The complement system (complement) involves over 30 circulating and membrane-fixed proteins with an effector
role in the innate and humoral immunity. These proteins help the function of antibodies to protect the organism from foreign
molecules (antigens) which the term complement comes from. Soluble proteins of the complement system made mainly in
the liver and circulate in blood in an inactive form. The activation of complement may be initiated in three ways (classical,
alternative and lecitin pathway), and it is realized by sequential proteolysis of complement proteins (proenzymes) which
become emzymes with the proteolitic activity after cleavage. Products of the activatin of complement bind to the surface of
microbes or to the antibodies bound to antigens. An activated complement shows a number of biological effects, such as
lysis of an attached cell, opsonization, neutralization of viruses, inflammation, clearance of immune complexes etc. In contrast of microorganisms, human cells have a number of regulatory proteins which prevent the complement activation and in that way, they regulate its activity

Identification of the deceased is routine and, for experts, quite a simple forensic procedure. However, in the case of
mass accidents such as explosions, traffic accidents, natural disasters, and during the war everything is much more different.
There are a lot of differences between forensic medicine in the peace and the forensic medicine during the war. The cause of
this claim comes from special conditions for performing the forensic procedures during the war, with much more activities,
a lot of differences and special characteristics of war injuries. We have in mind mass war injuries and great number of victims, which can grow till catastrophic proportions. That includes killing a great number of people in different places, in
different military units and civilian settlements. The identification of these victims is, certainly, the most important and permanent task of forensic medicine which consider, first of all, collecting, identification and transportation of the victims. The
complexity of these tasks is severe when mass deaths occur, but also when killings happened in the different locations in the
same time, also, during the discovering of the victims which become putrefied and decay, where the biggest problem is to
identify the victim and determine the cause of death.

All formsspondyloarthropaties are uniteded with HLA-B27 antigen's in 70-100% in dependences of form illneses and so ethenic and eugenic qualifications. Consider that some Gram-negative bacteriums can have place in pathogenesis of spondyloarthropaties. Explored are 24 patients(15 men and 9 women) with seronegative spondyloarthropaties. Absence of
bacteriums which besides other factors inculpate for pathogenesis seronegative spondyloarthropaties in explored materials,
points to need for proving their antigens at synovium woof or anti-bodies in serum toward specific antigens.

Perinatal infection occurs as a consequence of the intrauterine (congenital) infection, intrapartal infection, or the
newborn infection in the course of its nursing. Congenital cytomegalovirus infection is a most frequent intrauterine infection. The prevalence of congenital CMV infection given by different authors varies significantly, but the majority of them
mention that it is in the range from 0.5 to 2.5 % of the number of the live-born. Significance of this disorder is underlined by
the fact that about 20% of intrauterine infected newborns have later serious problems in their development. The signs of fetal
impairments with congenital CMV infection can be noticed with about 10 % of the infected newborns at the very birth. The
mortality rate among these newborns is high even about 30 % of them exhibit heavy signs of the disease and die very soon
after the birth. Even with 70 % of the newborns with the symptoms of congenital CMV infection it is possible to notice at the
birth the presence of the symptomatology related to CNS, and this is of predicative significance for the later unfavorable
development of the infant. It should be pointed out that, in contrast to intrauterine infection, which provenly yields to fetal
impairments, there are no reliable data that would point to undesired outcomes of intra- or postpartal infections. The work
gives a survey of contemporary knowledge about cytomegalovirus infection in perinatology, as well as about the possibilities of its diagnosis and treatment.

Anorectal abscesses and fistulas are problems that are commonly encountered together. Occasionally, their management can prove to be formidable, constantly challenging the clinical and surgical skills of the practicing surgeon. This article reviews the etiology, presentation, and treatment of anorectal abscesses and fistulas.

Urea is naturally present in healthy skin,but when the skin is dry, and in some skin condicions, such as eczema, psoriasis and dermatitis, the level of urea in the skin is reduced, because skin is dry and rough and irritation. Urea deserves a bigger role in our dermatotherapy and medical cosmetology-for curring skin disorders and for better care of healthy skin. Urea
helps replenish this essential skin component and help support the skin`s natural moisture levels.

Chronic appendicitis presents inflammation of appendix with atypical clinical findings, without significant signs
and symptoms. Because of that diagnosing chronic appendicitis presumes a great problem. Indications for operative treatment based on clinical impression are followed with a great number of unnecessary appendectomies. Barium enema can show morphlogic changes of appendix during its chronic inflammation. Our aim was to show values of barium enema in diagnosing chronic appendicitis. Study went prospectively, in period 1999-2001 on Clinic for abdominal and endocrine
surgery, Institute for surgery Novi Sad. It includes 100 patients with symptoms, 50 of them were operated after barium
enema, and other 50 were operated after clinical impression of surgeon. Each appendix was patohistologicaly examined.
Incidental appendectoies were exluded. Of total 1425 appendectomies in three years period, 100 were operatde because of chronic appendicitis. Fifty of them were operated after barium enema, and other 50 were operated after clinical impression of surgeon. Range of years was 15 59 in examined group with average 35,6 years. In control group range was 15 57, with average 32,9 years. Lasting of pain episode more than 12 hours had 94% of patients in examined group, and 72% of patients in control group had painn less than 24 hourrs. During of pain episodes at 92% of patients from examined group was 3 weeks to 12 months, and 86% of patients from control group had pain standing 3-36 weeks. The most common sign on barium enema was finding of coprolites in lumen (52%), followed with unfilled appendix (18%, angulations (10%), distal amputation (8%), segmentation of contrast (8%), and fixated appendix (4%). Intraoperative macroscopic findings were as followed: 40/50 coprolites in lumen, 7/50 fibrous bounds, and 3/50 fibroses of appendix. Patohistologicaly, chronic appendicitis was confirmed at 90% of patients in examined group, and 58% in control group. After surgery, 94% of patients from examined group don't feel the preoperative pain. Barium enema significantly increases of chronic appendicitis. It is non-invasive, and reliable method for showing morphologic changes of chronic appendix. Use of barium enema dereases number of unnecessary appendectomies. Barium enema is suggested for evaluation of patients with chronic pain in right lower quadrant of abdomen, and thereby for diagnosing of chronic appendicitis. 

The patients after the stroke besides impaired motor functions,often have cognitive and emotional disorders which
can endanger the successful carrying out of the rehabilitation treatment. The objective of this study was to estimate the
functional capability and to determine the cognitive and emotional disorders of the patients after the stroke. The research has
ecompassed 40 patients after the stroke of specified age and gender structure, treated in the Clinic for Rehabilitation, of the
Clinical Center in Novi Sad. The data have benn gathered from the anamnesis, clinical and neurological check, test of the
activity in everyday life, the findings of the psychologist on the emotinal status, as well as from the available medical
documentation about the patient. The average values of the Barthel's index are increased for 14.86% after the rehabilitation
treatment. The results show a strong presence of the emotional disorders with 57.5% of the patients. The increased values of Barthel's index and Mini Mental test at the end of the treatment show the undoubtfull importance of the rehabilitation
treatment in the recovery of the patients. The emotional disorders cause the worse recovery of the patients.

Sindrom X or Metabolic Syndrome are both terms used to describe a collection of herth risks contitions that increase your chance os developing heart disease, stroke and diabetes. The condition is aslo known by other names including insulin Resistence syndrome, and Dysmetabolic syndrome. The number of people with Metabolic Syndrome increases with
age, affecting more than 40 percent of people in their 60 s and 70 s. Components of Metabolic Syndrome are: Abdominal obesity, atherogenic dyslipidemia, raised blood pressure, insulin resistance, proinflamate state and prothrombotic state. The
National Cholesterol Education Program 's Adult Treatment Panel III report (ATPIII) identified 6 components of the metabolic syndrome that relevate to CVD. Insulin resistance is present in the majority of people with the matabolic syndrome.
It strongly associates is present with other metabolic risk factors and correlates unuvariately with CVD risk. Patiens with
longstanding insulin resistance frequently manifest glucose intolerance. When glucose intolerance evolves into diabetslevel hyperglicemia, independent risk factor for CVD. When 3 of 5 of the listed caracteristics are present, a diagnosis of metabolic syndrome can be made. The exact cause of Metabolic syndrome is not known. Most reserchers believe it is caused by
a combination of your genetic makeup and lifestyle choices-including the types of food you eat and level of physical activity.

The main goal of this research was to present the mikid generalised reaction in children who suffered from trichophytiae profundae capillitii. After the infection and the inflammation brought on by the direct contact with the sick calves, the intensive mikid reactions occured, that is, the aseptic lesions of the skin. From 149 sick children, hospitalised at the DVC in Priština, 63(42,28%) were with the diagnosis of Kerion celsi. In 7(11,11%) cases trichophytid reactions occured to the animal type of the trichophyton mentagrophytes. The inflammed regions of the kerion produced the secondary bacterial infection with the regionale lymphadenopathy. Two weeks later antibodies and skin rash were produced in response to the infection agents. Early diagnostice and the adequate therapy decreases frequency of the mikid reaction in childrens age