408.
9.
Pang C, Lee K, Su D, Htoon H, Ng J, Kumar R, et al. Central corneal thickness in Chinese Subjects with Primary Angle Closure Glaucoma. J Glaucoma. 2011;401–4.
10.
Mello P, Meirelles S. Moraes Junior HV. Correlation between central corneal thickness and axial length in patients with glaucoma and normal eyes. Arq Bras Oftalmol. 2009;497–502.
11.
Xu L, Zhang H, Wang Y, Jonas J. Central corneal thickness and glaucoma in adult Chinese: the Beijing Eye Study. J Glaucoma. 2008;(8):647–53.
12.
Shimmyo M, Ross A, Moy A. Intraocular pressure, Goldmann applanation tension, corneal thickness and corneal curvature in Caucasians, Asians, Hispanics and AfricanAmericans. Am J Ophthalmol. 2003;603–13.
13.
Nemesure B, Wu S, Hermis A. Corneal thickness and intraocular pressure in Barbados eye studies. Arch Ophthalmol. 2003;240–4.
14.
Aghaian E, Choe J, Lin S. Central corneal thickness of Caucasians, Chinese, Hispanics, Filipinos, African Americans, and Japanese in a Glaucoma Clinic. Ophthalmology. 2004;2211–9.
15.
Wolfs R, Klaver C, Fingerling J, Grobee D, Hoffmana, Jong P. Distribution of central corneal thickness and its association with intraocular pressure: Rotterdam Study. Am J Ophthalmol. 1997;767–72.
16.
Farm H, How A, Baskaran M, Lim K, Chan Y, Aung T. Central corneal thickness and its relationship to myopia in Chinese adults. Br J Ophthalmol. 2006;1451–3.
17.
Brandt J, Beiser J, Kass M, Mo G. Central corneal thickness in the Ocular Hypertension Treatment Study(OHTS). Ophthamology. 2001;1779–88.
18.
Paranhos A, Paranhos F, Prata J. Infuence of keratometric readings on comparative intraocular pressure measurements with Goldmann,Tono-Pen, and non-contact tonometers. J Glaucoma. 2000;219–23.
19.
Saleh T, Mcdermott A, Claridge B, Ewings K, P. Effects of central corneal thickness and corneal curvature on the intraocular pressure measurements by Goldmann applanation tonometer and ocular blood flow pneumatonometer. Clinical and Experimenatl Ophthalmology. 2006;516–20.
20.
Harada Y, Hirose N, Kubota T, Tawara A. The influence of central corneal thickness and corneal curvature radius on the intraocular pressure as measured by different tonometers: noncontact and goldmann applanation tonometers. J Glaucoma. 2008;(8):619–25.
21.
Orssengo G, Pye D. Determinationof the true intraocular pressure and moduls of elasticity of the human cornea in vivo. Bull math Biol. 1999;551–72.
22.
Lowe R. Aetiology of the anatomical basis for primary angleclosure glaucoma. Biometrical comparisons between normal eyes and eyes with primary angle-closure glaucoma. British Journal of Ophthalmology. 1970;(3):161–9.
23.
Xu L, Cao W, Wang Y, Chen C, Jonas J. Anterior chamber depth and chamber angle and their associations with ocular and general parameters. The Beijing Eye Study. American Journal of Ophthalmology. 2008;(5):929–36.
24.
Van Romunde S, Thepass G, Lemij H. Hyperopia an Important Risk Factor for PACG in the Dutch Population?-A Case Control Study. Journal of Ophthalmology. 2013;630481.
25.
Leske M, Wu S, Hennis A. Risk factors for incident open-angle glaucoma: the Barbados Eye Studies. Ophthalmology. 2008;(1):85–93.
26.
Perera S, Ty W, Tay W. Refractive error, axial dimensions and primary open-angle glaucomathe Sigapore Malay Eye study. Arch Ophthalmol. 2010;(7):900–5.
27.
Sihota R, Gupta V, Agarwal H. Comparsion of symptomatic and asymptomatic chronic PACG, open angle glaucoma and controls. J Glaucoma. 2000;208–13.
28.
Centralna Debljina Rožnjače ZRIRGKPSPGZIOU, Marić V.
29.
Klinika za očne bolesti, Klinički Centar Srbije.
30.
Srbija SAŽETAK Primarni glaukom zatvorenog ugla je znatno učestaliji u Azijiskim zemljama u odnosu na primarni glaukom otvorenog ugla koji je predominantan među Belom rasom te zbog toga postoji nedostatak podataka o centralnoj debljini i zakrivljenosti rožnjače kod primarnog glaukoma zatvorenog ugla u Evropi. Odrediti centralnu debljinu rožnjače, zakrivljenost rožnjače i refraktivnu grešku kod pacijenata sa primarnim glaukomom zatvorenog (PACG) i otvorenog ugla (POAG).
The statements, opinions and data contained in the journal are solely those of the individual authors and contributors and not of the publisher and the editor(s). We stay neutral with regard to jurisdictional claims in published maps and institutional affiliations.
