In this work we present a basic aspects of ionising radiation (afterward of depleted uranium), this effects to human organism, esspecially on radiobiological, health effects on human skin. Health effects ionising radiation on skin depends of its doses. High doses given stron reaction, already in a few days after radiation, and later manifestations arise after longer exposition lower doses this radiation. In this work we present a basics pathophysiological aspects, without specifical clinical manifestations of radiation dermatitis.

Sjögren'ssyndrom is autoimmune disorder where cells of immune system afack and destroy eccrine glands which produce tears and spit. We have a patients with following problems: dryness of the bucal lining and conjunctiva, dysphagia of solid food, paint in joints amd muscles, hand sensitivity to coldness.

Traumatic extraction of permanent teeth (avulsion completa) is a serious teeth injury with uncertain outcome and it requires dentist's on duty fast and adequate reaction. In this study a complete therapy plan for eleven year old girl, who came to the Clinic because of avulsed teeth 11, third class fracture of tooth 12 and second class fracture of tooth 21, was showed. After clinical examination and upper frontal region X-ray, we started with replantation of the tooth 11, as well as with wirecomposite splint placement. After successfully done replantation and injured teeth endodontic treatment, prosthetic sanation of the patient was done. In this study, clinical picture of the patient one year after the injury was also showed.

Eosinophilic Granuloma (EG) represent the most benign and localized form of the three Langerhans cell histiocytosis syndromes. In bone, it is a tumor-like proliferation Langerhans cells. Intraosseous EG lesions can be solitary or multifocal. EG accounts for 60-70 % of Langerhans cells histiocytosis cases. The authors are describle a 21 year-old men with Eosinophilic granuloma. The disease had a rarely course with disorders multiple lesions in bones

Nonsteroidal antiinflamatory drugs are currently one of the most widely used categories of drugs, because there is a huge number of indication for theirs purpose. This huge purpose of this drugs has theirs own price, which is shown in side effects, especialy in the upper parts of gastrointestinal tract: erosions of the mucose in 35-60 %, ulcers in 10-25%, strong bleeding or perforation in <1%. It is appears that this drugs are responsible for 10-20 thousands lethal outcome in the world. Even small dose of acetlisalicil acid by 75 mg,which is used in prevention of cardiovascular disease, brings to the damage of mucose GIT and 11% have ulcer. Inhibition ciklooxigen-1,which have main role in protection mucose of stomach and duodenum on the part of NAIL, lead to damage mucose GIT, and that is the result of sistemic inhibition, which is indenpendant of the way of getting drugs. Some author instigate a local effect of Nail,as week acid. It is necessary to protect highrisk pacient with using gastroprotektiv drugs

Allergen-specific immunotherapy (SIT) is the practice of administering gradually increasing quantities of an allergen extractto an allergic subject to ameliorate the symptoms associated with the subsequent exposure to the causative allergen. The major objectives of SIT in alergy disorders are, in the short term, to reduce the allergic triggers precipitating symptoms, and, in the long term, to decrease allergy inflammation and nonspecific bronchial hyperreactivity when bronchial remodeling is not prominent. The mechanisms of SIT are complex but it was convincingly shown to act by modifying Th2 cell responses either by immune deviation (increase in Th0/Th1) or T cell anergy (decrease inTh2/Th0) or more likely both. Specific immunotherapy is the only treatment that may alterthe natural course of allergic disease.

Periodontal disease is a chronic inflammatory disease that is largely attributable to infections with gram-negative bacteria and is characterised by both gingival inflammation and alveolar bone resorption. Beside macrophages, the second most common cells of the gingival inflammatory infiltrat are mast cells. Mast cells are heterogenous cell population which live from six months to one year. These cells are activated by differnt immunologic and non-immunologic signals. Activated mast cells can secrete a range of substances that regulate angiogenesis, tissue remodeling and wound healing, which include both degradation and synthesis of tissue components. Apart from that, mast cells have an important role in phagocytosis, antigen processing and presentation to T-cells. It is confirmed that gingival mast cells can express matrix metalloproteinases (MMPs) and the tissue inhibitors of metalloproteinases, TIMP-1 and TIMP-2. This indicates that mast cells are likely to play an important role in inflammation and tissue degradation in periodontal diseases.

Work construe problems in children's protenuria.It is about physiology, pathological and insulated protenuria, also observation of examination stages of children with protenuria. It is about glomerul filtration and ultrafiltration barrier. Histochemical aspect show us that membrane is between palmately extensions and electromicroscopically aspect which indicate on subendotel part of basic membrane. About tubular absorption and removing of albumin from primary ultrafiltrate. Work is about proximal tubul and mechanism for reabsorption and transport of protein and peptid. Pathological protenuria is segmented on glomerul,tubul,hiper-production/overflow,and histuria. Work contains protenuria in different forms, transitiv, ortostatic and persistence. There are prepositions of three phases in examinations of protenuria

There are many forms of physical energy which, during such a short period of time, had rich history and which found wide application in the science of medicine, as was the case with the ultrasound in the last fifty years or so. The ultrasound got its affirmation rather soon, as valuable biologically harmless method used for detecting and explaining various pathological conditions in the science of medicine, and therefore in otorhinolaryngology as well. In the following study, the technique of the ultrasound examination of paranasal sinuses is described in details, standard echogramic patterns are
represented, and means of their interpretation are explained as well, regarding the fact that it is not standard. Special focus is
on the literature review whereby the valorization of the ultrasonography in relation to acute and chronic diseases of the maxillary sinuses is performed. In that sense, over 30 extracts by the authors from all parts of the world are represented. The
insight into the results of the latter reports, as well as the author own experiences, lead to the conclusion that the A-mode
ultrasonography represents an impartial method applicable in diagnostics of the maxillary sinus diseases. It is practical and
economical for it is performed quickly and in a rather simple manner. It is an invasive and painless method, comfortable for
the patient. Main advantage in relation to other radiological methods lies in the avoidance of the patient and medical doctor's
exposure to X-rays, therefore the ultrasonography method is a matter of choice for diagnosis of primarily maxillary sinus
acute diseases with children and pregnant women. Due to extraordinary sensitivity in the evaluation of the sinus secret, with
acute diseases it represents valuable, impartial supplementary method. On the other hand, due to weaker peculiarity, with
chronic diseases ultrasonography only represents a selective method

Despite progress in conventional pharmacology in producing effective drugs, the plant kingdom might provide a useful source of new anti-ulcer compounds for development pharmaceutical entities or, alternatively, as simple dietary adjuncts to existing therapies. Botanical compounds with anti-ulcer activity include flavonoids(i.e.quercetin, naringin, silymarin, anthocyanosides, sophoradin derivatives) saponins (i.e. from Panax japonicus and Kochia scoparia), tannins (i.e. from Linderae umbellatae), gums and mucilages (i.e. gum guar and myrrh). This article reviews the gastro-protective and anti-ulcer properties of the most commonly employed herbal medicines and their identified active constituents. Among herbal drugs, liquorice, aloe gel and capsicum (chilli) have been used extensively and their clinical efficacy documented, but тhe documented literature has centred primarily on pharmacological action in experimental animals.