Premature labour is provoked by noumerous causes that represent a combination of socioeconomic, maternal and fetal factors, that usually act together. The introduction of of tocolytic agents in obstetric practice has not appeared to substantially change the incidence of preterm delivery. This problem is still one of the unsolved ones in perinatal medicine. The aim of the study was to present how structural and functional anomalies of placental physiology can be connected with this disarrangement of pregnancy.In our study of 327 pregnancies controled in our unit in 41 (13,26%) symtoms of premature labour were present: contractions, vaginal bleeding, abrevation and dilatation of cervical ostium. With adequate treatment, in form of combination of tocolytics, spasmolytics, hormones, nonsteroid antiinflammatorz drugs, antibiotics and atimycotics we have posponed delivery to term in 34 (82,92%) of cases. The use of appropriate medications, that blocks pahtophysiological mechanisms responsible for preterm labour in most cases we can enable prolongation of gestation and term delivery.

In regulation of specific immune responses the most important role play interleukin-2, IL-4, IL-5, IL-13, inter feron- (INF- ), transforming growth factor- (TGF- ) and lymphotoxin (LT). These signal molecules are produced mainly by T-lymphocytes after recognition of foreign antigens by specific receptors (TCR) placed on plasmalema. Some of mentioned cytokines stimulate proliferation and differentiation of various lymphocyte populations in the activation phase of T cell-de pendent immune responses, while the others activate and regulate the function of specialized effector cells, such as mono nuclear phagocytes, eosinophils, and neutrophils, to eliminate antigens in the effector phase of immune responses. In con trast to most of cytokines which have stimulating action on an initiation and course of humoral and cell-mediated immune responses, TGF- has an inhibitory effect on the activation and proliferation of T-lymphocytes and the other leukocyts

Osteoporosis is a condition chracterized by a reduced amount of bone which leads to diminihed physical strength of the skeleton and an increased susceptibility to fractures. There are many causes of osteoporosis but the most common by fair is due to the decrese in the amount of bone which occurs after the menopause, the so called postmenopausal osteoporosis. There is no evidence that postmenopausal bone loss itself causes any symptoms and ensuing osteoporosis has therefore been called «the silent epidemic».

Women sexuality is a complex phenomenon encompassing biological, psychological, emotional and social aspects. The menopausal changes have undoubtedly a significant influence on sexuality. There is a widespread opinion that older women show a fading interest and desire for sexual relations. However, despite of all unavoidable changes brought about by menopause and elder age, the sphere of sexuality remains still very important. The paper reviews the changes occurring in the sphere of sexuality in the older age, influence of menopausal hormaonal changes, psycho-social factors and general health state in these changes, as well as of the possibilities of treating sexual dysfunctions in the menopausal period.

Foreign bodies of the lower respiratory ways represent a very important chapter in ENT and medicine in general,
becouse they can lead to child fatal results in very short time due the obstruction and suffocation. They considered as some of the most urgent states in medicine, so that the childs life depends on correctly and quickly made diagnostic and skilfully do
ne intervention. The authors have analysed the importance of anamnesis at the patients which have the foreign body in the
lower respiratory ways, hospitalized at the ENT Clinic and Pediatric Clinic of the CHC Priština, during the period of 1994 -
1999. Results of ork are showed that 132 childrens have been hospitalized during this period, and 119 of them were with
positively anamnesis for foreign body, while 13 were with negatively anamnesis, but with positive clinical and/or radiolo
gical findings. From 119 patients with positively anamnesis, 82.38% had positive TBSC finding, while patients with nega
tively anamnesis (13) had positive TBSC finding in 23.08% cases. The largest number of the children has been male pole
(64.36%), of the age of 3 and younger (73.27%), the most frequent foreign body was raw grain of bean (31.69%), and peanut (16.83%), and the most frequent localisation has been the right bronchi (57.43%). The most foreign bodies have been extracted by the upper tracheobronchoscopy (99.01%), while in only 0.99% of the cases tracheostomy and lower tracheobron choscopy applied. Positive anamnesis for foreign body of the lower respiratory ways was sufficient reason to indicate a tracheobronchoscopy, but if patients had positively clinical and/or radiological findings, negatively anamnesis must be interpreting very carefully

Urea is naturally present in healthy skin,but when the skin is dry, and in some skin condicions, such as eczema, psoriasis and dermatitis, the level of urea in the skin is reduced, because skin is dry and rough and irritation. Urea deserves a bigger role in our dermatotherapy and medical cosmetology-for curring skin disorders and for better care of healthy skin. Urea
helps replenish this essential skin component and help support the skin`s natural moisture levels.

The main goal of this research was to present the mikid generalised reaction in children who suffered from trichophytiae profundae capillitii. After the infection and the inflammation brought on by the direct contact with the sick calves, the intensive mikid reactions occured, that is, the aseptic lesions of the skin. From 149 sick children, hospitalised at the DVC in Priština, 63(42,28%) were with the diagnosis of Kerion celsi. In 7(11,11%) cases trichophytid reactions occured to the animal type of the trichophyton mentagrophytes. The inflammed regions of the kerion produced the secondary bacterial infection with the regionale lymphadenopathy. Two weeks later antibodies and skin rash were produced in response to the infection agents. Early diagnostice and the adequate therapy decreases frequency of the mikid reaction in childrens age

Sindrom X or Metabolic Syndrome are both terms used to describe a collection of herth risks contitions that increase your chance os developing heart disease, stroke and diabetes. The condition is aslo known by other names including insulin Resistence syndrome, and Dysmetabolic syndrome. The number of people with Metabolic Syndrome increases with
age, affecting more than 40 percent of people in their 60 s and 70 s. Components of Metabolic Syndrome are: Abdominal obesity, atherogenic dyslipidemia, raised blood pressure, insulin resistance, proinflamate state and prothrombotic state. The
National Cholesterol Education Program 's Adult Treatment Panel III report (ATPIII) identified 6 components of the metabolic syndrome that relevate to CVD. Insulin resistance is present in the majority of people with the matabolic syndrome.
It strongly associates is present with other metabolic risk factors and correlates unuvariately with CVD risk. Patiens with
longstanding insulin resistance frequently manifest glucose intolerance. When glucose intolerance evolves into diabetslevel hyperglicemia, independent risk factor for CVD. When 3 of 5 of the listed caracteristics are present, a diagnosis of metabolic syndrome can be made. The exact cause of Metabolic syndrome is not known. Most reserchers believe it is caused by
a combination of your genetic makeup and lifestyle choices-including the types of food you eat and level of physical activity.

Trabeculodisgenesis of the primary congenital glaucoma because of the iris affiliate in front of the scleral ridge in
angulus iridocornealis. It is treated both surgically and with medication. We have showed you a patient which has, by the
time of illness diagnosing, developed morphological and functional optic papilla damages. We have applied both
comparative examinations and x-rays before and after sol. Xalatan therapy. With the research which is stillin progress, it is
estabilished that the values of intraocular pressure are brought to statistically normal frame (1,3 kPa-2,9kPa) and the
progression of both eyes´ optic nerves ganglion cells decadance is reduced, too

Acute louse born typhus is a nightmare to which our scientific medicine have provided significant importance.
Doctors in former Yugoslavia deem that the louse born typhus was rooted in Bosnia and Herzegovina from long time ago,
while in Serbia were individual cases without areas with pediculosis before the First World War, and there were no cases of
body pediculosis in villages. The author conducts medical, but also historical and linguistical research in order of collecting
data on louse borne typhus cases through information on causes of death written in death certificates. The research was done in more phases. The citizens were tested through questionnaires at the area of lower prevalence of louse borne typhus (only sero-positive cases); then at the area of higher prevalence (population through random sample). Contact with R. Prowazeki was established through sensitive serological method. In the final step, the popular name for typhus syndrome was checked - that is, if that name has been written into the death certificate. The objective of the research is to check if there were cases of louse borne typhus in the area of Metohia, and that was done through checking the death certificates. The author proves the endemics of the disease through explicit and implicit use of the name for the louse borne typhus during 1914 to 1935. This empirical check is the basis for the future researches of earlier endemic of louse borne typhus, this time through checking older documents from the used death certificates, which is kept in the archive of Serbia, town of Kotor, and other places.