Besides big improvement of diagnostic, therapeutic and preventive procedures vascular disease generally and vascular disease of brain remain of biggest importance in total morbidity and mortality. This examination included patients in Urgent Surgery Center “Simonida” Gracanica. In article is represent relationship between brain and heart dysfunctions and it is obvious that cerebral disturbances can cause heart disturbances and also it can be in opposite direction. Well, based on this is very important to make fast and correct orientation: CARDIOCEREBRAL or CEREBROCARDIALSYNDROME. In diagnostic procedure and therapeutic treatment is necessary cooperation between cardiologist and neurologist because in most of these cases we have cardiocerebral or cerebrocardial syndrome. Better treatment patients with brain stroke claim teamwork different specialist.

Defined daily dose (DDD) is arbitrary chosen technical unit for measuring medicament usage and it is not a recommended therapeutic dose. It is in fact a statistical parameter for monitoring medicaments usage, and it is related to the dose which is usually prescribed for the indication that the medicament was registered for. The aim of this work is to perform a detailed analysis of the extent and structure of the region of South Backa. Antiinfective medicaments in systematic use, according to the obtained data, participate with only 7.96 DDD/1000 inhabitants. The most applied pharmacotherapeutic subgroup with 2.99 DDD/1000 inhabitants is comprised of cephalexine and cephachlor. 

Chronic pulmonary heart (CPH) stands for presence of hypertrophy and/or dilatation of right heart ventricle caused by pulmonary hypertension as a consequence of diseases that are damaging lungs function or structure. By chronic pulmonary heart are not considered those hypertrophies of right ventricle which are consequences of left cardiopaths or congenital heart anomalies with skips. During the CPH evolution three stages were formed: a) uncomplicated pneumopathology, b) compensated chronic pulmonary heart and c) decompensated chronic pulmonary heart. The disorders of cardiac rhythm are often at decompensated CPH, which is proved by this scientific work as well. 40 sick people diseased of decompensated CPH are treated in purpose to establish the presence and the characteristics of cardiac arrhythmia at these patients. It is established that the major percentage of frequency is made by sinus tachycardia, atrial extrasystols, and ventricular extrasystols. Of 40 examinees 65% had sinus tachycardia, 37,5% atrial extrasystols, 30% ventricular extrasystols and 20% combined atrial and ventricular extrasystols. This proves us that there is a significant percentage of cardiac rhythm disorder frequency at the sick people of decompensated chronic pulmonary heart.

Bacterial meningitis is an important medical problem, as because of the use of powerfull antibiotics and other
drugs, and therapeutic measures, the number of patients, as well as the mortality haven't been changed for years. Because of that the study of pathogenesis of bacterial meningitis has been one the most dynamic researsh fields in recent years. Meningitis caused by salmonella is not usual clinical manifestation of salmonella infections, but because of fulminant evolution and specific structure of cause. Path and effect of diseases, it deserves special attention. Our researches encompases 29 children who suffer from salmonella meningitis. Out of the whole number of cured children, the moust frequent was at newborn (58,6%), while the smallest number was in the group of older infant (6.9%). Concernig the sex structure of diseased, the biger number was at male (62.0%). The most important finding in liquor cerebrospinalis at patients is polymorphonuclear leucocytosis (average value of cell elements is 3744, with 82% polymorphonuclears). At the same time existed leucocytosis in peripheral blood with sigificant deviation into left. At all our patients hypoglycorachya expressed (1.45mmol/L). The value of proteinorachya was 1.71 g/L. The result of the disease was successful in 49.3%, died 24,1%, and cured with consequences 27,6%.

Today it is noticeable that the incidence and mortality from cervical carcionoma increases, especially the growth of
frequency of those changes at younger women. The total number of diagnosis of invasive carcinoma at the processed biopsy and operative matrials was 186. The majority of results were the histological grade G1 N1 54,83% in the group of 41-50 years old patients, and the less significant was number of histological grade G2 N2 at the age 51-60 and G3 N3 at patients over 60 years old. In 72 cases the radical surgical treatment was done after previously made HP diagnosis of planocellular carcinoma on the biopsy material, and it was done in the cases that were operable in stage Ib (FIGO). The most of operated women were with histological grade G1 N1, so we followed in what degree the size of tumor, beside the histological grade G1 N1, so we followed in what degree the size of tumor, beside the histological grade, have an effect on the possibility of presence of the metastasis in regional lymphatic nodes. We came to the conclusion that with the growth of macroscopically size of tumor, the frequency of appearance of lymphatic nodes increases. Those parameters could not the small number of operated cases. When the disease is discovered in these histological grades. It is not operable, and then we perform radiotherapy as a method of treatment.

On autopsy material of fifty corpses, age 0-75 (Institute for Pathology of Medicine Faculty in Belgrade and KBC
Dragiša Mišović - Dedinje, Beograd) we have met with all kind of comlications of bronchyectazia and bronchyloectazia
which were mentioned in literature. All statement complications, which caused death, we classified into lung and out lung
ones. Among lung complications, we stated that pneumonia among children in a big number of cases of congenital
bronchyectazia and cystic fibrosis of lungs. The apses of lungs were represented in four cases of secular and spindle shaped bronchyectazia and in one case of distal secular bronchyectazia it was represented in empiem pleure. In two cases lung gangrene was noted. Among out lung complications we can emphasize two cases of sepses of brain Apses. Leptomeningitis was present at one case. Among long-term spread bronchyectazia and bronhyloectasis with chronically manure inflammation and lung abscesses (bronchiectasiae abscendons), we stated the deposit of amiloids in glomerulus's and blood vessel of kidney intersticium as well as in liver and spleen. Chronical lung heart (cor pulmonale chronicum) was the most often complication of bronchyectazia and bronchyloectasia in the middle and older age period of our cases and it had represented the major cause of death.

Foreign bodies of the lower respiratory ways represent a very important chapter in ENT and medicine in general,
becouse they can lead to child fatal results in very short time due the obstruction and suffocation. They considered as some of the most urgent states in medicine, so that the childs life depends on correctly and quickly made diagnostic and skilfully do
ne intervention. The authors have analysed the importance of anamnesis at the patients which have the foreign body in the
lower respiratory ways, hospitalized at the ENT Clinic and Pediatric Clinic of the CHC Priština, during the period of 1994 -
1999. Results of ork are showed that 132 childrens have been hospitalized during this period, and 119 of them were with
positively anamnesis for foreign body, while 13 were with negatively anamnesis, but with positive clinical and/or radiolo
gical findings. From 119 patients with positively anamnesis, 82.38% had positive TBSC finding, while patients with nega
tively anamnesis (13) had positive TBSC finding in 23.08% cases. The largest number of the children has been male pole
(64.36%), of the age of 3 and younger (73.27%), the most frequent foreign body was raw grain of bean (31.69%), and peanut (16.83%), and the most frequent localisation has been the right bronchi (57.43%). The most foreign bodies have been extracted by the upper tracheobronchoscopy (99.01%), while in only 0.99% of the cases tracheostomy and lower tracheobron choscopy applied. Positive anamnesis for foreign body of the lower respiratory ways was sufficient reason to indicate a tracheobronchoscopy, but if patients had positively clinical and/or radiological findings, negatively anamnesis must be interpreting very carefully

In February 2000, in Pancevo, 71 persons suffered from trichinosis. Of that number, 47 were hospitalized. In one of
the cases, which is a subject of this work, patient developed clinical feature of encephalitis. Encephalitis was diagnosed
based on clinical feature, EEG and spine fluid results. In the another case, that this work also deals with, toxic myocarditis
was developed. This diagnosis is based on clinical feature, changes in ECG and ultrasound of heart. Changes in ultrasound
of heart were noted 33 days after first symptoms had occurred.

The genes mutate either spontaneously or under the influence of mutagenic agents (irradiation, viruses, toxins).
The occurrence of genetic syndromes in the scope of one family is pointing more to the inherited than to de novo mutation.
Aim of this study was to present two syndromes in the same family tree, occurring subsequently one by one, which carry severe mental retardation and have a poor prognosis and frequently tragic outcome. A case report was given of a patient in
whom both pregnancies were completed by birth of the newborns presenting with severe syndromes: the first one with
Down's syndrome and the second one with Prader-Willi-Labhart syndrome. The results of investigation point to the necessity of genetic investigations before pregnancy and during pregnancy as early as possible, in order to avoid giving birth to
the children with syndromes which bear severe mental retardation and having poor prognosis.

Condylomata gigantea is an expansive, destructive lesion that affects most frequently anal and perianal region, and
rarely vulvar and vaginal region. We will describe a clinical case of a 28 years old female patient with a diagnosis of Condylomata gigantea in anal and perianal region with propagation on vulva, vagina and clitoris. After we detected a wide base of condylomas in anal and perianal region, we performed a deep, multiple biopsy for discover of eventual malignancy.
Histologically, malignancy was not confirmed, but it was discovered a presence of HPV types 6 and 11. The patient was initially treated with a wide surgical excision, and then the rest of condylomas were removed using CO laser which had an 2
haemostatic function in the same time. Three months later, there was no recurrence.